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J Pediatr Endocrinol Metab ; 19(5): 757-60, 2006 May.
Artículo en Inglés | MEDLINE | ID: mdl-16789643

RESUMEN

Pancreatic tumors constitute a rare surgical problem in infancy and childhood. Insulinomas are rare in all age groups with an estimated incidence of one per 250,000 person-years and even rarer in childhood. We report a 10 year-old girl with malignant insulinoma. The presenting symptom was hypoglycemic attacks. Laboratory investigation demonstrated that the hypoglycemia was due to hyperinsulinism. MRI of the abdomen revealed a mass at the tail of the pancreas. Distal pancreatectomy with splenectomy was performed. Histological examination showed malignant insulinoma with peripancreatic lymph node metastases. One month later abdominal MRI revealed the existence of multiple small metastatic foci in the liver, which were confirmed by In111 octreoscan. Treatment with octreotide was started and the disease is stable after 12 months of therapy.


Asunto(s)
Insulinoma/patología , Neoplasias Pancreáticas/patología , Antineoplásicos Hormonales/uso terapéutico , Niño , Femenino , Humanos , Hipoglucemia/etiología , Insulinoma/diagnóstico por imagen , Neoplasias Hepáticas/secundario , Imagen por Resonancia Magnética , Octreótido/uso terapéutico , Pancreatectomía , Neoplasias Pancreáticas/diagnóstico por imagen , Cintigrafía , Esplenectomía
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