ECHOCARDIOGRAPHIC ASPECTS OF ASSESSMENT OF MITRAL INSUFFICIENCY IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION WITH REDUCED LEFT VENTRICULAR EJECTION FRACTION.

OBJECTIVE: The aim is to analyze patients with acute myocardial infarction with reduced ejection fraction in order to determine risk factors for mitral insufficiency. PATIENTS AND METHODS: Materials and methods: The study included 149 patients with acute myocardial infarction. Among the patients, there were 113 males (75.8%) and 36 females (24.2%). The age of the patients ranged from 43 to 86 years. Echocardiography was performed using a Phillips Epiq 7 machine. Patients were examined three times: upon admission to the hospital, after revascularization, and six months after discharge. Patients received transthoracic echocardiography, which was used to determine the presence and degree of mitral regurgitation. RESULTS: Results: According to the results of the study, it was found that the presence of concomitant somatic pathology worsens the course of an acute myocardial infarction, in turn increasing the likelihood of valvular pathology. An increase in left ventricular volume indicators, such as end-diastolic volume, end-systolic volume, end-diastolic index, and the index of contractile function (ejection fraction) contributes to the development of mitral valve insufficiency. CONCLUSION: Conclusions: The presence of mitral regurgitation in patients with acute myocardial infarction and reduced left ventricular ejection fraction worsens the course of the disease and negatively affects the prognosis.

COMPARATIVE ASSESSMENT OF BACTERIAL PERMEABILITY OF A PERSONAL PROTECTIVE RESPIRATORY EQUIPMENT AT DIFFERENT DURATIONS OF ITS CONTINUOUS OPERATION.

OBJECTIVE: The aim: To establish the level of antibacterial protection of the studied personal protective respiratory equipment set and its main components and compare antibacterial resistance of the personal protective respiratory equipment set in the presence and absence of filtering components. PATIENTS AND METHODS: Materials and methods: The proposed methodology for assessing biological protection parameters is based on testing the permeability of personal respiratory protection equipment for bacteria by the method of serial dilutions. Also additional culturing of separate components of the protective set on a separate media is carried out. The experiment was also repeated in the absence of filtering elements and when they were replaced by gauze masks. RESULTS: Results: The use of a fully equipped pneumatic helmet counteracted the penetration of the bacterial aerosol, which was manifested in the absence of growth on the media. The results obtained with the full configuration, as well as the indicators of the spread of bacteria when removing the filter elements and replacing them with gauze masks, showed that the device creates sufficient positive air pressure inside. The latter becomes a restraining factor that does not allow microorganisms to penetrate through the lower circuit. CONCLUSION: Conclusions: Increasing the duration of continuous operation of the conceptual model up to 24 hours, increasing the bacterial load on the filters do not lead to a deterioration in the properties of antibacterial protection. Bacterial aerosol did not penetrate into the inner space of pneumatic helmet.