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1.
Ann Hum Genet ; 78(5): 367-80, 2014 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-24962720

RESUMEN

This palaeogenetic study focused on the analysis of a late prehispanic Argentinean group from the Humahuaca valley, with the main aim of reconstructing its (micro)evolutionary history. The Humahuaca valley, a natural passageway from the eastern plains to the highlands, was the living environment of Andean societies whose cultural but especially biological diversity is still poorly understood. We analyzed the DNA extracted from 39 individuals who populated this upper valley during the Regional Development period (RDP) (between the 11th and 15th centuries CE), to determine their maternal and paternal genetic ancestry. Some mitochondrial and Y-chromosomal haplotypes specific to the Andean region are consistent with an origin in the highlands of Central Andes. On the other hand, a significant genetic affinity with contemporary admixed communities of the Chaco area was detected. Expectedly, recent demographic events, such as the expansion of the Inca Empire or the European colonization, have changed the original mitochondrial gene pool of the ancient Humahuaca Valley community. Finally, we identified a particular geographical organization of the prehispanic populations of Northwestern Argentina. Our results suggest that the communities of the region were divided between two different spheres of interaction, which is consistent with assumptions made by means of craniometric traits.


Asunto(s)
Evolución Biológica , Cromosomas Humanos Y/genética , ADN Mitocondrial/genética , Fósiles , Variación Genética , Indígenas Sudamericanos/genética , Arqueología/métodos , Argentina , Secuencia de Bases , Genética de Población , Haplotipos/genética , Historia Medieval , Humanos , Datos de Secuencia Molecular , Análisis de Secuencia de ADN
2.
Am J Phys Anthropol ; 141(3): 452-62, 2010 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-19918991

RESUMEN

Ancient DNA recovered from 21 individuals excavated from burial sites in the Pampa Grande (PG) region (Salta province) of North-Western Argentina (NWA) was analyzed using various genetic markers (mitochondrial DNA, autosomal STRs, and Y chromosomal STRs). The results were compared to ancient and modern DNA from various populations in the Andean and North Argentinean regions, with the aim of establishing their relationships with PG. The mitochondrial haplogroup frequencies described (11% A, 47% B, and 42% D) presented values comparable to those found for the ancient Andean populations from Peru and San Pedro de Atacama. On the other hand, mitochondrial and Y chromosomal haplotypes were specific to PG, as they did not match any other of the South American populations studied. The described genetic diversity indicates homogeneity in the genetic structure of the ancient Andean populations, which was probably facilitated by the intense exchange network in the Andean zone, in particular among Tiwanaku, San Pedro de Atacama, and NWA. The discovery of haplotypes unique to PG could be due to a loss of genetic diversity caused by recent events affecting the autochthonous populations (establishment of the Inca Empire in the region, colonization by the Europeans).


Asunto(s)
Cromosomas Humanos Y/genética , ADN/genética , Paleontología/métodos , Argentina , Entierro/métodos , ADN/aislamiento & purificación , ADN Mitocondrial/genética , Perfilación de la Expresión Génica/métodos , Marcadores Genéticos , Variación Genética , Genética Médica/métodos , Humanos , Masculino , Repeticiones de Microsatélite/genética , Museos , Reacción en Cadena de la Polimerasa/métodos , América del Sur
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