RESUMEN
The article presents results of treatment of 78 patients with the history of coronary bypass operations for ischemic heart disease. There were 48 patients with high risk factors of the development of pyo-septic complications. Among them there were 27 patients treated by complex postoperative therapy including intravascular photomodification of blood. The intravascular irradiation of blood was shown to have a positive influence upon the development of the early postoperative period in this category of patients. The immunomodulating effect was noted due to a greater amount of activated lymphocytes and T-helpers in blood. The positive dynamics of immunological indices were in correspondence with the data of the clinical state, pyo-inflammatory complications were not registered in this group of patients. Early (on the 3rd-5th days) inclusion of the intravascular irradiation of blood in the complex postoperative therapy is thought to be expedient for the patients with high risk of pyo-inflammatory complications.
Asunto(s)
Sangre , Puente de Arteria Coronaria/efectos adversos , Fototerapia , Complicaciones Posoperatorias , Sepsis/prevención & control , Adulto , Anciano , Humanos , Activación de Linfocitos/efectos de la radiación , Masculino , Persona de Mediana Edad , Sepsis/sangre , Linfocitos T Colaboradores-Inductores/inmunología , Linfocitos T Colaboradores-Inductores/efectos de la radiaciónRESUMEN
Complexes of nucleic acids and acid nuclear proteins that are active toward human T-lymphocytes were isolated from cells of bakers' yeast Saccharomyces cerevisiae. The conditions of isolation of nucleoprotein complexes by acid extraction followed by microfiltration for concentration of macromolecular components were optimized. Gel filtration and electrophoresis were used to study the composition and molecular weights of components of the preparations obtained. It was shown that nucleoprotein complex had a molecular weight of 1430 kDa. However, only one zone was determined by electrophoresis of the protein component with a molecular weight of 30 kDa.
Asunto(s)
Proteínas Fúngicas/farmacología , Nucleoproteínas/farmacología , Linfocitos T/efectos de los fármacos , Proteínas Fúngicas/inmunología , Humanos , Activación de Linfocitos/efectos de los fármacos , Nucleoproteínas/inmunología , Saccharomyces cerevisiae , Linfocitos T/inmunologíaAsunto(s)
Transfusión de Componentes Sanguíneos/normas , Sangre/virología , Seguridad/normas , Transfusión de Componentes Sanguíneos/efectos adversos , Infecciones por Virus ADN/prevención & control , Infecciones por Virus ADN/transmisión , Virus ADN , Flaviviridae , Virus de Hepatitis , Hepatitis Viral Humana/prevención & control , Hepatitis Viral Humana/transmisión , Herpesvirus Humano 8 , Humanos , Esclerosis Múltiple/virología , Retroviridae , Infecciones por Retroviridae/prevención & control , Infecciones por Retroviridae/transmisión , Sarcoma de Kaposi/etiología , Sarcoma de Kaposi/prevención & controlRESUMEN
A 5% ointment acycloguanosine was tried in the treatment of recurrent herpes simplex of the skin and genitalia in 48 patients. The treatment brought limitation of the process, relief of the symptoms, control of local manifestations and toxicity, accelerated epithelization, complete regression and disappearance of the eruption.
Asunto(s)
Aciclovir/uso terapéutico , Antivirales/uso terapéutico , Herpes Simple/tratamiento farmacológico , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Naftoquinonas/uso terapéuticoRESUMEN
The state of upper respiratory tract, non-specific cell resistance and immune status were studied in persons who participated in liquidation of the Chernobyl APS disaster consequences. The prolonged influence of factors caused by small doses of ionizing irradiation leads to mucosa affection of upper respiratory tract, considerable reduction of phagocytic and antiviral activity of monocytes and worsening of the immune status of organism. The data obtained during researches explains the considerable increase of ARD among these persons.