Vaginal fluid pH, cervicovaginitis and cervical length in pregnancy.

AIM: The purpose of this prospective study was to determine the possible association among vaginal fluid pH, cervicovaginitis and cervical length in singleton pregnancies at 16-22 weeks of gestation. METHODS: A total of 240 asymptomatic singleton pregnancies at 16-22 weeks of gestation were included to the study. Vaginal fluid pH was determined using pH paper in a sterile speculum examination, and cervical length was examined by transvaginal ultrasonographic measurement. Vaginitis was diagnosed by pH determination and wet mount smear; cervicitis was diagnosed by cervical examination. Patients were followed to delivery and hospital records were reviewed to extract obstetric information. Preterm delivery was defined as delivery at or prior to 36 weeks of gestation. Abnormal pH was defined as a pH of > 5.0. Patients with cervicovaginitis (n = 72) were compared with those without any trace of infection (n = 60). RESULTS: The mean gestational age was 20.3 +/- 1.4. We found an significant association among cervicovaginitis, cervical length and vaginal pH. There was a significant correlation between an elevated vaginal pH (> 5.0) and a shortened cervical length (r = -0.59, p < 0.001). Vaginal fluid pH > 5.0 was associated with increased risk of preterm delivery (OR 4.3, 95% CI 2.0, 9.3; p = 0.001) as well as delivering an infant of less than 2,500 g (OR 4.0, 95% CI 1.4, 11.0; p = 0.009). CONCLUSIONS: Elevated vaginal fluid pH in women at 16-22 weeks of gestation seems to be associated with a decreased cervical length and increased risk of preterm delivery.

Evaluation of LOOP electrosurgical excisional procedure: case series.

OBJECTIVE: To evaluate the loop electrosurgical excisional procedure (LEEP) which is performed to treat high-grade cervical intraepithelial lesions (HGSIL). MATERIAL AND METHODS: Twenty-one cases diagnosed as LGSIL and HGSIL after histopathological examination were included in the study among patients who had cervical colposcopy-directed biopsies after an abnormal cytology report at Ege University School of Medicine, Obstetrics and Gynecology Department between the years of 2007 and 2009. The patients underwent LEEP or LEEP-cone procedures. RESULTS: The patients with cervical smear results of ten ASCUS, eight LGSIL, and three HGSIL underwent colposcopy-guided punch biopsies. Those with the result of CIN 1 and CIN 2 underwent LEEP or LEEP-cone procedures. Pathologic examination correlated with biopsy results and surgical margins were all negative. All patients were followed-up with cervical cytology. CONCLUSION: LEEP and LEEP-cone procedures are therapeutic procedures in cervical intraepithelial lesions.

Abdominal skin metastasis of endometrial adenocarcinoma: case report.

Skin metastasis from endometrial adenocarcinoma in the radiotherapy field is reported. A 60-year-old woman with FIGO stage IB, grade 2 endometrial adenocarcinoma presented 24 months after initial surgery with skin metastasis located on the abdomen.