RESUMEN
Patients with systemic amyloidosis often have symptoms related to impared gastrointestinal motility due to delayed gastric emptying, which results from autonomic nerve or smooth muscle infiltration with amyloid. There is no current report about gastric delaying secondary to amyloidosis due to familial Mediterranean fever. In this report, we have described a renal transplant recipient with delayed gastric emptying secondary to amyloidosis due to familial Mediterranean fever, which improved with erithromycin treatment.
Asunto(s)
Fiebre Mediterránea Familiar/complicaciones , Vaciamiento Gástrico , Fallo Renal Crónico/cirugía , Trasplante de Riñón , Adulto , Amiloidosis/etiología , Fiebre Mediterránea Familiar/fisiopatología , Humanos , Fallo Renal Crónico/etiología , Masculino , Resultado del TratamientoRESUMEN
The authors describe a 38-year-old man who was referred to the nuclear medicine department because of pain and swelling of his fingers in both hands. Tc-99m MDP and Tl-201 scans were performed to evaluate the lesions. A Tc-99m MDP bone scan showed hyperemia and increased uptake in the lesions. A Tl-201 scan showed marked uptake in both early and delayed images in the lesions of his fingers. Bone biopsy and histologic examination confirmed sarcoidosis. This case indicates that Tl-201 uptake can be seen in bone lesions resulting from sarcoidosis.
Asunto(s)
Enfermedades Óseas/diagnóstico por imagen , Enfermedades del Tejido Conjuntivo/diagnóstico por imagen , Sarcoidosis/diagnóstico por imagen , Sarcoidosis/patología , Radioisótopos de Talio/farmacocinética , Adulto , Biopsia con Aguja , Enfermedades Óseas/patología , Enfermedades del Tejido Conjuntivo/patología , Mano/diagnóstico por imagen , Humanos , Masculino , Cintigrafía , Sensibilidad y Especificidad , Medronato de Tecnecio Tc 99mRESUMEN
The authors present a comparison of the findings for thallium-201 (Tl-201), Tc-99m MAG3 and Tc-99m MDP in subacute and chronic radiation nephritis in a 9-yr-old boy who was treated by radiation therapy for alveolar rhabdomyosarcoma of the left chest wall by a radiation port that partially included the left kidney. Tl-201 imaging three and six months later showed a cortical defect in the left kidney due to radiation nephritis. Tc-99m MDP scan showed increased uptake on both occasions, but more marked in the subacute period than in the chronic period. Tc-99m MAG3 showed decreased concentration and increased cortical retention three months later. Six months after the radiation therapy, a cortical defect corresponding to the cortical area that showed increased parenchymal retention was more prominent in the Tc-99m MAG3 scan. In the present case, Tc-99m MDP, Tl-201 and Tc-99m MAG3 findings may provide useful information for understanding pathophysiological damage in the kidney after radiation.