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1.
J Orthop Sci ; 2023 Dec 07.
Artículo en Inglés | MEDLINE | ID: mdl-38065792

RESUMEN

BACKGROUND: Previous studies have demonstrated that the point prevalence of back pain ranges from 12 % to 33 % and that the lifetime prevalence of back pain ranges from 28 % to 51 % in adolescents. However, few studies on back pain in patients with Adolescent idiopathic scoliosis (AIS) have been conducted, and these studies had significant limitations, including a lack of comparative controls and detailed information about scoliotic deformity or pain location. This study aimed to determine whether adolescents with AIS experience back pain in specific regions. METHODS: This retrospective case-control study included 189 female adolescents with AIS who underwent corrective fusion from 2008 to 2020. Questionnaires on back pain and health-related quality of life (HRQOL) using the Scoliosis Research Society Outcomes Instrument-22 (SRS-22) were conducted preoperatively. The control group included 2909 general female adolescents. RESULTS: The mean Cobb angles in the main thoracic and thoracolumbar/lumbar curves were 51.4 ± 15.3° and 40.4 ± 12.9°. Back pain characteristics included higher point prevalence (25.9 %) and lifetime prevalence (64.6 %) compared to healthy controls. Adolescents with back pain showed lower scores in the pain and mental health domains of the SRS-22. Adolescents with major thoracic AIS showed more back pain in the upper and middle right back compared to adolescents with major thoracolumbar/lumbar AIS. CONCLUSION: The point and lifetime prevalence of back pain were definitely higher in patients with AIS, which affected their HRQOL. There was a relationship between pain around the right scapula and the right major thoracic curve with a rib hump deformity.

2.
Sci Rep ; 12(1): 8854, 2022 05 25.
Artículo en Inglés | MEDLINE | ID: mdl-35614084

RESUMEN

Teriparatide (TPTD) administration has a potent osteogenic action and promotes the healing of osteoporotic vertebral fractures (OVFs). We aimed to investigate the outcomes of vertebroplasty with posterior spinal fusion (VP + PSF) and determine the impact of perioperative TPTD administration. We included 73 patients (18 male and 55 female patients; mean age: 78 years) with thoracolumbar OVFs who underwent VP + PSF and were followed-up for at least 2 years. Twenty-three patients who received TPTD perioperatively for > 3 months were included in the TPTD group, and the remaining 50 patients were included in the non-TPTD group. Radiographic findings regarding sagittal alignment and clinical outcomes in both groups were compared. The mean duration of TPTD administration was 17.5 ± 5.0 months (range 4-24 months). The mean loss of correction of local kyphosis angle in the TPTD group (4.0°) was lesser than that in the non-TPTD group (7.5°; p < 0.05); however, no significant differences were observed between the groups regarding global sagittal alignment, the occurrence of subsequent vertebral fractures, pedicle screw loosening and treatment-efficacy rates of clinical outcomes. Local kyphosis correction in patients who underwent VP + PSF for OVFs could be maintained through perioperative TPTD administration; however, TPTD administration had little effect on clinical outcomes.


Asunto(s)
Cifosis , Fracturas Osteoporóticas , Fracturas de la Columna Vertebral , Fusión Vertebral , Vertebroplastia , Anciano , Femenino , Humanos , Cifosis/etiología , Vértebras Lumbares/lesiones , Vértebras Lumbares/cirugía , Masculino , Fracturas Osteoporóticas/tratamiento farmacológico , Fracturas Osteoporóticas/etiología , Fracturas Osteoporóticas/cirugía , Estudios Retrospectivos , Fracturas de la Columna Vertebral/tratamiento farmacológico , Fracturas de la Columna Vertebral/cirugía , Fusión Vertebral/efectos adversos , Teriparatido/uso terapéutico , Vértebras Torácicas/lesiones , Vértebras Torácicas/cirugía , Resultado del Tratamiento , Vertebroplastia/efectos adversos
3.
Spine (Phila Pa 1976) ; 45(5): 300-308, 2020 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-31524820

RESUMEN

STUDY DESIGN: Retrospective multi-center study. OBJECTIVE: To identify the morphological features of costovertebral joints and ribs in surgically managed cervical injury patients with diffuse idiopathic skeletal hyperostosis (DISH) and to examine its impact on their vital prognosis. SUMMARY OF BACKGROUND DATA: Several reports have indicated that DISH is an independent risk factor for mortality after spinal fracture. The reason for the high mortality in cervical injury patients with DISH is unclear, although some reports have suggested a possible association between pulmonary complications and mortality. METHODS: From 1999 to 2017, a total of 50 DISH patients (44 males) with cervical spine injuries who underwent spinal surgery were enrolled (average age 74 yrs). Prognosis and clinical risk factor data were collected; the morphological features of the patients' costovertebral joints and ribs were evaluated with computed tomography. The influence of each proposed risk factor and thoracic morphological feature on mortality was tested with univariate and multivariate analyses. RESULTS: The survival rate at 5 years after surgery was 52.3%. Nineteen (38%) patients died, and the most common cause of death was pneumonia (68%). Costovertebral bone excrescences and rib hyperostosis were found to be thoracic pathognomonic signs; their frequencies were 94% and 82%, respectively, and these conditions occurred in an average of 7.0 joints and 4.7 bones, respectively. The results of the log-rank test showed a significant difference in age, injury severity score (ISS), costovertebral bone excrescences, and rib hyperostosis. The results of age-adjusted multivariate analysis indicated that age (hazard ratio [HR] = 8.65, 95% confidence interval [CI] = 1.10-68.28, P = 0.041) and rib hyperostosis (HR = 3.82, 95% CI = 1.38-10.57, P = 0.010) were associated with mortality. CONCLUSION: Reduced chest wall mobility associated with rib hyperostosis in cervical spine injury patients with DISH leads to a poor prognosis. LEVEL OF EVIDENCE: 3.


Asunto(s)
Vértebras Cervicales/diagnóstico por imagen , Vértebras Cervicales/lesiones , Hiperostosis Esquelética Difusa Idiopática/diagnóstico por imagen , Costillas/diagnóstico por imagen , Traumatismos Vertebrales/diagnóstico por imagen , Adulto , Anciano , Anciano de 80 o más Años , Vértebras Cervicales/cirugía , Femenino , Humanos , Hiperostosis Esquelética Difusa Idiopática/complicaciones , Hiperostosis Esquelética Difusa Idiopática/cirugía , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Costillas/cirugía , Factores de Riesgo , Traumatismos Vertebrales/complicaciones , Traumatismos Vertebrales/cirugía , Tomografía Computarizada por Rayos X/efectos adversos
4.
BMC Musculoskelet Disord ; 20(1): 327, 2019 Jul 13.
Artículo en Inglés | MEDLINE | ID: mdl-31299959

RESUMEN

BACKGROUND: This study was conducted to determine gender differences in the relationship between extracurricular sports activities (ECSA) and low back pain (LBP) in children and adolescents. METHODS: In a cohort analysis of a 6-year birth cohort annual survey, students were followed from the fourth to sixth grades of elementary school (E4-E6; 9-12 years old) through the first to third grades of junior high school (J1-J3; 12-15 years old). All students completed annual questionnaires on ECSA and LBP. The odds ratio (OR) and 95% confidence interval (CI) were calculated to assess the association strength between ECSA and LBP. We also calculated the population attributable fraction (PAF), which was defined as the proportion of students with ECSA-related LBP among all students with LBP. RESULTS: ECSA was significantly associated with LBP only in grade J3 among boys (OR: 2.00, 95% CI: 1.47-2.71). On the other hand, among girls, ECSA was significantly associated with LBP in grades E5 (OR: 1.48, 95% CI: 1.00-2.20), E6 (OR: 1.91, 95% CI: 1.33-2.75), and J3 (OR: 1.81, 95% CI: 1.26-2.61). Among boys, PAF was similar in all grades (range, 10-16%), whereas among girls, the PAF varied (- 11 to 29%) and was significantly higher in girls than in boys in grades E5 (19.0% vs. 1.1%, P < 0.01) and E6 (28.8% vs. 12.8%, P < 0.01). CONCLUSIONS: Although there was a link between ECSA and LBP in both boys and girls, girls were more susceptible to ECSA-related LBP, especially in grades E5 and E6.


Asunto(s)
Dolor de la Región Lumbar/epidemiología , Deportes/estadística & datos numéricos , Adolescente , Niño , Femenino , Estudios de Seguimiento , Humanos , Japón/epidemiología , Dolor de la Región Lumbar/etiología , Masculino , Prevalencia , Factores de Riesgo , Factores Sexuales , Estudiantes/estadística & datos numéricos , Encuestas y Cuestionarios/estadística & datos numéricos
5.
Int Orthop ; 40(11): 2309-2315, 2016 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-27194159

RESUMEN

PURPOSE: The study aimed to investigate the clinical outcomes and limitations after vertebroplasty with posterior spinal fusion (VP+PSF) without neural decompression for osteoporotic vertebral collapse. METHODS: We conducted a prospective multicenter study including 45 patients (12 men and 33 women, mean age: 77.0 years) evaluated between 2008 and 2012. Operation time, blood loss, visual analog scale (VAS) of back pain, neurological status, kyphosis angle in the fused area, and vertebral union of the collapsed vertebra were evaluated. RESULTS: The mean operation time was 162 min and blood loss was 381 mL. The postoperative VAS score significantly improved, and the neurological status improved in 35 patients (83 %), and none of the remaining patients demonstrated a deteriorating neurological status at two years post-operatively. The mean kyphosis angle pre-operatively, immediately post-operatively, and two years post-operatively was 23.8°, 10.7°, and 24.3°, respectively, and there was no significant difference between the angles pre-operatively and two years post-operatively. The extensive correction of kyphosis >16° was a risk factor for a higher correction loss and subsequent fracture. Union of the collapsed vertebra was observed in 43 patients (95 %) at two years post-operatively. CONCLUSIONS: The present study suggests that spinal stabilization rather than neural decompression is essential to treat OVC. Short-segment VP+PSF can achieve a high union rate of collapsed vertebra and provide a significant improvement in back pain or neurological status with less invasive surgery, but has a limit of kyphosis correction more than 16°.


Asunto(s)
Fracturas por Compresión/cirugía , Osteoporosis/complicaciones , Fracturas Osteoporóticas/cirugía , Fracturas de la Columna Vertebral/cirugía , Fusión Vertebral , Vertebroplastia , Anciano , Anciano de 80 o más Años , Descompresión Quirúrgica , Femenino , Humanos , Vértebras Lumbares/cirugía , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Vértebras Torácicas/cirugía
6.
J Orthop Sci ; 21(3): 282-6, 2016 May.
Artículo en Inglés | MEDLINE | ID: mdl-27021250

RESUMEN

PURPOSE: To elucidate clinico-radiological features, therapeutic outcomes, and survival factors of vertebral osteomyelitis patients infected by methicillin-resistant staphylococci (MRS). METHODS: Vertebral osteomyelitis patients admitted to the orthopaedic department between 2007 and 2011 (n = 248) were selected for this multicenter study. We compared patients' backgrounds, therapeutic course, and in-hospital mortality between MRS and methicillin-susceptible staphylococci (MSS). We also examined survival factors of vertebral osteomyelitis due to MRS. RESULTS: Sixteen patients of MRS vertebral osteomyelitis and 55 patients of MSS were included in this study. In MRS vertebral osteomyelitis, the rates of comorbid diabetes mellitus, involvement of >2 vertebral bodies, in-hospital mortality, and operation of surgical debridement were higher compared to those in MSS vertebral osteomyelitis. Univariate analysis showed that operation of surgical debridement was a factor related to survival in MRS patients. CONCLUSIONS: Higher rate of comorbid diabetes mellitus, involvement of >2 vertebral bodies, in-hospital mortality, and performing surgical debridement are peculiar features of MRS vertebral osteomyelitis compared to MSS vertebral osteomyelitis. If patients with MRS vertebral osteomyelitis respond poorly to antibiotic therapy, it might be better to consider surgical debridement not to lose an opportunity of operation due to exacerbation of systemic conditions.


Asunto(s)
Staphylococcus aureus Resistente a Meticilina/aislamiento & purificación , Osteomielitis/microbiología , Osteomielitis/mortalidad , Espondilitis/microbiología , Espondilitis/mortalidad , Infecciones Estafilocócicas/mortalidad , Adulto , Anciano , Antibacterianos/uso terapéutico , Causas de Muerte , Bases de Datos Factuales , Desbridamiento/métodos , Femenino , Estudios de Seguimiento , Mortalidad Hospitalaria , Humanos , Japón , Masculino , Staphylococcus aureus Resistente a Meticilina/efectos de los fármacos , Pruebas de Sensibilidad Microbiana , Persona de Mediana Edad , Osteomielitis/diagnóstico , Osteomielitis/terapia , Estudios Retrospectivos , Medición de Riesgo , Índice de Severidad de la Enfermedad , Columna Vertebral/diagnóstico por imagen , Columna Vertebral/microbiología , Espondilitis/diagnóstico por imagen , Espondilitis/terapia , Infecciones Estafilocócicas/diagnóstico por imagen , Infecciones Estafilocócicas/terapia , Estadísticas no Paramétricas , Análisis de Supervivencia
7.
Eur Spine J ; 20(1): 94-9, 2011 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-20582557

RESUMEN

A cross-sectional study that targeted a total of 43,630 pupils in Niigata City, Japan was performed. The objective of the study was to evaluate the association between sports activities and low back pain (LBP) in childhood and adolescence in Japan. Regarding risk factors of LBP, a large number of studies have been conducted that have examined gender differences, height and weight, body mass index, sports time, differences in lifestyle, family history, and mental factors; however, no definitive conclusion has yet been made. A questionnaire survey was conducted using 43,630 pupils, including all elementary school pupils from the fourth to sixth grade (21,893 pupils) and all junior high pupils from the first to third year (21,737 pupils) in Niigata City (population of 785,067). 26,766 pupils who were determined to have valid responses (valid response rate 61.3%) were analyzed. Among the 26,766 pupils with valid responses, 2,591 (9.7%) had LBP at the time of the survey, and 8,588 (32.1%) had a history of LBP. The pupils were divided between those who did not participate in sports activities except the physical education in school (No sports group: 5,486, 20.5%) and those who participated in sports activities (Sports group: 21,280, 79.5%), and the difference in lifetime prevalence between No sports group and Sports group was examined. The odds ratio for LBP according to sports activity was calculated by multiple logistic regression analysis adjusted for gender, age, and body mass index. In addition, the severity of LBP was divided into three levels (Level 1: no limitation in any activity, Level 2: necessary to refrain from participating in sports and physical activities, and Level 3: necessary to be absent from school), and Levels 2 and 3 were defined as severe LBP; the severity was compared between No sports group and Sports group and in each sport's items. Moreover, in Sports group, the amount of time spent participating in sports activities were divided into three groups (Group 1: less than 6 h per week, Group 2: 6-12 h per week, and Group 3: 12.1 h per week or more), and the dose-response between the amount of time spent participating in sports activities and the occurrence of LBP were compared. In No sports group, 21.3% experienced a history of LBP; in Sports group, 34.9% experienced LBP (P < 0.001). In comparison to No sports group, the odds ratio was significantly higher for Sports group (1.57), and also significantly higher for most of the sports items. The severity of LBP was significantly higher in Sports group (20.1 vs. 3.2%, P < 0.001). The amount of time spent participating in sports activities averaged 9.8 h per week, and a history of LBP significantly increased in the group which spent a longer time participating in sports activities (odds ratio 1.43 in Group 3). These findings suggest that sports activity is possible risk factors for the occurrence of LBP, and it might increase the risk for LBP in childhood and adolescence.


Asunto(s)
Estilo de Vida , Dolor de la Región Lumbar/diagnóstico , Dolor de la Región Lumbar/epidemiología , Actividad Motora , Deportes/estadística & datos numéricos , Adolescente , Niño , Estudios Transversales , Femenino , Humanos , Japón/epidemiología , Modelos Logísticos , Masculino , Prevalencia , Factores de Riesgo , Encuestas y Cuestionarios
8.
Eur Spine J ; 20(2): 274-9, 2011 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-21165657

RESUMEN

There have been a few studies regarding detail of back pain in adolescents with idiopathic scoliosis (IS) as prevalence, location, and severity. The condition of back pain in adolescents with IS was clarified based on a cross-sectional study using a questionnaire survey, targeting a total of 43,630 pupils, including all elementary school pupils from the fourth to sixth grade (21,893 pupils) and all junior high pupils from the first to third year (21,737 pupils) in Niigata City (population of 785,067), Japan. 32,134 pupils were determined to have valid responses (valid response rate: 73.7%). In Niigata City, pupils from the fourth grade of elementary school to the third year of junior high school are screened for scoliosis every year. This screening system involves a three-step survey, and the third step of the survey is an imaging and medical examination at the Niigata University Hospital. In this study, the pupils who answered in the questionnaire that they had been advised to visit Niigata University Hospital after the school screening were defined as Scoliosis group (51 pupils; 0.159%) and the others were defined as No scoliosis group (32,083 pupils). The point and lifetime prevalence of back pain, the duration, the recurrence, the severity and the location of back pain were compared between these groups. The severity of back pain was divided into three levels (level 1 no limitation in any activity; level 2 necessary to refrain from participating in sports and physical activities, and level 3 necessary to be absent from school). The point prevalence was 11.4% in No scoliosis group, and 27.5% in Scoliosis group. The lifetime prevalence was 32.9% in No scoliosis group, and 58.8% in Scoliosis group. According to the gender- and school-grade-adjusted odds ratios (OR), Scoliosis group showed a more than twofold elevated odds of back pain compared to No scoliosis group irrespective of the point or lifetime prevalence of back pain (OR, 2.29; P = 0.009 and OR, 2.10; P = 0.012, respectively). Scoliosis group experienced significantly more severe pain, and of a significantly longer duration with more frequent recurrences in comparison to No scoliosis group. Scoliosis group showed significantly more back pain in the upper and middle right back in comparison to No scoliosis group. These findings suggest that there is a relationship between pain around the right scapula in Scoliosis group and the right rib hump that is common in IS.


Asunto(s)
Dolor de Espalda/epidemiología , Escoliosis/epidemiología , Adolescente , Dolor de Espalda/etiología , Niño , Estudios Transversales , Femenino , Encuestas Epidemiológicas , Humanos , Japón/epidemiología , Masculino , Oportunidad Relativa , Prevalencia , Escoliosis/complicaciones , Índice de Severidad de la Enfermedad , Encuestas y Cuestionarios
9.
Spine (Phila Pa 1976) ; 35(20): E1064-8, 2010 Sep 15.
Artículo en Inglés | MEDLINE | ID: mdl-20802385

RESUMEN

STUDY DESIGN: Case report. OBJECTIVE: To describe an iatrogenic aortic injury by pedicle screw instrumentation during posterior reconstructive surgery of spinal deformity. SUMMARY OF BACKGROUND DATA: Iatrogenic major vascular injuries during anterior instrumentation procedures have been reported by several authors, but there have been few reports regarding iatrogenic major vascular injuries during posterior instrumentation procedures. METHODS: A 57-year-old woman with thoracolumbar kyphosis due to osteoporotic T12 vertebral fracture underwent posterior correction and fusion (T10-L2), using segmental pedicle screw construct concomitant with T12 pedicle subtraction osteotomy. Postoperative routine plain radiographs and computed tomography myelography demonstrated a misplaced left T10 pedicle screw, which was in contact with the posteromedial aspect of the thoracic aorta, and suspected penetration of the aortic wall. The patient underwent removal of the pedicle screw, and repair of the penetrated aortic wall through a simultaneous anterior-posterior approach. RESULT: The patient tolerated the procedure well without neurologic sequelae, and was discharged several days after removal of a left tube thoracostomy. Plain radiographs demonstrated solid fusion at the osteotomy site and no loosening of hardware. Preoperative neurologic symptoms improved completely at 18-months follow-up. CONCLUSION: Use of pedicle screw instrumentation has the potential to cause major vascular injury during posterior spinal surgery, and measures to prevent this complication must be taken. Timely diagnosis and treatment are essential to prevent both early and delayed complications and death.


Asunto(s)
Aorta Torácica/lesiones , Tornillos Óseos/efectos adversos , Cifosis/cirugía , Vértebras Torácicas/cirugía , Femenino , Humanos , Cifosis/diagnóstico por imagen , Cifosis/etiología , Persona de Mediana Edad , Radiografía , Fracturas de la Columna Vertebral/complicaciones , Vértebras Torácicas/diagnóstico por imagen
10.
Eur Spine J ; 17(11): 1441-7, 2008 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-18830637

RESUMEN

A cross-sectional study targeted a total of 43,630 pupils in Niigata City, Japan was performed. The objective was to clarify the present incidence of low back pain (LBP) in childhood and adolescence in Japan. It has recently been recognized that LBP in childhood and adolescence is also as common a problem as that for adults and most of these studies have been conducted in Europe, however, none have so far been made in Japan. A questionnaire survey was conducted using 43,630 pupils, including all elementary school students from the fourth to sixth grade (21,893 pupils) and all junior high students from the first to third year (21,737 pupils) in Niigata City (population of 785,067) to examine the point prevalence of LBP, the lifetime prevalence, the gender differences, the age of first onset of LBP in third year of junior high school students, the duration, the presence of recurrent LBP or not, the trigger of LBP, and the influences of sports and physical activities. In addition, the severity of LBP was divided into three levels (level 1: no limitation in any activity; level 2: necessary to refrain from participating in sports and physical activities, and level 3: necessary to be absent from school) in order to examine the factors that contribute to severe LBP. The validity rate was 79.8% and the valid response rate was 98.8%. The point prevalence was 10.2% (52.3% male and 47.7% female) and the lifetime prevalence was 28.8% (48.5% male and 51.5% female). Both increased as the grade level increased and in third year of junior high school students, a point prevalence was seen in 15.2% while a lifetime prevalence was observed in 42.5%. About 90% of these students experienced first-time LBP during the first and third year of junior high school. Regarding the duration of LBP, 66.7% experienced it for less than 1 week, while 86.1% suffered from it for less than 1 month. The recurrence rate was 60.5%. Regarding the triggers of LBP, 23.7% of them reported the influence of sports and exercise such as club activities and physical education, 13.5% reported trauma, while 55.6% reported no specific triggers associated with their LBP. The severity of LBP included 81.9% at level 1, 13.9% at level 2 and 4.2% at level 3. It was revealed that LBP in childhood and adolescence is also a common complaint in Japan, and these findings are similar to previous studies conducted in Europe. LBP increased as the grade level increased and it appeared that the point and lifetime prevalence in adolescence are close to the same levels as those seen in the adulthood and there was a tendency to have more severe LBP in both cases who experienced pain for more than 1 month and those with recurrent LBP.


Asunto(s)
Envejecimiento/fisiología , Traumatismos en Atletas/epidemiología , Dolor de la Región Lumbar/epidemiología , Actividades Cotidianas , Adolescente , Distribución por Edad , Edad de Inicio , Niño , Enfermedad Crónica/epidemiología , Comorbilidad , Estudios Transversales , Evaluación de la Discapacidad , Femenino , Humanos , Incidencia , Japón/epidemiología , Masculino , Aptitud Física/fisiología , Prevalencia , Recurrencia , Índice de Severidad de la Enfermedad , Distribución por Sexo
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