Association of Central serous chorioretinopathy with type of personality, anxiety and depression.

PURPOSE: Central serous chorioretinopathy (CSCR) a relatively common cause of visual impairment, which is characterized by subretinal fluid accumulation in the macula and is more common in middle-aged males. Various risk factors have been reported in literature, among which substantial role of psychological factors is cited. Our aim was to look for the prevalence and association of the psychiatric factors in CSCR patients and to compare them with other non-chorioretinal ocular pathologies. METHODS: A cross-sectional correlational study was undertaken involving 91 CSCR patients, along with 91 patients with other non-chorioretinal diseases. Their risk factors, clinical history, ocular examination, and psychiatric assessments were done using standardized tools, and the groups were compared in terms of scoring of Framingham Type A scale (FTAS), Hamilton Anxiety Rating Scale (HAM-A), and Hamilton Depression Rating Scale (HDRS). RESULTS: CSCR patients had a male:female ratio of 8:1. Chronic, bilateral, and recurrent diseases were found in 15%, 20%, and 23% cases, respectively. Anxiety disorder had a prevalence of 40%, followed by major depression with a prevalence of 24%, and these were significantly higher than non-chorioretinal disease patients (odds ratios 14.18 and 5.30, respectively). Also, these psychiatric disorders were significantly associated with an overall lower visual acuity and greater central macular thickness due to subretinal fluid accumulation. CONCLUSION: Psychiatric comorbidities like Type A personality trait and depression and anxiety disorders were significantly more prevalent in CSCR patients, compared to non-chorioretinal pathologies. Focus on psychological health would certainly benefit these patients in terms of better management of not only CSCR, but their psychiatric morbidity as well.

Level of Satisfaction Towards Healthcare Services in Patients Attending Psychiatry Outpatient Department of a Tertiary Care Hospital in Eastern India.

Background: Patients' satisfaction with healthcare services contributes to their compliance with the treatment and thus impacts their health. Therefore, patient satisfaction is increasingly being used as an indicator of health system performance in a country. Though several studies have been reported from different parts of India, most did not include psychiatric patients. This study assessed the level of satisfaction of psychiatric outpatients and its association with socio-demographic, hospital-related, and treatment-related variables. Methods: This cross-sectional study assessed 152 patients attending psychiatry outpatient department (OPD) of a tertiary care hospital. Treatment-related satisfaction was measured using the Short Assessment of Patient Satisfaction (SAPS) scale, and variables not related to treatment were assessed using Likert scales. Results: Most participants were satisfied with the overall cleanliness of the hospital (82.9%), the useable condition of toilets (73%), and waiting time in the OPD ticket counter, doctor's room, and pharmacy. More than 80% were pleased with the OPD staff's behavior and working efficiency. In the seven dimensions of the SAPS scale, satisfaction level was variable. Overall satisfaction with the care received in the hospital was 60.5%. Conclusions: The level of patient satisfaction is good in psychiatry OPD services of our hospital, and it depends on treatment-independent variables also. So, liaison between the medical- and non-medical-management teams is crucial to augment patient satisfaction.

Collective behavior of soft self-propelled disks with rotational inertia.

We investigate collective properties of a large system of soft self-propelled inertial disks with active Langevin dynamics simulation in two dimensions. Rotational inertia of the disks is found to favor motility induced phase separation (MIPS), due to increased effective persistence of the disks. The MIPS phase diagram in the parameter space of rotational inertia and disk softness is reported over a range of values of translation inertia and self-propulsion strength of the disks. Our analytical prediction of the phase boundary between the homogeneous (no-MIPS) and MIPS state in the limit of small and large rotational inertia is found to agree with the numerical data over a large range of translational inertia. Shape of the high density MIPS phase is found to change from circular to rectangular one as the system moves away from the phase boundary. Structural and dynamical properties of the system, measured by several physical quantities, are found to be invariant in the central region of the high density MIPS phase, whereas they are found to vary gradually near the peripheral region of the high density phase. Importantly, the width of the peripheral region near the phase boundary is much larger compared to the narrow peripheral region far away from the phase boundary. Rich dynamics of the disks inside the high density MIPS phase is addressed. Spatial correlation of velocity of the disks is found to increase with rotational inertia and disk hardness. However, temporal correlation of the disks' velocity is found to be a function of rotational inertia, while it is independent of disk softness.

Reentrant phase separation of a sparse collection of nonreciprocally aligning self-propelled disks.

We study a model of aligning self-propelled disks that nonreciprocally reorient the self-propulsion directions along the interparticle separation and towards the other disks. In the limit of small inertia and large softness, where conventional motility-induced phase separation is absent, we demonstrate that the homogeneous system at a small area fraction phase-separates into clusters and a low-density phase that, eventually, reenters the homogeneous phase with a monotonic increase in alignment strength. The disks inside the clusters move with a finite space-dependent speed, constantly shuttling between clusters through the surrounding low-density homogeneous phase while maintaining the hexatic structure properties within the clusters. The area fraction gradually increases from the periphery towards the center of the clusters with a negligible correlation of the velocity and propulsion direction inside the clusters. The novel collective behavior of reentrant phase separation is found to follow from both the limits of hard disks and extremely small inertia, tending towards the overdamped limit. However, important differences in the structural and dynamical properties are shown in the limit of hard disks and extremely small inertia, as compared to that for soft disks at finite inertia. We show that the cluster phase is associated with an effective temperature for a wide range of values of alignment strength, whereas an effective temperature is associated with the specific range of alignment in the low-density phase. We believe that the reentrant phase behavior in the limit of small area fraction and the remarkable properties of the clusters should be useful in understanding a wide range of physics issues, ranging from clogging and unclogging to information exchange and transport, in biological and synthetic self-propelled systems.

Motility-induced phase separation of self-propelled soft inertial disks.

The phase diagram of the phenomenon of motility-induced phase separation (MIPS) for a collection of self-propelled interacting disks over a large inertial range is explored using active Langevin dynamics simulation with particular emphasis on disk softness and effective size. It is shown that the parabola-like phase boundary between the homogeneous and MIPS states in the semi-log space of disk softness and effective size moves towards the hard disk limit with increase in inertia, before complete disappearance in the limit of large inertia. With increase in effective size of the disks, re-entrant phase separation, that is the system phase-separating from a homogeneous phase and eventually re-entering the homogeneous phase, is reported. The structural and the dynamical properties of the different phases are investigated in the considered inertial range. The particular shape of the phase boundary and the re-entrant behavior is explained based on several qualitative and quantitative results. Unlike most of the earlier studies on MIPS, which consider hard particle limits, our findings may be directly applicable to soft active matter for a range of physical and biological systems.

Selective synthesis of DC carbon arc-generated carbon nanotube and layered-graphene and the associated mechanism.

Herein we report how an anode is eroded and the eroded mass is deposited on the cathode surface at different arc currents ([Formula: see text]) in a DC carbon arc discharge using roughly oriented graphite (ROG) as electrodes. It was found that the nature of anode erosion critically depends on [Formula: see text] and has profound effects on the morphology of the as-synthesized cathode deposits (CDs), the conversion efficiency of the system to form the CDs and their compositions. By characterizing the as-synthesized CDs in their totality by transmission electron microscopy, Raman spectroscopy, and x-ray diffraction it was found that there exists a critical value of [Formula: see text] below which the arc remains constricted, and above which the arc becomes intense. It was further found that the system can selectively generate both carbon nanotubes (CNTs) and layered-graphene sheets (LGs) when the carbon arc runs in constricted and intense modes, respectively. By the suitable adjustment of [Formula: see text] it is possible to switchover between the aforementioned arc-modes. Based on the experimental results, a semi-empirical model encompassing the plausible effects of rapid and random movement of the anode spot on the used ROG anode surface was developed to provide new insights into the growth mechanism of arc-generated CNTs and LGs. The state-of-the-art presented in this paper could facilitate the carbon arc discharge route for the tailored synthesis of highly crystalline CNTs and LGs.

Impact of COVID-19 on Obsessive Compulsive Disorder (OCD).

Objective: Handwashing is now considered as one of the best safety measures to prevent COVID-19 infection. The effect of excessive handwashing for health on obsessive compulsive disorder (OCD) patients who are already having washing compulsion is not known. Furthermore, the fear of contamination of COVID-19 in patients who already have obsession of contamination is not known. This study aims to evaluate the effect of COVID-19 on OCD patients. Method : Phone interviews were done with 84 patients previously diagnosed with obsession of contamination and compulsive washing. Yale Brown Obsessive Compulsive Scale was used and the scores of the participants were compared to their prepandemic scores. Results: Only 5 patients (6%) had exacerbation of symptoms after the COVID-19 pandemic. Most of the patients did not report any deterioration of symptoms due to the pandemic. Conclusion: Handwashing protocol does not aggravate the washing compulsion of patients. Similarly, the fear of infection with COVID-19 does not increase their fear of contamination.

Phase transition and emergence of active temperature in an active Brownian system in underdamped background.

We explore the role of inertia in the properties of active Brownian particles (ABPs) immersed in an underdamped background in two dimensions using Langevin dynamics computer simulation. Similar to an equilibrium two-dimensional passive interacting particle system, the system of ABPs transits from a liquid phase to a solid phase with the change in the coupling parameter, which is the ratio of interaction potential energy and thermal energy of the background solvent. Important qualitative and quantitative differences are found in the liquid-solid phase transition with increasing strength of activity as compared to those found in the conventional overdamped background limit. In the underdamped background, inherent activity is found to lead to a temperature, called the active temperature and defined by average velocity fluctuations of the ABPs, that is different from the fixed background solvent temperature. A new scaling law for active temperature as a function of activity strength is found near the liquid-solid boundary. Active temperature, which behaves similar to the thermodynamic equilibrium temperature, is also found to depend upon the interaction strength between the active particles and the strength of the background dissipation. With an increase in background dissipation, the difference between active temperature and the background solvent temperature decreases and the difference is found to eventually vanish in the overdamped limit, demonstrating the correctness of the calculation.

Beneficial aspects of autism stemming from enhanced visuospatial skills: Result from a comparative study in India.

BACKGROUND: Autism spectrum disorder (ASD) is a relatively common neurodevelopmental disorder characterized by impairments in social interaction and communication, associated with restrictive and repetitive behaviors, interests, and activities. However, there are various positive character traits among individuals suffering from ASD - they are generally honest, decisive, and nonjudgmental. They are also reported to have excellent attention to details, which have been ascribed to their enhanced visual search skills. AIM: Our study was undertaken to assess these visuospatial perception skills among children with autism and compare the results with that of typically developing (TD) children in the Indian population. MATERIALS AND METHODS: A total of 47 children with ASD and 47 age-, gender-, and education-matched TD children were assessed using tests for disjunctive and conjunction search, real-world visual search, and visual working memory. RESULTS: Children with ASD performed significantly better than the TD children in tests for visual search and were comparable in the test for visual working memory. CONCLUSION: Our study showed that children with autism have enhanced visual skills, and this quality can be honed further and be utilized in jobs that require good observation skills and attention to details.

Antimicrobial properties of uncapped silver nanoparticles synthesized by DC arc thermal plasma technique.

We, herein, report the antimicrobial properties of uncapped silver nanoparticles for a Gram positive model organism, Bacillus subtilis. Uncapped silver nanoparticles have been prepared using less-explored DC arc thermal plasma technique by considering its large scale generation capability. It is observed that the resultant nanoparticles show size as well as optical property dependent antimicrobial effect.