Low COVID-19 vaccine hesitancy in Brazil.

BACKGROUND: The COVID-19 pandemic has affected the entire world, and the vaccine has emerged as a source of hope for return to normal life. Still, various countries have reported high vaccine hesitancy rates. It is important to know the vaccine hesitancy profile in Brazil to help design adequate communication strategies. METHODS: A voluntary, anonymous online survey was conducted from January 22 to 29, 2021, including resident Brazilian adults to assess factors related to vaccine hesitancy. Sociodemographic and epidemiological data were analyzed. A bivariate analysis was conducted with the independent variables, with vaccine hesitancy as the outcome variable, and a multivariate logistic model was used to calculated adjusted odds ratios. RESULTS: The sample included 173,178 respondents, and vaccine hesitancy was found in 10.5%. The principal factors associated with vaccine hesitancy were the following: assigning importance to the vaccinés efficacy (AOR = 16.39), fear of adverse reactions (AOR = 11.23), and assigning importance to the vaccinés country of origin (AOR = 3.72). Other risk factors were the following: male gender (AOR = 1.62), having children (AOR = 1.29), 9 years of schooling or less (AOR = 1.31), living in the Central-West region (AOR = 1.19), age ≥ 40 years (AOR = 1.17), and monthly income < U$788.68 (AOR = 1.13). The two vaccines available in Brazil, Covishield and CoronaVac, showed similar confidence, 80.13% and 76.36%, respectively, despite the higher rejection of the latter vaccinés Chinese origin. INTERPRETATION: This online survey confirms the low vaccine hesitancy rate among Brazilians and allowed the identification of a profile that can assist the elaboration of communication strategies to increase vaccine adherence. FUNDING: National Institute of Women, Children and Adolescents Health Fernandes Figueira, FIOCRUZ, Rio de Janeiro, Brazil.

Prognostic factors of death in children during the first year of life due to congenital diaphragmatic hernia: analysis of a hospital cohort from 2005 to 2015.

OBJECTIVE: To describe and analyze the prognosis of children during the first year of life with a diagnosis of congenital diaphragmatic hernia admitted between the years 2005 and 2015 in the Neonatal Intensive Care Unit. METHOD: In a retrospective cohort, 129 children with a diagnosis of congenital diaphragmatic hernia were studied. The prognostic factors were analyzed, whereupon prenatal, delivery, and postnatal exposure variables were associated with death during the first year of life. The odds ratio and the confidence interval (95% CI) were calculated for all the studied variables, using the chi-squared test and Student's t-test. RESULTS: The study included 129 children hospitalized from January of 2005 to December of 2015. Seventy-nine (61%) patients died, 50 survived, and 33 had other associated malformations. Among the prognostic factors, the following were significant and increased the chance of death: polyhydramnios (p=0.001), gestational age of the earliest diagnosis (p=0.004), associated congenital abnormalities (OR: 3.013, p=0.022), pO2 of the first gasometry (p=0.000), pCO2 of the first gasometry (p=0.000), presence of pulmonary hypoplasia (OR: 3.074, p=0.000), use of preoperative vasoactive drugs (OR: 2.881, p=0.000), and use of nitric oxide (OR: 1.739, p=0.000). The presence of only intestines in the hernia content was a protective factor (OR: 0.615, p=0.001). CONCLUSION: The mortality in the first year of life in patients with congenital diaphragmatic hernia in this study was 61% in the years 2005-2015. Among the prognostic factors that demonstrated a significant effect, pulmonary hypoplasia had the greatest impact.

Aconselhamento sobre o teste rapido anti-HIV em parturientes / HIV rapid test counseling among parturient

Introdução: O aconselhamento pré e pós-teste anti-HIV é preconizado pelo Ministério da Saúde, e constitui-se em ferramenta para a reflexão e tomada de decisão conjunta. Objetivos: Verificar a proporção de parturientes que receberam aconselhamento por ocasião da submissão ao teste rápido anti-HIV e analisar os fatores associados ao não recebimento de aconselhamento por estas parturientes. Método: Estudo transversal conduzido nos cinco “Hospitais Amigos da Criança” do Sistema de Gestação de Alto Risco do município do Rio de Janeiro. A população do estudo foram 955 mães submetidas ao teste rápido anti-HIV internadas em alojamento conjunto entre 11 de setembro e 11 de dezembro de 2006. Foram aplicados questionários às mães e coletados dados do laboratório e do prontuário materno. Para análise das variáveis associadas ao não recebimento de aconselhamento utilizou-se a regressão multivariada binomial. Resultados: Foram submetidas ao teste rápido anti-HIV 28,5% das parturientes. Destas, apenas 26,9% foram aconselhadas. Os fatores associados ao não aconselhamento foram: escolaridade materna inferior a 8 anos de estudo (RP = 1,36; IC 95%: 1,15-1,62), realização de 0 a 3 consultas de pré-natal (RP = 0,73; IC 95%: 0,59-0,90) e parto em hospitais com menos de 50% das parturientes submetidas ao teste-rápido anti-HIV (RP = 1,65; IC 95%: 1,40-1,96). Conclusões: As mulheres em situação socialmente desfavorável não foram alvo de aconselhamento, e apenas o baixo número de consultas pré-natais mostrou-se um fator de proteção contra o não aconselhamento. O aconselhamento foi pouco praticado por ocasião da r...

Introduction: The pre and post-HIV test counseling is recommended by the Ministry of Health, and is a tool for reflection and joint decision-making. Objectives: To determine the proportion of women receiving counseling for submission to the HIV rapid test and to assess factors associated to not receiving counseling for this test. Method: A cross-sectional study was conducted in five “Baby-Friendly Hospitals” from the High Risk Pregnancy System in Rio de Janeiro City, Southeast Brazil. The study population were 955 rooming-in parturients, undergoing the HIV rapid test, between September 11thand December 11th, 2006. Semi-standardized questionnaires were applied to the mothers, and data were also obtained from laboratory and health archives. Binomial regression was performed in order to analyze the variables associated with non-counseling. Results: Were submitted to the HIV rapid test 28.5% of the parturients, and only 26.9% of them were counseled. Factors associated with non-counseling were: maternal education below 8 years of school (PR = 1.36; 95% CI: 1.15-1.62), 0 to 3 prenatal visits (RP = 0.73; IC 95%: 0.59-0.90) and hospitals with less than 50% of the parturients submitted to the HIV rapid test (PR = 1.65; 95% CI: 1.40-1.96). Conclusion: Socially underprivileged women were not a target of counseling, and only the low number of prenatal visits proved to be a protective factor against non-counseling. Counseling was seldom practiced for HIV rapid testing, indicating that this test has been performed without the consent of women, in an imperative way. .