Asunto(s)
Eosinofilia/etiología , Foliculitis/etiología , Síndrome de Job/complicaciones , Síndrome de Job/diagnóstico , Enfermedades Cutáneas Vesiculoampollosas/etiología , Niño , Humanos , Inmunoglobulina E/sangre , Síndrome de Job/genética , Recuento de Leucocitos , Masculino , Mutación , Factor de Transcripción STAT3/genéticaRESUMEN
BACKGROUND: Horizontal scalp biopsy is a better method to use when evaluating hair disorders, but an accurate diagnosis requires quantitative data regarding normal hair counts to be used as a control, which are currently available only for Caucasians, African Americans, Koreans, and Iranians. OBJECTIVES: To evaluate scalp hair counts in the Taiwanese population. METHODS: Two 4-mm punch biopsies were taken from clinically normal-looking scalp skin of 31 patients who underwent scalp surgery for non-hair-loss disorders. Punch biopsy specimens were sectioned horizontally at the sebaceous gland level and the number of follicular units, terminal hairs including anagen and telogen hairs, and vellus hairs were counted and compared with other published data. The numbers of hairs were also compared between the sexes, different age groups, and different anatomical locations of the scalp. RESULTS: The average counts of total hairs, terminal hairs, vellus hairs, and follicular units per 4-mm punch scalp skin were 21.3, 20.5, 0.8, and 9.4, respectively. The mean ratio of anagen hair to telogen hair was 91.6:8.4 and of terminal hair to vellus hair was 25.3:1. The average density of hair follicles was 1.69 mm(2). The mean counts of terminal hairs, total hairs, follicular units, and hair follicles/mm(2) were significantly different between different age groups. CONCLUSION: Differences in hair count parameters were recognized between different ethnic groups. Parameters of hair density established in the Taiwanese population will provide clinicians with useful reference data for the evaluation of hair disorders in Asians.
Asunto(s)
Pueblo Asiatico , Cabello/citología , Cuero Cabelludo/anatomía & histología , Adulto , Factores de Edad , Biopsia , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Factores Sexuales , Taiwán , Adulto JovenAsunto(s)
Neoplasias Encefálicas/cirugía , Hemorragias Intracraneales/cirugía , Linfoma de Células B Grandes Difuso/cirugía , Siembra Neoplásica , Neoplasias Cutáneas/secundario , Derivación Ventriculoperitoneal/efectos adversos , Anciano de 80 o más Años , Neoplasias Encefálicas/patología , Humanos , Hemorragias Intracraneales/etiología , Linfoma de Células B Grandes Difuso/patología , MasculinoAsunto(s)
Lupus Eritematoso Sistémico/complicaciones , Tuberculosis Cutánea/etiología , Tuberculosis Miliar/etiología , Enfermedad Aguda , Antituberculosos/uso terapéutico , Combinación de Medicamentos , Femenino , Humanos , Isoniazida/uso terapéutico , Lupus Eritematoso Sistémico/tratamiento farmacológico , Persona de Mediana Edad , Pirazinamida/uso terapéutico , Rifampin/uso terapéutico , Esteroides/uso terapéutico , Tuberculosis Cutánea/tratamiento farmacológico , Tuberculosis Cutánea/patología , Tuberculosis Miliar/tratamiento farmacológico , Tuberculosis Miliar/patologíaAsunto(s)
Antineoplásicos/uso terapéutico , Carcinoma de Pulmón de Células no Pequeñas/tratamiento farmacológico , Neoplasias Pulmonares/tratamiento farmacológico , Quinazolinas/efectos adversos , Enfermedades Cutáneas Vasculares/inducido químicamente , Vasculitis/inducido químicamente , Antineoplásicos/efectos adversos , Biopsia con Aguja , Carcinoma de Pulmón de Células no Pequeñas/patología , Carcinoma de Pulmón de Células no Pequeñas/cirugía , Estudios de Seguimiento , Gefitinib , Humanos , Inmunohistoquímica , Extremidad Inferior , Neoplasias Pulmonares/patología , Neoplasias Pulmonares/cirugía , Masculino , Persona de Mediana Edad , Necrosis/inducido químicamente , Necrosis/tratamiento farmacológico , Invasividad Neoplásica/patología , Estadificación de Neoplasias , Prednisolona/administración & dosificación , Quinazolinas/uso terapéutico , Medición de Riesgo , Enfermedades Cutáneas Vasculares/tratamiento farmacológico , Enfermedades Cutáneas Vasculares/patología , Resultado del Tratamiento , Vasculitis/tratamiento farmacológico , Vasculitis/patologíaRESUMEN
Peripheral blood hypereosinophilia reflects various underlying disorders. However, its thromboembolic consequences are not often highlighted. We report a case of acute pulmonary embolism in a 42 year-old male prisoner hospitalized for erythrodermic psoriasis who presented with generalized edema and shortness of breath. Severe eosinophilia (absolute eosinophil count 6232/ΜL) was also noted. Although severe psoriasis can be associated with eosinophilia and metabolic syndrome, acute pulmonary embolism is very rare in these patients. Immobilization secondary to severe psoriatic arthritis and prolonged use of leg cuffs can exacerbate the formation of thromboembolism. Although investigating the underlying causes of eosinophilia is important, we would like to highlight the importance of being aware of thromboembolic events, especially in patients with other thrombotic risk factors.