RESUMEN
Left bundle branch area pacing (LBBAP) is an emerging technique in cardiac resynchronization therapy that shows promise in improving ventricular synchrony and clinical outcomes in patients with heart failure. However, the potential risk of coronary artery complications with LBBAP necessitates careful attention and management. This literature review explores the mechanisms, acute coronary events, and clinical implications associated with coronary artery complications in LBBAP. The mechanism of coronary injury with LBBAP involves mechanical trauma, altered coronary blood flow dynamics, and endothelial damage. Acute coronary events such as myocardial ischemia, acute coronary syndromes, and coronary artery dissection can occur during or after LBBAP, leading to significant clinical implications including the need for prompt intervention and potential impact on long-term outcomes. To avoid coronary injury and acute coronary syndrome with LBBAP, specific care strategies are recommended. These include thorough pre-procedural evaluation, expert operator technique, optimization of hemodynamics and ventricular synchrony, close monitoring for ischemic events, collaboration with cardiology specialists, and long-term follow-up. The clinical implications of coronary artery complications with LBBAP necessitate careful patient selection, informed decision-making, and a multidisciplinary approach. Future directions in this field include advancements in procedural techniques, technological innovations, risk stratification strategies, enhanced imaging modalities, research on mechanisms and prevention, and collaboration among stakeholders. By implementing these strategies and focusing on future advancements, healthcare providers can minimize the risk of coronary artery complications with LBBAP and optimize patient outcomes in cardiac resynchronization therapy.
RESUMEN
BACKGROUND: Secundum atrial septal defect is a common congenital heart disease. Amplatzer septal occluder has become the most commonly used device for its closure. This study was conducted to determine the safety and outcome of atrial septal defect closure with the Amplatzer septal occlude (ASO). METHODS: This Case-series was conducted at Armed Forces Institute of Cardiology/National Institute of Heart Diseases Rawalpindi from July 2010-11, on a total of 41 patients, out of these 41 patients, 18 (44%) patients underwent general anaesthesia while 23 (56%) patients were given local anaesthesia for the procedure. Trans-esophageal echocardiogram was done in all patients before procedure. RESULTS: In 37 patients, ASD device closure was successfully done and size of ASD devices were 14-36 mm. Trans-oesophageal echocardiography guided ASD Device closure was done in 16 patients and rest of them done under transthoracic echocardiography. Size of ASD ranged from 11-36 mm (mean 22 mm). Mean floro time was 10 minutes. Four (10%) patients did not undergo the procedure due to inadequate rim. CONCLUSION: Device closure of Atrial Septal Defect with amplatzer septal occluder is convenient and safe.