Retrograde root canal retreatment with pre-bent ultrasonic files. A retrospective outcome study.

AIM: To assess retrospectively the clinical and radiographic outcomes of retrograde root canal retreatment (RRR) and to identify possible prognostic factors that may affect the outcome. METHODOLOGY: Clinical records and radiographs were collected from patients who had undergone RRR between 2009 and 2016 and had a 1-year follow-up. All surgical procedures were performed by a single endodontist. The RRR technique involved minimal root-end resection and maximal length retrograde preparation using pre-bent ultrasonic files. Outcomes were categorized as complete, incomplete, uncertain or unsatisfactory healing based on clinical and radiographic findings. The complete and incomplete healing cases were pooled and considered as successes, while uncertain and unsatisfactory cases were considered failures. Prognostic factors were analysed using univariate analysis and multivariate logistic regression. RESULTS: In total, 575 patients with 721 teeth were included. The overall success rate was 91.8%. None of the prognostic factors (including age, gender, size of periapical radiolucency and isthmus presence) had a significant influence on the outcome (P > 0.05). Univariate analysis revealed tooth type had a significant influence on outcome (P = 0.008) with mandibular incisors having a significantly lower success rate (71.4%). Multivariate analysis using logistic regression revealed that the only variable with a significant association to the outcome was retrograde preparation length (P = 0.016, odds ratio = 1.299 (1.050, 1.607), C.I. = 95%)), i.e. the longer the retrograde preparation, the better the outcome. CONCLUSIONS: Retrograde root canal retreatment was successful in 91.8% of cases. This predictable success rate was achieved while minimizing root-end resection and maximizing retrograde canal preparation length.

Incidence of microcracks in maxillary first premolars after instrumentation with three different mechanized file systems: a comparative ex vivo study.

OBJECTIVES: The objective of this study is to determine the potential for microcracks in the radicular dentin of first maxillary premolars using three different mechanized endodontic instrumentation systems. METHODS: Eighty extracted maxillary first premolars with two root canals and no externally visible microcracks were selected. Root canal instrumentation was performed with either the ProTaper file system, the WaveOne primary file, or the self-adjusting file (SAF). Teeth with intact roots served as controls. The roots were cut into segments and examined with an intensive, small-diameter light source that was applied diagonally to the entire periphery of the root slice under ×20 magnification; the presence of microcracks and fractures was recorded. Pearson's chi-square method was used for statistical analysis, and significance was set at p < 0.05. RESULTS: Microcracks were present in 30 and 20 % of roots treated with the ProTaper and WaveOne systems, respectively, while no microcracks were present in the roots treated with the SAF (p = 0.008 and p = 0.035, respectively). Intact teeth presented with cracks in 5 % of the roots. The intensive, small-diameter light source revealed microcracks that could not be detected when using the microscope's light alone. CONCLUSIONS: Within the limitations of this study, it could be concluded that mechanized root canal instrumentation with the ProTaper and WaveOne systems in maxillary first premolars causes microcracks in the radicular dentin, while the use of the SAF file causes no such microcracks. CLINICAL RELEVANCE: Rotary and reciprocating files with large tapers may cause microcracks in the radicular dentin of maxillary first premolars. Less aggressive methods should be considered for these teeth.

Does root canal treatment in necrotic pulp or retreatment cases with periapical lesions require anaesthesia? An in vivo clinical study.

AIM: To examine whether local anaesthesia is required for treating teeth with necrotic pulps (TNP) and retreatment cases (RCs) associated with periapical lesions. METHODOLOGY: Root canal treatment was performed in TNP and RCs without the administration of local anaesthesia. Patients were assured that if they experienced pain, local anaesthesia would be provided. Eighty canals, 40 TNP and 40 RCs, were included in the study. Two length measurements were performed: one using an electronic apex locator (EAL), which was defined as the electronic length (EL), and the second, the length at which the patient first reported that a size 15 file was touching the periapical tissues, which was defined as the periodontal length (PL). The difference between these two measurements (Δ = PL - EL) was the parameter studied. Statistical analysis was conducted using two-way anova and paired t-tests. Working length (WL) was defined in this study as being 0.5 mm short of the EL. RESULTS: EL was shorter than PL in 96% of cases. The mean difference between measurements was 0.78 (±0.11) mm in the TNP group and 0.63 (±0.15) mm in the RC group; the difference was not significant. The distances between the WL and PL were thus 1.28 and 1.13 mm, respectively. In none of the 80 canals did the patient experience any pain, either during the measurements or during the instrumentation procedures. CONCLUSIONS: When EALs are used, local anaesthesia may not be required for root canal treatment in teeth with necrotic pulps and retreatment cases associated with periapical lesions.

Efficacy of XP-endo finisher files in the removal of calcium hydroxide paste from artificial standardized grooves in the apical third of oval root canals.

AIM: To compare the efficacy of the XP-endo finisher file (XP) (FKG Dentaire, La Chaux de Fonds, Switzerland) to that of passive ultrasonic irrigation (PUI) and conventional syringe and needle irrigation (SNI) in the removal of calcium hydroxide paste from an artificial standardized groove in the apical third of root canals. METHODOLOGY: The root canals of 68 mandibular incisors with single oval canals were prepared using Mtwo instruments (VDW GmbH, Munich, Germany) up to size 40, .04 taper. Each tooth was split longitudinally, and in one half of the root, a standardized groove was prepared in the apical part of the specimen. The grooves were filled with Ca(OH)2 , and the root halves were reassembled. The roots were randomly divided into two control groups (n = 4) and three experimental groups (n = 20) according to the Ca(OH)2 methods used: XP, PUI and SNI. The amount of remaining medicament was evaluated under X25 magnification using a 4-grade scoring system. Kappa values were calculated for intra- and interobserver agreement evaluation. The differences in the Ca(OH)2 scores amongst the different groups were analysed using the Kruskal-Wallis test. RESULTS: None of the tested methods could completely clean the Ca(OH)2 from the artificial standardized groove in the apical third of the root canals. XP and PUI removed significantly more Ca(OH)2 than SNI (P < 0.001), with no significant differences between them (P = 0.238). CONCLUSIONS: XP and PUI were more effective in removing Ca(OH)2 from artificial standardized grooves in the apical third of root canals than SNI.

Can size 20, .04 taper rotary files reproducibly create a glide path for the self-adjusting file? An ex vivo study in MB canals of mandibular molars.

AIM: To test and compare the effectiveness and safety of two size 20, .04 taper rotary files that were used to create a glide path for the self-adjusting file (SAF) in curved canals of mandibular molars. METHODOLOGY: Forty mandibular molars with curved mesial roots and narrow MB root canals were selected based on a passage of size 15 K-files to WL; size 20 K-files could not reach WL. Only roots with no visible microcracks were included. Two types of size 20 rotary files were used for glide path preparation, the new Pre-SAF size 20, .04 taper file and the ProFile size 20, .04 taper, which served as the reference and control. Both files were used with 3-4 pecking strokes, which brought them to WL. Two parameters were tested whether the glide path allowed manual insertion of a 1.5-mm SAF file to WL and whether the procedure caused microcracks in the root dentine. Paired t-tests were used to compare the groups. RESULTS: Glide path preparation with both files allowed the manual insertion of the SAF file to WL in all 20 root canals, with no difference between the two groups. No cracks were detected after the procedure in any of the roots in either group. CONCLUSIONS: Both types of size 20, .04 taper rotary files were effective for glide path preparation for the SAF file in curved canals. Neither file type caused microcracks in root dentine.

Push-out bond strength of root fillings made with C-Point and BC sealer versus gutta-percha and AH Plus after the instrumentation of oval canals with the Self-Adjusting File versus WaveOne.

AIM: To compare the push-out bond strength exhibited by root fillings performed with either C-Point and Endosequence® BC sealer™ (BC Sealer) or gutta-percha and AH Plus® after the instrumentation of oval canals with either the Self-Adjusting File (SAF) System or WaveOne (WO) reciprocating file. METHODOLOGY: Eighty extracted premolars were selected and divided randomly into the following four groups (n = 20): group 1, SAF instrumentation and filling using gutta-percha and AH Plus sealer; group 2, SAF instrumentation and C-Point and BC sealer filling; group 3, WO instrumentation and filling using gutta-percha and AH Plus sealer; and group 4, WO instrumentation and filling with C-Point and BC sealer. Sodium hypochlorite (5.25%) and EDTA (17%) were used as irrigants for all groups. After the sealer was set completely, the teeth were prepared for micro push-out assessment using 1.0-mm-thick root slices. Loading was performed with a universal testing machine at a speed of 0.5 mm min(-1) . Two-way anova and Student's t-test for pairwise comparisons were used to compare groups. RESULTS: All specimens filled with C-Point and BC sealer were associated with significantly higher push-out bond strength compared with gutta-percha and AH Plus sealer (P < 0.001). The bond strength was higher for the coronal and apical samples of the C-Point/BC sealer/SAF group (6.6 ± 0.3 and 3.2 ± 0.3 MPa) versus those of the gutta-percha/AH Plus/WO group (4.8 ± 0.3 and 1.8 ± 0.3 MPa), by 38% and by 80% in the coronal and apical parts, respectively (P < 0.001, P < 0.0001). Adhesive bond failure was more common in the WaveOne-instrumented group in general and in the buccal and lingual recesses in this group in particular. CONCLUSIONS: In oval canals, the instrument used and the root filling material significantly affected the push-out values of root fillings. The highest value was recorded in oval root canals instrumented with the SAF System and filled with C-Point and BC sealer, whereas the lowest strength was noted in oval canals instrumented with WaveOne and filled with gutta-percha and AH Plus sealer.

The diagnosis and conservative treatment of a complex type 3 dens invaginatus using cone beam computed tomography (CBCT) and 3D plastic models.

AIM: To investigate the use of 3D plastic models, printed from cone beam computed tomography (CBCT) data, for accurate diagnosis and conservative treatment of a complex case of dens invaginatus. SUMMARY: A chronic apical abscess with a draining sinus tract was diagnosed during the treatment planning stage of orthodontic therapy. Radiographic examination revealed a large radiolucent area associated with an invaginated right maxillary central incisor, which was found to contain a vital pulp. The affected tooth was strategic in the dental arch. Conventional periapical radiographs provided only partial information about the invagination and its relationship with the main root canal and with the periapical tissues. A limited-volume CBCT scan of the maxilla did not show evidence of communication between the infected invagination and the pulp in the main root canal, which could explain the pulp vitality. A novel method was adopted to allow for instrumentation, disinfection and filling of the invagination, without compromising the vitality of the pulp in the complex root canal system. The CBCT data were used to produce precise 3D plastic models of the tooth. These models facilitated the treatment planning process and the trial of treatment approaches. This approach allowed the vitality of the pulp to be maintained in the complex root canal space of the main root canal whilst enabling the healing of the periapical tissues. KEY LEARNING POINTS: Even when extensive periapical pathosis is associated with a tooth with type III dens invaginatus, pulp sensibility tests should be performed. CBCT is a diagnostic tool that may allow for the management of such teeth with complex anatomy. 3D printed plastic models may be a valuable aid in the process of assessing and planning effective treatment modalities and practicing them ex vivo before actually performing the clinical procedure. Unconventional technological approaches may be required for detailed treatment planning of complex cases of dens invaginatus.

Incorporation of chlorhexidine diacetate in provisional cements: antimicrobial activity against Streptococcus mutans and the effect on tensile strength in vitro.

AIM: To test the antibacterial capacities and tensile strengths of three commercially available provisional cements to which chlorhexidine diacetate was added and compare them to the same unmodified cements. METHODOLOGY: Sixty cylindrical samples were prepared from either three noneugenol provisional cements or the same cements modified by the addition of chlorhexidine diacetate at 7.5% w/w, with a total of 360 samples. The cements tested included Tempbond NE, Rely X Temp NE and Freegenol. Forty-eight samples from each cement were aged in saline that was replaced twice a week for up to 96 days. Twelve of these samples were removed at either 1, 15, 30 or 96 days and assessed for antibacterial properties against Streptococcus mutans with an agar diffusion test. Twelve samples of each cement, with and without chlorhexidine diacetate, were also tested 7 days after the initial setting for their tensile strength using a diametrical tensile strength test applied with an Instron machine. The results were analysed using either one-way or three-way anova. RESULTS: The addition of chlorhexidine diacetate resulted in provisional cements with antibacterial properties that persisted through ageing in saline for up to 96 days. The addition of chlorhexidine did not reduce the diametrical strength of the cements. CONCLUSIONS: The addition of chlorhexidine diacetate to provisional cements rendered all three cements antibacterial against S. mutans and this activity was maintained even after prolonged ageing of the cements, without compromising their tensile strength at 7 days.

The effectiveness of a self-adjusting file to remove residual gutta-percha after retreatment with rotary files.

AIM: To test the efficacy of a two-stage retreatment method in which the Self-Adjusting File (SAF) is used to remove root canal filling residue left in the canal after using ProTaper Universal retreatment files. METHOD: One of the curved mesial canals of 25 extracted mandibular molars was instrumented up to ProTaper F2, followed by NiTi K-files up to size 45 and filled. Radiographs of these canals served as a pre-treatment control, which was later compared with those of the same canals after each stage of the retreatment procedure. Stage 1 consisted of ProTaper Universal D1-D3 retreatment files, which were used to remove the bulk of root filling material, followed by stage 2 in which a SAF file was applied to remove the remaining root canal filling residue. The amount of the radiopaque material in each third of the canal was evaluated before and after each stage, using bucco-lingual and mesio-distal radiographs. The amount of residue was expressed as the per cent of the root canal filled area, as measured in the pre-treatment control. The difference between the control and results of the first and second stages of retreatment was analysed using the Wilcoxon signed-rank test. RESULTS: Radiopaque residue was present after the use of the ProTaper Universal rotary files in 7.8 (± 12.9)%, 12.9 (± 13.9)% and 34.7 (± 22.8)% of the coronal, mid-root and apical areas, respectively. Following the supplementary application of the SAF, the amounts of residue were reduced to 2.6 (± 3.7)%, 4.1 (± 5.7)% and 6.7 (± 9.4)% of the coronal, mid-root and apical canal areas, respectively (P < 0.01 for the coronal and mid-root and P < 0.001 for the apical third). CONCLUSION: No system removed the root filling materials entirely. The use of the SAF after rotary instrumentation using ProTaper Universal retreatment files resulted in a significant reduction in the amount of filling residue in curved canals of mandibular molars.

The efficacy of five techniques for removing root filling material: microscopic versus radiographic evaluation.

AIM: To test and compare the efficacy of five methods for the removal of root filling material and to test the hypothesis that radiographs fail to represent the real extent of remaining material on canal walls. METHODOLOGY: Fifty maxillary anterior single-rooted teeth with straight root canals were selected. The coronal third of each root canal was prepared with Gates-Glidden drills to number 3, whilst the apical two-thirds were prepared with manual K-files to size 40. Root fillings were performed using lateral compaction with gutta-percha and AH-26. After full setting, the coronal third of the root filling was removed with Gates-Glidden drills and the teeth divided into five groups (n=10). The remaining root filling material was then removed with either Hedström files and chloroform (25 µL), using size 40 as the last file, SafeSider files, using a NiTi Pleezer reamer with a 0.06 taper followed by size 40 reciprocating file, with or without chloroform, or ProTaper Universal retreatment files (D2, D3) with or without chloroform. Reaching working length with no more gutta-percha on the last file was defined as the endpoint for all procedures. The presence of remaining filling material was first evaluated radiographically and then by the microscopic evaluation of split roots. The time required to accomplish the procedure was also recorded. anova and anova with repeated measures were used for statistical analysis of the results. RESULTS: Overall, 11-26% of the canal wall remained covered with filling material; no significant difference was found between the groups. The mechanized methods were faster than manual removal of filling material (P < 0.01); the use of solvent did not speed up the mechanized procedures. Radiographic evaluation failed to adequately and reliably detect the extent of filling material remaining on the canal walls, which was later observed by microscopic evaluation. CONCLUSIONS: All methods left root canal filling material on the canal walls. Radiographic evaluation failed to detect the extent of remaining root filling material, which could only be detected using microscopy.

Hard-tissue debris accumulation created by conventional rotary versus self-adjusting file instrumentation in mesial root canal systems of mandibular molars.

AIM: To evaluate the accumulation of hard-tissue debris when using the Self-adjusting File (SAF) system in mesial roots of mandibular molars with isthmuses and to compare it with that occurring when the ProTaper file system was used. METHODOLOGY: Forty extracted human mandibular molars with joining mesial root canals and an isthmus between the two canals were randomly assigned to two experimental groups and scanned using micro-computed tomography. Root canals in the control group (N = 20) were instrumented using the ProTaper rotary system until F3. Irrigation with 1 mL of 3% NaOCl solution was applied after each instrument. Root canals in the experimental group (N = 20) were prepared using the SAF for 4 min, with continuous irrigation (3% NaOCl, 4 mL min(-1)). After rescanning, canals in both groups were further irrigated with 5 mL of 17% EDTA for 2 min. After final scanning, the per cent value of total canal system volume filled with hard-tissue debris was calculated. Statistical analysis was performed using Mann-Whitney U-test; the alpha-type error was set at 1%. RESULTS: Instrumentation of the root canals with ProTaper left 10.1% (IQR 5.2) of the total canal system volume filled with hard-tissue debris while preparation with the SAF left 1.7% (IQR 1.6). This difference was highly significant (P < 0.0001). After subsequent EDTA irrigation, these values were significantly reduced (P < 0.01) to 7.9% (IQR 4.1) and 1.3% (IQR 0.8) in the ProTaper and SAF groups, respectively. CONCLUSION: Preparation with the SAF system resulted in less hard-tissue debris accumulation in isthmus-containing root canal systems compared with instrumentation with ProTaper rotary files.

The effect of maintaining apical patency on canal transportation.

AIM: To evaluate, ex vivo, the effect of maintaining apical patency on the original canal shape during preparation of curved roots by two different techniques. METHODOLOGY: Forty extracted human maxillary and mandibular molars were evaluated. Occlusal surfaces were ground and roots sectioned to the level of the cemento-enamel junction to allow only one root to remain for evaluation in each tooth. Specimens were divided into four experimental groups (10 canals each): Group 1--root canals prepared using the balanced force technique with stainless steel K-files, and patency established with size 10 K-files between each instrument; Group 2--same as Group 1 but without the use of a patency file; Group 3--canals instrumented with LightSpeed instruments and patency established with size 10 K-files between each instrument; and Group 4--same as Group 3 but without the use of a patency file. Specimens were mounted and a series of radiographs taken. Initial and post-preparation digital images were superimposed and the distance between two central axes at 1, 2 and 4 mm from the working length (WL) was measured to obtain an indication of the degree of apical transportation. Results were subjected to statistical analysis using two-way analysis of variance (ANOVA). RESULTS: No significant differences were found in degree of apical transportation at different levels of the root canal (P > 0.05) nor in loss of WL between groups (P > 0.05). CONCLUSION: In this laboratory study, maintaining apical patency did not influence canal transportation in the apical 4 mm.

Low-dose doxycycline inhibits bone resorption associated with apical periodontitis.

AIM: To test the effect of low-dose doxycycline on bone resorption associated with apical periodontitis. METHODOLOGY: Apical periodontitis was induced by occlusal pulp exposure in the mandibular first molars of 36 rats. Animals were divided into three groups of 12: group A received doxycycline in drinking water at a dose of 5.85 mg day(-1); group B received a dose of 1.48 mg day(-1) (one-quarter of the original dose); and group C received no medicament and served as the control. A bioassay determined the doxycycline serum levels. After 21 days, the mandibles were removed, radiographed and the radiographs scanned to generate digital images. These images were analysed morphometrically and the total area of the periapical bone resorption of the mesial and distal roots of each tooth was determined and used to compare the groups. Statistical analysis was completed using anova with repeated measures. RESULTS: The mean doxycycline serum level in group A was 0.22(+/-0.03) microg mL(-1) and in group B below the detection level of the assay (<0.062 microg mL(-1)). The mean area of the periapical bone resorption in the control group C was 2.91(+/-0.61) mm(2). In animals treated with a low-dose doxycycline, the mean size of the bone resorption was significantly smaller at 1.59(+/-0.59) mm(2) (group A) and 1.72(+/-0.85) mm(2) (group B) (P = 0.001). No significant difference was found in the area of the bone resorption between these two groups A and B. CONCLUSIONS: Low-dose doxycycline reduced the area of bone resorption associated with apical periodontitis in the mandibular first molar teeth of rats.

[Vertical root fractures in endodontically treated teeth--Part II: Etiology and prevention].

The etiologic factors for vertical fractures in endodontically treated teeth are predisposing factors, such as loss of tooth material, anatomy of the susceptible teeth, moisture loss, previous dentinal cracks, and loss of bone support; and iatrogenic factors, such as excessive removal of radicular dentin as a result of endodontic and prosthetic procedures and improper selection of dowels. Identification of susceptible teeth and roots, proper selection and cementation of dowels, and avoidance of excessive force during condensation of gutta percha and in removal of tooth structure during endodontic and prosthetic procedures, are all measures that can be taken to prevent root fractures.

Comparison of procedural errors resulting during root canal preparations completed by junior dental students in patients using an '8-step method' versus 'serial step-back technique.'.

AIM: To compare procedural errors occurring during preparation of root canals by junior dental students in patients using a new '8-step method' versus traditional 'serial step-back technique. METHODOLOGY: Junior dental students treated 291 root canals of maxillary and mandibular teeth in patients. A new '8-step method' was used to prepare 149 canals, whilst the traditional 'serial step-back technique' was used for 142 root canals. Instrumentation was carried out in both techniques using standardized stainless steel K-files and coronal flaring with Gates-Glidden reamers. In the apical one-third, a filing motion was used in the traditional technique: with the '8-step method,' reaming or filing motions were used in sizes up to 25 and only reaming in sizes larger than 25. All root canals were obturated with gutta-percha points and AH26 using a lateral condensation technique. Pre- and postoperative radiographs were made of each tooth. Procedural errors were recorded and statistically analysed using a binomic test for comparison of proportion. RESULTS: Significantly (P < (1.0001) more root canals maintained their original shape with no deviation (91%) with the'8-step method' compared to the traditional 'serial step-back technique' (61%). The procedural errors detected with the'8-step method' consisted of 10 canals with transportation (5%) and five with root perforations (2%); there were no canal obstructions. With the 'serial step-back technique: significantly (P < 0.0001) more errors occurred: 28 canals were transported (17%), 10 had root perforations (7%), and 16 canals were obstructed (6%). The differences in maintaining the original root canal shape between the two methods were significantly greater in molar versus anterior teeth. CONCLUSIONS: The new '8-step method' resulted in fewer procedural errors than the traditional 'serial step-back technique' when junior students prepared root canals in patients.

Jewish emigration from Israel.

PIP: Issues raised by the emigration of Jews from Israel are discussed. The primary focus is on the debate within Israel concerning what measures could be taken to reduce emigration levels or to induce emigrants to return to Israel.^ieng