COVID-19 outbreak prediction using Seq2Seq + Attention and Word2Vec keyword time series data.

As of 2022, COVID-19, first reported in Wuhan, China, in November 2019, has become a worldwide epidemic, causing numerous infections and casualties and enormous social and economic damage. To mitigate its impact, various COVID-19 prediction studies have emerged, most of them using mathematical models and artificial intelligence for prediction. However, the problem with these models is that their prediction accuracy is considerably reduced when the duration of the COVID-19 outbreak is short. In this paper, we propose a new prediction method combining Word2Vec and the existing long short-term memory and Seq2Seq + Attention model. We compare the prediction error of the existing and proposed models with the COVID-19 prediction results reported from five US states: California, Texas, Florida, New York, and Illinois. The results of the experiment show that the proposed model combining Word2Vec and the existing long short-term memory and Seq2Seq + Attention achieves better prediction results and lower errors than the existing long short-term memory and Seq2Seq + Attention models. In experiments, the Pearson correlation coefficient increased by 0.05 to 0.21 and the RMSE decreased by 0.03 to 0.08 compared to the existing method.

Deep similarity analysis and forecasting of actual outbreak of major infectious diseases using Internet-Sourced data.

Perhaps no other generation in the span of recorded human history has endured the risks of infectious diseases as has the current generation. The prevalence of infectious diseases is caused mainly by unlimited contact between people in a highly globalized world. Disease control and prevention (CDC) promptly collect and produce disease outbreak statistics, but CDCs rely on a curated, centralized collection system, and requires up to two weeks of lead time. Consequently, the quick release of disease outbreak information has become a great challenge. Infectious disease outbreak information is recorded and spread somewhere on the Internet much faster than CDC announcements, and Internet-sourced data have shown non-substitutable potential to watch and predict infectious disease outbreaks in advance. In this study, we performed a thorough analysis to show the similarity between the Korean Center of Disease Control (KCDC) infectious disease datasets and three Internet-sourced data for nine major infectious diseases in terms of time-series volume. The results show that many of infectious disease outbreak have strongly related to Internet-sourced data. We analyzed several factors that affect the similarity. Our analysis shows that the increase in the number of Internet-sourced data correlates with the increase in the number of infected people and thus, show the positive similarity. We also found that the greater the number of infectious disease outbreaks corresponds to having a wider spread of outbreak regions, in which it also proves to have higher similarity. We presented the prediction result of infectious disease outbreak using various Internet-sourced data and an effective deep learning algorithm. It showed that there are positive correlations between the number of infected people or the number of related web data and the prediction accuracy. We developed and currently operate a web-based system to show the similarity between KCDC and related Internet-sourced data for infectious diseases. This paper helps people to identify what kind of Internet-sourced data they need to use to predict and track a specific infectious disease outbreak. We considered as much as nine major diseases and three kinds of Internet-sourced data together, and we can say that our finding did not depend on specific infectious disease nor specific Internet-sourced data.

DNA functionalization of colloidal particles via physisorption of azide-functionalized diblock copolymers.

DNA-coated inorganic particles can be prepared simply by physical adsorption of azide-functionalized diblock copolymers (polystyrene-b-poly(ethylene oxide)-azide, PS-b-PEO-N3) onto hydrophobically-modified inorganic particles, followed by strain-promoted azide-alkyne cycloaddition (SPAAC, copper-free click chemistry). This approach is applied to organosilica, silica and titania particles. The DNA-coated colloids are successfully crystallized into colloidal superstructures by a thermal annealing process using DNA-mediated assembly.