Asunto(s)
Secuestro Broncopulmonar/diagnóstico , Anciano , Diagnóstico Diferencial , Femenino , HumanosRESUMEN
It is taught that, when a cervical rib is present, the subclavian vessels and brachial plexus always arch over it. The present case reemphasizes that the brachial plexus may be split by the cervical rib.
Asunto(s)
Plexo Braquial/anomalías , Costillas/anomalías , Adolescente , Humanos , Masculino , Costillas/cirugíaRESUMEN
Annular pancreas is a congenital anomaly which, though present at birth, may cause few symptoms until adulthood. A case of annular pancreas with intermittent duodenal obstruction is described in a 49-year-old alcoholic man. Few other entities cause such obstruction. In similar cases, clinical suspicion of annular pancreas may lead to prompt diagnosis and treatment.
Asunto(s)
Alcoholismo/complicaciones , Obstrucción Duodenal/etiología , Páncreas/anomalías , Anastomosis Quirúrgica , Humanos , Masculino , Persona de Mediana Edad , Páncreas/cirugía , Pancreatitis/diagnóstico , Pancreatitis/etiología , Tomografía Computarizada por Rayos XRESUMEN
Laser bronchoscopy was performed 87 times in 58 patients over a three-year period at Wilkes-Barre General Hospital. Fifty-six patients (97 percent) had malignant disease, including bronchogenic carcinoma (46), metastatic neoplasm to bronchus or lung (eight), or direct extension of esophageal carcinoma (two); benign pathology included tracheal papillomatosis (one) and granulation tissue (one). Eighty-six percent of tumors were proximally located (trachea, carina, mainstem bronchi). A standardized procedure utilizing both rigid and flexible bronchoscopy and the Nd:YAG laser was employed, with two deaths (2.3 percent) and eight complications (9.2 percent). Results were good or excellent in all five patients treated for bleeding and in 68 of 82 patients (83 percent) treated for obstruction. The patient with an obstructing or bleeding endobronchial lesion can achieve palliation through Nd:YAG laser bronchoscopic resection.
Asunto(s)
Broncoscopía , Esófago/cirugía , Terapia por Láser , Adulto , Anciano , Anciano de 80 o más Años , Neoplasias de los Bronquios/cirugía , Broncoscopía/efectos adversos , Broncoscopía/métodos , Femenino , Humanos , Terapia por Láser/efectos adversos , Terapia por Láser/métodos , Masculino , Persona de Mediana EdadRESUMEN
Seven hundred one patients with squamous cell carcinoma of the esophagus who were treated between 1950 and 1979 were retrospectively studied. The percentage of male patients decreased over the three decades (80% to 69%); the proportion of cigarette and alcohol abusers doubled. The esophageal carcinoma was located as follows: upper third, 24.7%; middle third, 52.8%, and lower third, 22.5%. There was disparity in clinical, surgical, and pathologic staging. More than two thirds of the patients thought to have stage II lesions preoperatively proved to have stage III lesions on pathologic examination; nearly one half of patients thought to have stage II disease intraoperatively were found to have pathologic stage III lesions. This "upgrading" of stage was chiefly a result of histologic recognition of nodal metastasis or extension of carcinoma into surrounding tissues. Operation was performed in 411 cases (58.6%) and resection was performed in 261 (37.2% overall). The postoperative death rate after resection fell from 30.5% in the 1950s to 10.4% in the 1970s, with respiratory complications the predominant cause of death. Analyses were based on treatment directed at the carcinoma itself: radiotherapy, 340 cases (48.5%); resection, 176 cases (25.1%); resection plus radiotherapy, 85 cases (12.1%); no definitive treatment, 100 cases (14.3%). Overall survival for the 701 patients was 13% at 2 years and 6% at 5 years (mean survival, 16.4 months); this did not differ by decade. Survival clearly differed by treatment (p = 0.001); resection plus radiotherapy provided the best survival (35% at 2 years; 20% at 5 years; mean of 32.5 months) followed by resection (18% at 2 years; 7% at 5 years; mean of 17.5 months), radiotherapy (9% at 2 years; 3% at 5 years; mean of 12.7 months), and no treatment (0% at 2 years; 0% at 5 years; mean of 2.5 months). Survival in patients who did not have resection did not differ by decade but survival in patients with resections improved in the last two decades. Patients with pathologic stage II lesions had greatly improved survival (54% at 2 years; 25% at 5 years; mean of 42.7 months) compared with patients with stage III disease (12% at 2 years; 6% at 5 years; (mean of 15.1 months) (p = 0.001).
Asunto(s)
Carcinoma de Células Escamosas/terapia , Neoplasias Esofágicas/terapia , Adulto , Anciano , Anciano de 80 o más Años , Alcoholismo/epidemiología , Boston , Carcinoma de Células Escamosas/diagnóstico , Carcinoma de Células Escamosas/mortalidad , Carcinoma de Células Escamosas/secundario , Terapia Combinada , Neoplasias Esofágicas/mortalidad , Neoplasias Esofágicas/patología , Femenino , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Recurrencia Local de Neoplasia , Estadificación de Neoplasias , Complicaciones Posoperatorias , Estudios Retrospectivos , Fumar/epidemiología , Tasa de SupervivenciaRESUMEN
Cutaneous metastasis from lung cancer is rare, but physicians should understand its significance. We treated eight such patients during a 30-month period at Wilkes-Barre (Pa) General Hospital. The seven men and one woman ranged in age from 46 to 72 years (mean, 59 years). In three, the skin lesion was the first manifestation of the underlying cancer and in another three, it was found coincident with the lung mass. Pathologic findings included small-cell undifferentiated carcinoma in four patients, squamous cell carcinoma in three patients, and large-cell undifferentiated carcinoma in one patient. Seven of the eight primary lung lesions were in the upper lobes. Six patients had clinically occult visceral metastases at the time of skin biopsy. Only one patient survived more than six months following skin metastasis. Biopsy specimens must be taken from all new skin lesions, particularly in patients who smoke or who already have a history of lung cancer.
Asunto(s)
Carcinoma/secundario , Neoplasias Pulmonares , Neoplasias Cutáneas/secundario , Anciano , Carcinoma de Células Pequeñas/secundario , Carcinoma de Células Escamosas/secundario , Femenino , Humanos , Masculino , Persona de Mediana EdadRESUMEN
Surgical problems do not end on a person's centennial, and as our overall population ages, physicians will see increasing numbers of these most senior citizens requiring surgery. Accordingly, the records of all century-old patients who have undergone surgery at the Massachusetts General Hospital in the years 1979 to 1983 were reviewed. Three men and three women ranged in age from 100 to 104 years at the time of surgery. One patient experienced complications, but all survived their operation and lived one to two years afterward. The centenarian has already been tested by life and found exceptionally fit. Selectivity and meticulous attention to detail remain paramount in treating these patients, but elective surgery should not be deferred, nor emergency surgery denied the centenarian on the basis of chronologic age.
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Procedimientos Quirúrgicos Operativos , Anciano , Amputación Quirúrgica , Enfermedades del Sistema Digestivo/cirugía , Femenino , Estudios de Seguimiento , Hernia Inguinal/cirugía , Fracturas de Cadera/cirugía , Humanos , Masculino , Marcapaso Artificial , Aptitud Física , Complicaciones PosoperatoriasRESUMEN
The literature on substernal goiter from the seventeenth century to the present is reviewed. Substernal goiter may be defined as any thyroid enlargement that has its greater mass inferior to the thoracic inlet. Truly ectopic mediastinal goiters are rare, and most substernal goiters arise from and maintain some attachment to the cervical thyroid gland. Patients are generally in the fifth decade of life, and women predominate. Most patients experience dyspnea, stridor, or dysphagia, but 15 to 50% are asymptomatic; symptoms are often positional, and acute stridor may occur. Ten to twenty percent have no cervical mass or tracheal deviation on examination, and virtually all patients are euthyroid. Standard chest roentgenograms are often diagnostic, but computed tomographic or radioactive iodine scans may be helpful. The presence of a substernal goiter in all but the highest-risk patients is an indication for resection, usually through a cervical collar incision; an occasional patient will require sternotomy or thoracotomy. Death or major complications should be rare postoperatively. Substernal goiters are adenomatous and benign, but carcinoma occurs in 2 to 3% and may be occult. Patients should be followed closely, as these goiters may recur.
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Bocio Subesternal , Adolescente , Adulto , Anciano , Femenino , Bocio Subesternal/diagnóstico , Bocio Subesternal/etiología , Bocio Subesternal/historia , Bocio Subesternal/cirugía , Bocio Subesternal/terapia , Historia del Siglo XIX , Historia del Siglo XX , Humanos , Masculino , Métodos , Persona de Mediana Edad , Complicaciones Posoperatorias , Pruebas de Función de la TiroidesRESUMEN
Eighty patients at the Massachusetts General Hospital underwent resection of substernal goiter in the years 1976 to 1982. Mean age of the 50 women and 30 men was 56 years, and 10 (19 percent) had undergone prior thyroid surgery. The most common symptoms were cervical mass (69 percent), dysphagia (33 percent), and dyspnea (28 percent); 13 percent were asymptomatic. On examination, cervical mass was present in most (90 percent) but not all patients, 51 percent were obese, and more than one third had tracheal deviation. Fifty-one of 52 patients tested were euthyroid and one was mildly hypothyroid. Chest radiographs showed tracheal deviation in 79 percent and soft tissue mass in 56 percent. Seventy-eight patients underwent resection through a cervical collar incision only; one had cervical incision plus upper partial sternotomy; and one required cervical incision plus full median sternotomy. Pathologic examination revealed multinodular goiter in 41 (51 percent), follicular adenoma in 35 (44 percent), and Hashimoto's thyroiditis in 4 (5 percent). Mean goiter weight was 104 g, and the mean greatest dimension was 9 cm. Occult papillary carcinoma was found in two patients. There were no deaths or major complications. Analysis of our data indicate the following: (1) Substernal goiter may exist in the absence of symptoms or signs. (2) Extensive radiologic evaluation and thyroid function testing are rarely required. (3) With rare exceptions, substernal goiter represents an extension of a cervical growth through the thoracic inlet and can be approached through a cervical collar incision. (4) Histologically, these are multinodular goiters or follicular adenomas, although Hashimoto's thyroiditis may occur. (5) Given the small but present risks of acute stridor or occult malignancy and the negligible surgical risk, operation should be recommended. (6) Patients should be followed since, with or without levothyroxine, goiters may recur.
Asunto(s)
Bocio Subesternal/cirugía , Adulto , Anciano , Carcinoma Papilar/patología , Carcinoma Papilar/cirugía , Femenino , Estudios de Seguimiento , Bocio Subesternal/patología , Bocio Subesternal/fisiopatología , Humanos , Masculino , Persona de Mediana Edad , Examen Físico , Radiografía Torácica , Riesgo , Pruebas de Función de la Tiroides , Glándula Tiroides/patología , Neoplasias de la Tiroides/patología , Neoplasias de la Tiroides/cirugíaRESUMEN
Evidence mounts favoring the relationship, albeit unexplained, between Clostridium septicum infection and malignancy, particularly hematologic or intestinal malignancy. Seven patients with C. septicum gangrene or sepsis have been treated at the Massachusetts General Hospital in the years 1977-79. All of these patients have had associated malignant disease: four patients had colon adenocarcinomas, two patients had acute myeloblastic leukemias, and one patient had breast carcinoma. In six of the seven patients, the malignancy was in an advanced state; the breast carcinoma showed no evidence of recurrence after mastectomy, 17 years earlier. A bowel portal of entry is postulated in five patients. Despite prompt use of appropriate antibiotics, the only survivors were two of the four patients who underwent early extensive debridement. These results suggest that, in the patient with C. septicum infection, malignancy should be sought; that, in the septic patient with known malignancy, C. septicum should be considered; and that, in the absence of external source in the patient with clostridial myonecrosis or sepsis, the cecum or distal ileum should be considered a likely site of infection. Increased awareness of this association between C. septicum and malignancy, and aggressive surgical treatment, may result in improvement in the present 50-70% mortality rate.
Asunto(s)
Infecciones por Clostridium/complicaciones , Neoplasias/complicaciones , Adulto , Anciano , Neoplasias de la Mama/complicaciones , Infecciones por Clostridium/terapia , Neoplasias del Colon/complicaciones , Femenino , Gangrena Gaseosa/complicaciones , Humanos , Leucemia/complicaciones , Masculino , Persona de Mediana EdadRESUMEN
Two cases are presented of severe tracheal damage secondary to low-pressure high-volume endotracheal tube cuffs monitored carefully against over-inflation. Our patients' findings suggest that in the presence of tracheal inhalation injury or severe tracheal infection strict monitoring of pressures, though essential, does not preclude tracheal trauma from a low-pressure cuff, trauma to a degree generally ascribed only to high-pressure "stiff" cuffs. There is probably no arbitrarily safe level of cuff pressure in these patients; any amount of pressure is likely to further harm the tracheal wall and must be weighed into the risk-benefit equation for prolonged intubation.