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1.
J Clin Med ; 13(7)2024 Apr 05.
Artículo en Inglés | MEDLINE | ID: mdl-38610879

RESUMEN

Background: Skin injuries often affect the sports community. Almost every type of athletic activity is associated with traumatic skin injuries, such as surface wounds, bruising, abrasions, subcutaneous hematomas, blunt trauma, nail injuries, friction burns, and blisters. Methods: The aim of this study was to assess the rates, location sites, and seasons of appearance of skin injuries in beach volleyball athletes in Greece. Seven hundred and eighty-five beach volleyball athletes participated in this study. The average age was 28.4 years. Skin injuries included superficial wounds (erosions, incisions, lacerations), deep wounds, hematomas, nail lacerations, friction burns, and friction blisters. The recorded variables encompassed gender, age, the time of year when athletes might be at higher risk of injuries, and the specific body regions affected. Additionally, data regarding training details such as years of practice, weekly training frequency, and daily training duration were also documented. Results: Incidence rates correlated to gender: (a) superficial wounds (p < 0.001), (b) years of training: hematomas (p < 0.001), and (c) average hours of daily training: superficial wounds (p < 0.001), deep wounds (p < 0.001), and friction blisters (p < 0.001). Conclusions: Although early detection, recognition, and treatment are essential, the prevention of skin injuries can also be linked to health and athletic performance.

2.
J Sports Med Phys Fitness ; 64(5): 496-503, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38385636

RESUMEN

BACKGROUND: Athletes participating in outdoor sports are in a high-risk category for prolonged sun exposure. This study investigates whether swimmers and beach volleyball athletes adopt appropriate measures to protect their skin from the sun. Sunscreens play a key role in protecting the skin from solar radiation and preventing premature aging. The study assesses the frequency of sunscreen use and the incidence of sunburn among athletes. METHODS: Athletes completed a self-administered questionnaire regarding their sun protection and exposure habits. Participants aged 9 to 60 years, engaged in swimming (N.=1047) and beach volleyball (N.=785), were included in this study. RESULTS: In the group of swimmers (N.=858), a notable percentage never used sunscreen, and among those who did, (N.=137), natural products were predominantly applied. Gender differences revealed a significantly higher sunscreen usage (P<0.001) among female swimmers compared to males. Among beach volleyball athletes, sunscreen use was notably higher (90%), with 55.6% applying natural sunscreen and 44.4% opting for non-natural alternatives. Regarding the incidence of sunburn, the occurrence among both male and female swimmers was observed to be very low. Among those with sunburn, females exhibited a significantly higher frequency than males (P<0.001). Conversely, in beach volleyball athletes, sunburn affected a higher percentage of males (49.8%) than females (43.9%). CONCLUSIONS: Sunscreen utilization is notably insufficient among athletes, reflecting a limited awareness of the potential risks associated with sun exposure, even though they frequently suffer from sunburn. This heightened susceptibility places them at an increased risk of developing skin lesions. Initiating and disseminating awareness campaigns that specifically emphasize the importance of sunscreen use within the outdoor sports community is imperative.


Asunto(s)
Quemadura Solar , Protectores Solares , Natación , Voleibol , Humanos , Protectores Solares/administración & dosificación , Quemadura Solar/epidemiología , Quemadura Solar/prevención & control , Femenino , Masculino , Adolescente , Estudios Transversales , Grecia/epidemiología , Niño , Adulto , Adulto Joven , Persona de Mediana Edad , Atletas/estadística & datos numéricos , Prevalencia , Encuestas y Cuestionarios , Factores Sexuales
3.
Front Bioeng Biotechnol ; 10: 820196, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35497367

RESUMEN

Quantification of natural knee kinematics is essential for the assessment of joint function in the diagnosis of pathologies. Combined measurements of tibiofemoral and patellofemoral joint kinematics are necessary because knee pathologies, such as progression of osteoarthritis and patellar instability, are a frequent concern in both articulations. Combined measurement of tibiofemoral and patellofemoral kinematics also enables calculation of important quantities, specifically patellar tendon angle, which partly determines the loading vector at the tibiofemoral joint and patellar tendon moment arm. The goals of this research were to measure the differences in tibiofemoral and patellofemoral kinematics, patellar tendon angle (PTA), and patellar tendon moment arm (PTMA) that occur during non-weight-bearing and weight-bearing activities in older adults. METHODS: High-speed stereo radiography was used to measure the kinematics of the tibiofemoral and patellofemoral joints in subjects as they performed seated, non-weight-bearing knee extension and two weight-bearing activities: lunge and chair rise. PTA and PTMA were extracted from the subject's patellofemoral and tibiofemoral kinematics. Kinematics and the root mean square difference (RMSD) between non-weight-bearing and weight-bearing activities were compared across subjects and activities. RESULTS: Internal rotation increased with weight-bearing (mean RMSD from knee extension was 4.2 ± 2.4° for lunge and 3.6 ± 1.8° for chair rise), and anterior translation was also greater (mean RMSD from knee extension was 2.2 ± 1.2 mm for lunge and 2.3 ± 1.4 mm for chair rise). Patellar tilt and medial-lateral translation changed from non-weight-bearing to weight-bearing. Changes of the patellar tendon from non-weight-bearing to weight-bearing were significant only for PTMA. CONCLUSIONS: While weight-bearing elicited changes in knee kinematics, in most degrees of freedoms, these differences were exceeded by intersubject differences. These results provide comparative kinematics for the evaluation of knee pathology and treatment in older adults.

4.
Viruses ; 13(11)2021 10 20.
Artículo en Inglés | MEDLINE | ID: mdl-34834914

RESUMEN

Viral skin infections often affect the sports community. The aim of this study was to assess the rates, location sites, and seasons of appearance of common viral cutaneous diseases in beach volleyball athletes in Greece. Five hundred and forty-nine beach volleyball athletes participated in this study. The average age was 28.4 years. The viral infections were herpes simplex (type 1), molluscum contagiosum and warts. The measured parameters included: gender, age, the season when athletes may be more susceptible to infections and the location of infection in the body. Practicing information such as the number of training years, number of weekly trainings, and average hours of daily training was also recorded. Incidence rates correlated in relation to age: (a) warts (p < 0.001), molluscum contagiosum (p < 0.001), and herpes simplex (p = 0.001); (b) years of training: warts (p < 0.001), molluscum contagiosum (p < 0.001), and herpes simplex (p = 0.004); (c) average hours of daily training: molluscum contagiosum (p = 0.006) and herpes simplex (p < 0.010). The skin is the largest organ, and the risk of infection should not be underestimated. Prevention, early detection, recognition, and treatment are related to health and athletic performance, but also to the risk of transmission.


Asunto(s)
Atletas/estadística & datos numéricos , Herpes Simple/epidemiología , Molusco Contagioso/epidemiología , Virus del Molusco Contagioso/aislamiento & purificación , Enfermedades de la Piel/epidemiología , Verrugas/epidemiología , Adulto , Femenino , Grecia/epidemiología , Herpes Simple/virología , Humanos , Masculino , Molusco Contagioso/virología , Virus del Molusco Contagioso/clasificación , Virus del Molusco Contagioso/genética , Virus del Molusco Contagioso/fisiología , Filogenia , Simplexvirus/genética , Simplexvirus/aislamiento & purificación , Simplexvirus/fisiología , Enfermedades de la Piel/virología , Voleibol , Verrugas/virología , Adulto Joven
5.
Knee ; 29: 86-94, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-33582595

RESUMEN

BACKGROUND: The objective of this study was to discover whether notable differences in mobile and fixed-bearing kinematics occur during activity that promotes tibial rotation, and to compare these results with normal healthy kinematics. We hypothesized that rotating-platform knee replacements would exhibit greater rotation of the tibia relative to the fixed-bearing knee replacements. MATERIALS AND METHODS: The in vivo motion of the tibia relative to the femur was measured in subjects with posterior stabilized fixed-bearing (FB) and rotating-platform (RP) total knee arthroplasties using a high-speed stereo radiography system during a lunge and gait with a change in direction (pivot). RESULTS: The in vivo internal/external (IE) rotation and anterior/posterior translation of the tibia relative to the femur was similar between mobile and fixed-bearing total knee prostheses during two activities of daily living that included an activity that challenged tibial IE rotation. Measurements of IE rotation in participants with RP had higher variability and significantly greater range between maximum internal and external rotation compared with FB participants. The greater amount of variability of RP was not unlike the healthy knee. CONCLUSION: The pattern of IE rotation and AP translation for both RP and FB designs were similar to healthy kinematics but with less IE rotation. The RP implants more closely replicated the asymmetrical posterior condylar translation and range of IE rotation of the healthy knee during activity that challenged tibial IE rotation.


Asunto(s)
Artroplastia de Reemplazo de Rodilla , Análisis de la Marcha , Articulación de la Rodilla/diagnóstico por imagen , Articulación de la Rodilla/fisiología , Prótesis de la Rodilla , Rotación , Femenino , Humanos , Masculino , Persona de Mediana Edad , Diseño de Prótesis , Radiografía
6.
Hum Mov Sci ; 75: 102746, 2021 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-33378727

RESUMEN

The patellofemoral (PF) joint is susceptible to many pathologies resulting from acute injury, chronic disease and complications following surgical treatment of the knee. The objectives of this study were to describe case series measurements of patellar motion in healthy older adults as they performed three gait activities, determine patellar tendon angle and moment arm, and show if these quantities were activity dependent. A stereo radiography system was utilized to obtain the 3D PF kinematics of seventeen healthy people over 55 years of age (8F/9M, 66 ± 7.9 years old, 75.7 ± 20.5 kg) as they performed level walking, a step down, and a pivot turn. For a similar portion of the gait cycle, patellar flexion (6.2° ± 5.8) and average range of motion (ROM) (11.0° ± 5.9°) for walking with a step down was greater compared to the other gait activities (gait ROM 6.9° ± 4.3°, pivot ROM 5.7° ± 3.3°), while the average range of motion for patella tilt was greater during walking with a pivot turn (8.6° ± 3.9°). However, each subject displayed distinct PF kinematic trends during all activities with a few notable exceptions. Importantly, the knee extensor mechanism characteristics of patellar tendon angle and moment arm showed considerable variation across subjects but were largely unaltered by changing activities. The variation between subjects and the different behavior of the patella during the step down and pivot emphasized the need for analysis of a range of activities to reveal individual response to pathology and treatment in patellar maltracking and osteoarthritis.


Asunto(s)
Marcha/fisiología , Articulación de la Rodilla/fisiología , Rótula/cirugía , Articulación Patelofemoral/fisiología , Anciano , Artroplastia de Reemplazo de Rodilla , Fenómenos Biomecánicos , Femenino , Humanos , Rodilla/fisiología , Masculino , Persona de Mediana Edad , Osteoartritis/fisiopatología , Ligamento Rotuliano/fisiopatología , Ligamento Rotuliano/cirugía , Rango del Movimiento Articular , Caminata/fisiología
7.
J Cosmet Dermatol ; 19(9): 2165-2168, 2020 09.
Artículo en Inglés | MEDLINE | ID: mdl-32475018

RESUMEN

BACKGROUND: Epidemics are a major cause of health problems in developing countries, preventing the accumulation of human capital and economic growth. On the appearance of the pandemic of the new coronavirus COVID-19 worldwide, this survey was carried out in the 4th week of the occurrence of the cases in Greece. OBJECTIVES: The investigation was aimed at the social and economic impact caused by this COVID-19 pandemic and the state's decision to suspend the operation of businesses and stores in Greece. MATERIALS AND METHODS: One hundred and fifty-eight esthetic centers from various areas of Greece were participated in this study, and the questionnaires were sent electronically to the business owners. Statistical analyzes were conducted using Google Forms and the questionnaires analyzed through PSPP software. RESULTS: Based on their answers and the statistical analyzes, it was calculated the reduction of the monthly income for the first month of suspension of the operation of their companies. Additionally, social-related matters were examined as, how they experience this period, psychologically, financially, what problems they believe that they will face, and what changes in their work that could result from the pandemic. DISCUSSION: There is no similar study and experience for esthetic centers from a viral pandemic in literature. The suspension of operations provoked serious financial problems and significant psychological burden about what "tomorrow will bring" with returning to "normalcy."


Asunto(s)
Industria de la Belleza/economía , Industria de la Belleza/estadística & datos numéricos , COVID-19/economía , COVID-19/epidemiología , Pandemias/economía , Actitud , COVID-19/prevención & control , Regulación Gubernamental , Grecia/epidemiología , Humanos , Pandemias/legislación & jurisprudencia , Pandemias/prevención & control , SARS-CoV-2 , Estrés Psicológico/etiología , Encuestas y Cuestionarios
8.
Artículo en Inglés | MEDLINE | ID: mdl-30987087

RESUMEN

A large part of research using questionnaires for female university students relies on self-reported body mass, height, and body mass index (BMI) data; however, the validity of these data in this population group is unknown. Therefore, the aim of the present study is to examine the validity of self-reported body mass, height, and BMI in female students. Female students of biomedical sciences (n = 93, age 21.8 ± 4.7 years, height 1.63 ± 0.06 m, weight 60.5 ± 11.9 kg, and BMI 22.7 ± 3.8 kg/m²) completed the short version of the International Physical Activity Questionnaire and were tested for anthropometric characteristics at three different times of the day (12-2 p.m., n = 36; 2-4 p.m., n = 20; 4-6 p.m., n = 37). Participants over-reported height (+0.01 ± 0.02 m, +0.9 ± 1.2%, Cohen's d = 0.22) and under-reported weight (-0.8 ± 2.1 kg, -1.2 ± 3.6%, d = -0.07) and BMI (-0.7 ± 1.0 kg/m², -2.9 ± 4.2%, d = -0.19) (p < 0.001). A moderate main effect of time of day on %Δweight (p = 0.017, η² = 0.086) and %ΔBMI (p = 0.045, η² = 0.067), but not on %Δheight (p = 0.952, η² = 0.001), was observed, where the group tested at 4-6 p.m. under-reported weight and BMI more than the 2-4 p.m. group. The weekly metabolic equivalent (MET) × min did not correlate with %Δheight (r = 0.06, p = 0.657), but its correlations with %Δweight (r = -0.27, p = 0.051) and %ΔBMI (r = -0.238, p = 0.089) reached statistical significance. Participants in the early follicular phase reported BMI more accurately (p = 0.084, d = 0.68) than those in the mid-luteal phase. In conclusion, female students over-reported height and under-reported weight and BMI. Under-reporting weight and BMI is influenced by time of day and menstrual cycle phase. These findings should be considered by health professionals and researchers when administering questionnaires to female students.


Asunto(s)
Estatura , Imagen Corporal , Índice de Masa Corporal , Peso Corporal , Ejercicio Físico/psicología , Autoinforme/estadística & datos numéricos , Adolescente , Adulto , Antropometría , Femenino , Humanos , Ciclo Menstrual , Estudiantes , Encuestas y Cuestionarios , Adulto Joven
9.
Ann Biomed Eng ; 46(11): 1806-1815, 2018 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-29948373

RESUMEN

Movement of the marker positions relative to the body segments obscures in vivo joint level motion. Alternatively, tracking bones from radiography images can provide precise motion of the bones at the knee but is impracticable for measurement of body segment motion. Consequently, researchers have combined marker-based knee flexion with kinematic splines to approximate the translations and rotations of the tibia relative to the femur. Yet, the accuracy of predicting six degree-of-freedom joint kinematics using kinematic splines has not been evaluated. The objectives of this study were to (1) compare knee kinematics measured with a marker-based motion capture system to kinematics acquired with high speed stereo radiography (HSSR) and describe the accuracy of marker-based motion to improve interpretation of results from these methods, and (2) use HSSR to define and evaluate a new set of knee joint kinematic splines based on the in vivo kinematics of a knee extension activity. Simultaneous measurements were recorded from eight healthy subjects using HSSR and marker-based motion capture. The marker positions were applied to three models of the lower extremity to calculate tibiofemoral kinematics and compared to kinematics acquired with HSSR. As demonstrated by normalized RMSE above 1.0, varus-valgus rotation (1.26), medial-lateral (1.26), anterior-posterior (2.03), and superior-inferior translations (4.39) were not accurately measured. Using kinematic splines improved predictions in varus-valgus (0.81) rotation, and medial-lateral (0.73), anterior-posterior (0.69), and superior-inferior (0.49) translations. Using splines to predict tibiofemoral kinematics as a function knee flexion can lead to improved accuracy over marker-based motion capture alone, however this technique was limited in reproducing subject-specific kinematics.


Asunto(s)
Actividades Cotidianas , Articulación de la Rodilla/diagnóstico por imagen , Articulación de la Rodilla/fisiología , Modelos Biológicos , Análisis Radioestereométrico , Anciano , Fenómenos Biomecánicos , Femenino , Humanos , Masculino , Persona de Mediana Edad
10.
Med Sci Sports Exerc ; 49(11): 2260-2267, 2017 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-28614195

RESUMEN

PURPOSE: Quantification of knee motion is essential for assessment of pathologic joint function, such as tracking osteoarthritis progression and evaluating outcomes after conservative or surgical treatment, including total knee arthroplasty. Our purpose was to establish a useful baseline for the kinematic envelope of knee motion in healthy older adults performing movements of daily living. METHODS: A high-speed stereo radiography system was used to measure the three-dimensional tibiofemoral kinematics of eight healthy people over 55 yr of age (4 women/4 men; age, 61.7 ± 5.4 yr; body mass, 74.6 ± 7.7 kg; body mass index, 26.7 ± 4.4 kg·m; height, 168.2 ± 13.7 cm) during seated knee extension, level walking, pivoting, and step descent. RESULTS: Internal-external and varus-valgus rotation and anterior-posterior range of motion through stance in normal walking averaged 3.6° ± 1.1°, 2.3° ± 0.6°, and 3.4 ± 1.57 mm, respectively. Average range of motion across subjects was greater during the step-down in both internal-external rotation (average, 6.5° ± 3.1°) and anterior-posterior translation (average, 4.5 ± 1.1). Average internal-external range of motion increased to 13.5° ± 3.6° during pivoting. Range of motion of the knee in varus-valgus rotation was nearly the same for each subject across activities, rarely exceeding 6°. CONCLUSIONS: Pivoting and step descending during walking had greater internal-external rotation and anterior-posterior translation than normal gait. Internal-external rotation and anterior-posterior translation were shown to have greater activity dependence, whereas varus-valgus rotation was consistent across activities. These results were similar to prior measurements in younger cohorts, though a trend toward reduced range of motion in the older adults was observed.


Asunto(s)
Actividades Cotidianas , Rodilla/fisiología , Fenómenos Biomecánicos , Índice de Masa Corporal , Femenino , Humanos , Imagenología Tridimensional , Rodilla/diagnóstico por imagen , Masculino , Persona de Mediana Edad , Radiografía/métodos , Rango del Movimiento Articular , Rotación , Subida de Escaleras/fisiología , Caminata/fisiología
11.
Ann Biomed Eng ; 45(3): 789-798, 2017 03.
Artículo en Inglés | MEDLINE | ID: mdl-27620064

RESUMEN

Quantification of muscle moment arms is important for clinical evaluation of muscle pathology and treatment, and for estimating muscle and joint forces in musculoskeletal models. Moment arms estimated with musculoskeletal models often assume a default motion of the knee derived from measurements of passive cadaveric flexion. However, knee kinematics are unique to each person and activity. The objective of this study was to estimate moment arms of the knee muscles with in vivo subject- and activity-specific kinematics from seven healthy subjects performing seated knee extension and single-leg lunge to show changes between subjects and activities. 3D knee motion was measured with a high-speed stereo-radiography system. Moment arms of ten muscles were estimated in OpenSim by replacing the default knee motion with in vivo measurements. Estimated inter-subject moment arm variability was similar to previously reported in vitro measurements. RMS deviations up to 9.0 mm (35.2% of peak value) were observed between moment arms estimated with subject-specific knee extension and passive cadaveric motion. The degrees of freedom that most impacted inter-activity differences were superior/inferior and anterior/posterior translations. Musculoskeletal simulations used to estimate in vivo muscle forces and joint loads may provide significantly different results when subject- and activity-specific kinematics are implemented.


Asunto(s)
Rodilla/fisiología , Modelos Biológicos , Movimiento/fisiología , Músculo Esquelético/fisiología , Anciano , Fenómenos Biomecánicos , Femenino , Humanos , Masculino , Persona de Mediana Edad
12.
Med Phys ; 38(9): 4982-93, 2011 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-21978042

RESUMEN

PURPOSE: Modern HDR brachytherapy treatment for prostate cancer based on the 3D ultrasound (U/S) plays increasingly important role. The purpose of this study is to investigate possible patient movement and anatomy alteration between the clinical image set acquisition, made after the needle implantation, and the patient irradiation and their influence on the quality of treatment. METHODS: The authors used 3D U/S image sets and the corresponding treatment plans based on a 4D-treatment planning procedure: plans of 25 patients are obtained right after the needle implantation (clinical plan is based on this 3D image set) and just before and after the treatment delivery. The authors notice the slight decrease of treatment quality with increase of time gap between the clinical image set acquisition and the patient irradiation. 4D analysis of dose-volume-histograms (DVHs) for prostate: CTV1 = PTV, and urethra, rectum, and bladder as organs at risk (OARs) and conformity index (COIN) is presented, demonstrating the effect of prostate, OARs, and needles displacement. RESULTS: The authors show that in the case that the patient body movement/anatomy alteration takes place, this results in modification of DVHs and radiobiological parameters, hence the plan quality. The observed average displacement of needles (1 mm) and of prostate (0.57 mm) is quite small as compared with the average displacement noted in several other reports [A. A. Martinez et al., Int. J. Radiat. Oncol., Biol., Phys. 49(1), 61-69 (2001); S. J. Damore et al., Int. J. Radiat. Oncol., Biol., Phys. 46(5), 1205-1211 (2000); P. J. Hoskin et al., Radiotherm. Oncol. 68(3), 285-288 (2003); E. Mullokandov et al., Int. J. Radiat. Oncol., Biol., Phys. 58(4), 1063-1071 (2004)] in the literature. CONCLUSIONS: Although the decrease of quality of dosimetric and radiobiological parameters occurs, this does not cause clinically unacceptable changes to the 3D dose distribution, according to our clinical protocol.


Asunto(s)
Braquiterapia/métodos , Imagenología Tridimensional/métodos , Movimiento , Neoplasias de la Próstata/diagnóstico por imagen , Neoplasias de la Próstata/radioterapia , Radioterapia Asistida por Computador/métodos , Humanos , Masculino , Próstata/diagnóstico por imagen , Próstata/patología , Próstata/fisiopatología , Próstata/efectos de la radiación , Neoplasias de la Próstata/patología , Neoplasias de la Próstata/fisiopatología , Control de Calidad , Dosificación Radioterapéutica , Ultrasonografía
13.
J Contemp Brachytherapy ; 3(4): 209-19, 2011 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-23346130

RESUMEN

PURPOSE: This study investigates the distortion of geometry of catheters and anatomy in acquired U/S images, caused by utilizing various stand-off materials for covering a transrectal bi-planar ultrasound probe in HDR and LDR prostate brachytherapy, biopsy and other interventional procedures. Furthermore, an evaluation of currently established water-bath based quality assurance (QA) procedures is presented. MATERIAL AND METHODS: Image acquisitions of an ultrasound QA setup were carried out at 5 MHz and 7 MHz. The U/S probe was covered by EA 4015 Silicone Standoff kit, or UA0059 Endocavity balloon filled either with water or one of the following: 40 ml of Endosgel(®), Instillagel(®), Ultraschall gel or Space OAR™ gel. The differences between images were recorded. Consequently, the dosimetric impact of the observed image distortion was investigated, using a tissue equivalent ultrasound prostate phantom - Model number 053 (CIRS Inc., Norfolk, VA, USA). RESULTS: By using the EA 4015 Silicone Standoff kit in normal water with sound speed of 1525 m/s, a 3 mm needle shift was observed. The expansion of objects appeared in radial direction. The shift deforms also the PTV (prostate in our case) and other organs at risk (OARs) in the same way leading to overestimation of volume and underestimation of the dose. On the other hand, Instillagel(®) and Space OAR™ "shrinks" objects in an ultrasound image for 0.65 mm and 0.40 mm, respectively. CONCLUSIONS: The use of EA 4015 Silicone Standoff kit for image acquisition, leads to erroneous contouring of PTV and OARs and reconstruction and placement of catheters, which results to incorrect dose calculation during prostate brachytherapy. Moreover, the reliability of QA procedures lies mostly in the right temperature of the water used for accurate simulation of real conditions of transrectal ultrasound imaging.

14.
J Contemp Brachytherapy ; 2(3): 117-128, 2010 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-27853473

RESUMEN

PURPOSE: One of the issues that a planner is often facing in HDR brachytherapy is the selective existence of high dose volumes around some few dominating dwell positions. If there is no information available about its necessity (e.g. location of a GTV), then it is reasonable to investigate whether this can be avoided. This effect can be eliminated by limiting the free modulation of the dwell times. HIPO, an inverse treatment plan optimization algorithm, offers this option. In treatment plan optimization there are various methods that try to regularize the variation of dose non-uniformity using purely dosimetric measures. However, although these methods can help in finding a good dose distribution they do not provide any information regarding the expected treatment outcome as described by radiobiology based indices. MATERIAL AND METHODS: The quality of 12 clinical HDR brachytherapy implants for prostate utilizing HIPO and modulation restriction (MR) has been compared to alternative plans with HIPO and free modulation (without MR). All common dose-volume indices for the prostate and the organs at risk have been considered together with radiobiological measures. The clinical effectiveness of the different dose distributions was investigated by calculating the response probabilities of the tumors and organs-at-risk (OARs) involved in these prostate cancer cases. The radiobiological models used are the Poisson and the relative seriality models. Furthermore, the complication-free tumor control probability, P+ and the biologically effective uniform dose ([Formula: see text]) were used for treatment plan evaluation and comparison. RESULTS: Our results demonstrate that HIPO with a modulation restriction value of 0.1-0.2 delivers high quality plans which are practically equivalent to those achieved with free modulation regarding the clinically used dosimetric indices. In the comparison, many of the dosimetric and radiobiological indices showed significantly different results. The modulation restricted clinical plans demonstrated a lower total dwell time by a mean of 1.4% that was proved to be statistically significant (p = 0.002). The HIPO with MR treatment plans produced a higher P+ by 0.5%, which stemmed from a better sparing of the OARs by 1.0%. CONCLUSIONS: Both the dosimetric and radiobiological comparison shows that the modulation restricted optimization gives on average similar results with the optimization without modulation restriction in the examined clinical cases. Concluding, based on our results, it appears that the applied dwell time regularization technique is expected to introduce a minor improvement in the effectiveness of the optimized HDR dose distributions.

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