RESUMEN
Type F botulism was confirmed in a 54-year-old male with signs compatible with botulism who reported to the emergency unit of a hospital. Botulinal neurotoxin was detected in the patient's serum and fecal specimens, and a neurotoxigenic organism whose physiologic characteristics correspond to those of Clostridium baratii was isolated. The toxin produced by the isolate was neutralized by type F botulinal antitoxin and cross-neutralized with lower efficiency by type E antitoxin. The patient's food history was not suggestive of botulism, and it seems likely that the illness was due to colonization of the gut.
Asunto(s)
Botulismo/etiología , Clostridium/patogenicidad , Toxinas Botulínicas/aislamiento & purificación , Botulismo/clasificación , Botulismo/microbiología , Clostridium/aislamiento & purificación , Sistema Digestivo/microbiología , Humanos , Masculino , Persona de Mediana Edad , Neurotoxinas/aislamiento & purificaciónRESUMEN
In 17 previously reported cases of cladosporiosis, no reliable therapy was described, and death occurred usually within one year of diagnosis. Pretreatment isolates from our two patients were inhibited by 6.2 mug/ml and 3.1mug/ml of flucytosine, respectively. Although both patients died, postmortem examination results showed that in one patient, the fungus had been eradicated. In the other patient, C trichoides that was isolated at postmortem examination was resistant to flucytosine treatment.