Asunto(s)
Biomarcadores de Tumor/análisis , Carcinoma Basocelular/química , Proteínas Nucleares/análisis , Neoplasias Cutáneas/química , Proteína 1 Relacionada con Twist/análisis , Biopsia , Cadherinas/análisis , Carcinoma Basocelular/secundario , Carcinoma Basocelular/terapia , Transición Epitelial-Mesenquimal , Humanos , Inmunohistoquímica , Neoplasias Pulmonares/secundario , Masculino , Persona de Mediana Edad , Invasividad Neoplásica , Pronóstico , Neoplasias Cutáneas/patología , Neoplasias Cutáneas/terapiaAsunto(s)
Dermatosis Facial/diagnóstico , Linfoma Cutáneo de Células T/diagnóstico , Ácaros , Enfermedades Cutáneas Parasitarias/diagnóstico , Neoplasias Cutáneas/diagnóstico , Animales , Diagnóstico Diferencial , Dermatosis Facial/parasitología , Humanos , Masculino , Persona de Mediana Edad , Enfermedades Cutáneas Parasitarias/parasitologíaAsunto(s)
Anticuerpos Antivirales/uso terapéutico , Hipersensibilidad a las Drogas/tratamiento farmacológico , Herpesvirus Humano 6/inmunología , Inmunoglobulinas Intravenosas/uso terapéutico , Factores Inmunológicos/uso terapéutico , Hipersensibilidad a las Drogas/diagnóstico , Femenino , Humanos , Inmunoglobulinas Intravenosas/administración & dosificación , Factores Inmunológicos/administración & dosificación , Mexiletine/efectos adversos , Persona de Mediana EdadRESUMEN
In 13 of 43 non-beta-hemolysin-producing bovine isolates of Staphylococcus aureus, two truncated beta-hemolysin (hlb) genes were demonstrated by PCR and sequencing, and one truncated hlb gene was located beside the integrase (int) gene of phage origin. The staphylokinase (sak) gene was detected in all 13 isolates in which the truncated hlb genes were detected by PCR. Enterotoxin A (sea) and enterotoxin P (sep) genes were also detected in 5 and 2 of the 13 isolates, respectively. Moreover, the scn and chp genes encoding staphylococcal complement inhibitor (SCIN) and chemotaxis inhibitory protein of S. aureus (CHIPS) were detected in 13 and 4 of the 13 isolates, respectively. The bacteriophage induced by mitomycin C treatment was able to lysogenize one beta-hemolysin-producing isolate of S. aureus, and the sak and scn genes were detected from the lysogenized isolate. These results suggest quadruple or quintuple conversion of hlb, sak, sea (or sep), scn, and chp genes by bacteriophages among non-beta-hemolysin-producing bovine isolates of S. aureus.