RESUMEN
The differential diagnosis of vancomycin associated renal toxicity includes acute tubular necrosis and interstitial nephritis. We report a case of vancomycin induced renal toxicity shown by Tc-99m mercaptoacetyltriglycine renal scan. Nephrotoxicity was evolved secondary to vancomycin used for treating a patient with meningitis. Tc-99m mercaptoacetyltriglycine renal scan may play a role in differentiation between acute tubular necrosis and tubulointerstitial nephritis of vancomycin associated renal toxicity and can facilitate the clinical decision making.
Asunto(s)
Antibacterianos/efectos adversos , Necrosis Tubular Aguda/diagnóstico por imagen , Nefritis Intersticial/diagnóstico por imagen , Radiofármacos , Tecnecio Tc 99m Mertiatida , Vancomicina/efectos adversos , Antibacterianos/uso terapéutico , Niño , Diagnóstico Diferencial , Humanos , Necrosis Tubular Aguda/inducido químicamente , Masculino , Meningitis/tratamiento farmacológico , Nefritis Intersticial/inducido químicamente , Cintigrafía , Vancomicina/uso terapéuticoRESUMEN
A 58 year old female was referred for FDG-PET/CT for restaging of endometrial adenocarcinoma. For evaluation of treatment, no metastases were detected on FDG-PET/CT which was performed 18 months later after the surgery. During follow-up, FDG-PET/CT was performed 6 months later than the previous FDG-PET/CT for restaging. A lesion with increased metabolic activity (SUV max: 10.21) was detected at spleen which was not seen on previous FDG-PET/CT scan. The lesion was consistent with metastasis of endometrial carcinoma. Splenic metastasis of endometrial carcinoma is extremely rare. There are only 13 cases of splenic metastasis from endometrial carcinoma that reported in the literature before. There is only one splenic metastasis of endometrial carcinoma case reported in the literature which is imaged with FDG-PET. To best of our knowledge this is the first report of solitary splenic metastasis of endometrial carcinoma that is imaged with FDG-PET/CT.