Neuroendocrine adenoma of the middle ear presented as paragaglioma: a case report.

BACKGROUND: Neuroendocrine adenoma of the middle ear (NAME) is a rare benign glandular tumor with neuroendocrine differentiation arising from the middle ear mucosa. The common symptoms and clinical findings of this tumor are usually non-specific. When the tumor appears as a reddish retrotympanic mass, it can be misdiagnosed to be a paraganglioma. CASE DESCRIPTION: A 38-year-old male presented with a 12-month history of left ear ​​fullness and tinnitus. Otoscopy revealed a reddish retrotympanic mass with an intact tympanic membrane. The imaging demonstrated a soft tissue mass adjacent to the eardrum and the ossicles, compatible with a paraganglioma. The mass was surgically removed through a posterior tympanotomy. The histological and immunohistochemical examination showed the specimen to be a neuroendocrine adenoma. Four years after the operation, the patient remains without any sign of recurrence. CONCLUSION: NAME is a rare tumor, mimicking tympanic paraganglioma, while its final diagnosis is only provided by histological and immunohistochemical analysis. HIPPOKRATIA 2017, 21(4): 201-203.

Intramuscular haemangioma of the levator anguli oris: a rare case.

Intramuscular haemangiomas are benign malformations of blood vessels occurring in skeletal muscles. Because of the rarity of these lesions, their deep location and variable clinical presentation, they often pose diagnostic difficulties. We herein present the first reported case of intramuscular haemangioma occurring in the levator anguli oris muscle. A 26-year-old man was referred to our Department for evaluation and management of a progressive swelling of the right cheek. Based mainly on the imaging findings, a preoperative diagnosis of intramuscular haemangioma was made and surgery was performed. During intervention, a highly vascular soft tissue mass was identified within the levator anguli oris muscle. The lesion was completely removed via an intraoral approach, and histopathological examination showed an intramuscular haemangioma.

Huge mastoid congenital cholesteatoma in a 52-year-old patient.

Congenital cholesteatoma may arise in various locations within the temporal bone. The rarest site of origin is the mastoid process. We report an unusual case of a 52-year-old man with mastoid congenital cholesteatoma that manifested as a persistent ear discharge. The preoperative suspicion was based on the imaging findings and the patient's history. A simple mastoidectomy was conducted and the cholesteatoma was completely removed while using facial nerve monitoring. Although rare, mastoid congenital cholesteatoma can be considered as an alternative in the differential diagnosis of persistent otorrhea.

Basaloid squamous cell carcinoma of the tonsil.

Basaloid squamous cell carcinoma (BSCC) is a rare and aggressive variant of squamous cell carcinoma that mainly arises in the upper aerodigestive tract. The tonsil is a rare site of BSCC development and only fourteen cases have been reported in the international literature. We report here on the case of a 56-year-old man who presented with mild dysphagia. Computed tomography and examination of the oropharynx revealed a suspicious-looking, bulky mass on the right tonsil. Histopathological examination confirmed the presence of BSCC. The patient had cervical lymph node metastases and pulmonary metastases and was treated with chemotherapy and concurrent radiation. Despite the metastases the patient is still alive 3 years after the initial diagnosis.