RESUMEN
The efficacy of examination of various cytologic material in patients with mesothelioma was analysed. A total of 48 studies were carried out in 24 patients. Examination of transthoracic aspiration material obtained from the tumor and pleural cavity exudate yielded the best results. When mesothelioma of the pleura is suspected, care should be taken to collect material from different areas of the tumor, bearing in mind the significance of discovering different components of the tumor in it. On grounds of study of various cytologic material, a malignant tumor or adenocarcinoma was diagnosed in 43% and mesothelioma in 48% of patients.
Asunto(s)
Mesotelioma/patología , Derrame Pleural/patología , Neoplasias Pleurales/patología , Adulto , Anciano , Femenino , Humanos , Masculino , Mesotelioma/epidemiología , Persona de Mediana Edad , Neoplasias Pleurales/epidemiología , Estudios Retrospectivos , Federación de Rusia/epidemiologíaRESUMEN
The effect of low-frequency ultrasound was studied in different conditions in 197 in vitro experiments according to the histological form of the tumor. It was found that ultrasound with a frequency of 26.6--40.5 kHz, intensity of 2--8 Wt/cm2, and fluctuation amplitude of the end of the smooth cylindrical instrument-wave guide of 60--80 mcm caused destruction of the cells of malignant tumors of humans, whatever the histological form. Experiments with transplanted tumors--Zaidel's ascitic hematoma and sarcoma M-l of rats (202 rats) showed that after transplantation of a tumor cell suspension exposed to sonic waves for 5--7 minutes a tumor does not develop in highly susceptible experimental animals.
Asunto(s)
Adenocarcinoma/terapia , Carcinoma de Células Escamosas/terapia , Neoplasias Hepáticas Experimentales/terapia , Neoplasias Pulmonares/terapia , Sarcoma Experimental/terapia , Terapia por Ultrasonido , Animales , Humanos , Ratas , Células Tumorales CultivadasRESUMEN
In a series of 30,000 cytologic examinations carried out in patients with lung pathology, 20 results were considered false-positive for cancer. However, in 5 of them, malignancy was subsequently confirmed. These data were analysed to identify patterns of lung cancer in which cytologic samples are likely to be misinterpreted as false-positive.