RESUMEN
Global climate governance has entered the era of carbon neutrality, as a growing number of countries have set the goal of carbon neutrality for long-term emissions reduction toward the mid-21st century. In 2020, China also pledged itself to the goal of carbon neutrality, which creates an urgent demand for this country to establish a systematic and integrated national climate governance system. Against this background, this paper conducts a systematic literature review of climate governance systems from the perspectives of top-level design and the governance paradigm to bring insights into climate governance toward carbon neutrality. The results show that although there are interactions between decarbonization and other environmental, social and economic fields, research gaps still exist when enhancing climate governance toward carbon neutrality. For example, issues regarding incorporating climate factors into the overall economic and social layout, strengthening the capacity of data collection relevant to climate adaptation, integrating climate mitigation and adaption actions, as well as connecting domestic climate governance and international cooperation, need to be further addressed. In addition, within the national governance system, studies combining both regional and sectoral concerns and the intertemporal dynamic allocation mechanism need to be further addressed when China decomposes its national climate target. Moreover, the division of power between the central government and local government, as well as the communication scheme between government and non-state actors, also turns out to be important for effective governance. Based on this analysis, policy implications are further proposed for China's formulation and implementation of long-term strategies of climate governance toward carbon neutrality.
RESUMEN
Traditionally, the anteroventral periventricular (AVPV) nucleus has been the brain area associated with luteinizing hormone (LH) surge secretion in rodents. However, the role of the other population of hypothalamic kisspeptin neurons, in the arcuate nucleus (ARC), has been less well characterized with respect to surge generation. Previous experiments have demonstrated ARC kisspeptin knockdown reduced the amplitude of LH surges, indicating that they have a role in surge amplification. The present study used an optogenetic approach to selectively stimulate ARC kisspeptin neurons and examine the effect on LH surges in mice with different hormonal administrations. LH level was monitored from 13:00 to 21:00 h, at 30-minute intervals. Intact Kiss-Cre female mice showed increased LH secretion during the stimulation period in addition to displaying a spontaneous LH surge around the time of lights off. In ovariectomized Kiss-Cre mice, optogenetic stimulation was followed by a surge-like secretion of LH immediately after the stimulation period. Ovariectomized Kiss-Cre mice with a low dose of 17ß-estradiol (OVX+E) replacement displayed a surge-like increase in LH release during period of optic stimulation. No LH response to the optic stimulation was observed in OVX+E mice on the day of estradiol benzoate (EB) treatment (day 1). However, after administration of progesterone (day 2), all OVX+E+EB+P mice exhibited an LH surge during optic stimulation. A spontaneous LH surge also occurred in these mice at the expected time. Taken together, these results help to affirm the fact that ARC kisspeptin may have a novel amplificatory role in LH surge production, which is dependent on the gonadal steroid milieu.
Asunto(s)
Núcleo Arqueado del Hipotálamo , Estradiol/farmacología , Hormona Luteinizante/metabolismo , Neuronas/efectos de los fármacos , Animales , Núcleo Arqueado del Hipotálamo/citología , Núcleo Arqueado del Hipotálamo/efectos de los fármacos , Núcleo Arqueado del Hipotálamo/metabolismo , Estradiol/metabolismo , Femenino , Humanos , Kisspeptinas/genética , Kisspeptinas/metabolismo , Ratones , Ratones Transgénicos , Neuronas/metabolismo , Optogenética , Ovariectomía , Ovario/metabolismo , Progesterona/farmacologíaRESUMEN
Due to economic development and population growth, the water shortage in China has gradually become increasingly severe. In this paper, by developing an environmentally expanded input-output (IO) model, water footprint in China during 2002-2012 is calculated from the perspective of final demand. Furthermore, a structural decomposition analysis (SDA) model is used to study the driving factors of the water footprint of rural and urban household consumption, gross fixed capital formation and exports. The findings indicate that: 1) the water footprint driven by final demand in China increased by 18.3% during 2002-2012, reaching 617.68â¯billionâ¯m3 in 2012, of which urban household consumption accounts for the highest proportion. 2) Of the different sectors, agricultural commodities have the highest water footprint, accounting for 35% of national water footprint in 2012. 3) In terms of the driving factors, water efficiency inhibits the increase of water footprint regardless of final demand types, while GDP per capita makes a great contribution to its rise. 4) As for rural household consumption, the most important driving factor is the inhibition effects of consumption pattern in water footprint. For urban household consumption, the water footprint is inhibited by consumption pattern but promoted by production structure during 2002-2010. However, it is no longer the case during 2010-2012 that consumption pattern becomes a promoting factor, with production structure being inhibiting one. 5) Regarding gross fixed capital formation, its water footprint increase driven by consumption pattern is only 12.4â¯billionâ¯m3 during 2007-2010. As for exports, consumption pattern causes the decline of water footprint after 2005 and the overall water footprint of exports declines during 2007-2012. Finally, this paper provides policy implications with respect to the promotion of China's water footprint conservation.