RESUMEN
The primary concerns in the development of a laser catheter for intravascular use are the potential hazards of vessel wall perforation and distal embolization. We present evidence, using technetium 99-labeled thrombi in two rabbit aortas and one human cadaver coronary artery, that distal embolization does not occur after argon laser recanalization. Also, no vessel wall perforation was observed during recanalization of 15 thrombosed rabbit aortas and 1 inferior vena cava, used because of their extremely thin walls. Laser recanalization of three peripheral arteries with atherosclerotic plaque obstruction, in amputated human legs, showed no evidence of vessel wall perforation. The incidence of vessel wall perforation can be minimized by preferential use of the argon laser, strict maintainance of a coaxial relationship between the laser catheter and the vessel, and exercising care during the actual lasing process. Distal embolization does not appear to be an important consideration.
Asunto(s)
Vasos Sanguíneos/lesiones , Embolia/etiología , Terapia por Láser , Trombosis/cirugía , Animales , Enfermedades de la Aorta/cirugía , Enfermedad Coronaria/cirugía , Humanos , Técnicas In Vitro , Rayos Láser/efectos adversos , ConejosRESUMEN
The treatment of operable breast cancer in eighty-two patients older than seventy years was analyzed. The cancers were treated at an advanced stage and the axilla was involved as frequently as in younger women. The factors influencing survival differ because of competing mortalities from heart disease and stroke. The risks are discussed in relation to life expectancy and treatment method.
Asunto(s)
Anciano , Neoplasias de la Mama/cirugía , Carcinoma Intraductal no Infiltrante/cirugía , Adenocarcinoma/cirugía , Factores de Edad , Axila/cirugía , Neoplasias de la Mama/mortalidad , Femenino , Humanos , Esperanza de Vida , Metástasis Linfática , Metástasis de la NeoplasiaRESUMEN
Primary carcinoma of breast was treated in 967 patients from 1962 through 1972. Thirty-five of these patients had a second primary tumor of which 50% were discovered simultaneously. A family history for cancer was recorded in 26% of the patients with bilateral cancer. Patients found their tumor more often than the physician except in the simultaneous cases where the physician was more successful. Pathological examination showed 10% of the tumors were comedo, lobular carcinoma in situ, papillary, or tubular cancers. In the metachronous group, 50% of the axillae were involved on both sides. In the simultaneous cases the axilla was less frequently involved. Mammography, biopsies of the second breast, and prophylactic mastectomy in certain high-risk patients should improve survival rates.