[Laboratory evaluation of the effectiveness and safety of the Chairside Light Whitening System fläsh]. / Laboratornaya otsenka effektivnosti i bezopasnosti otbelivayushchei sistemy Chairside Light Whitening System fläsh.

THE AIM OF THE STUDY: Optimization of methods for treating dental discoloration using whitening systems based on hydrogen peroxide by laboratory studying their chemical properties. MATERIAL AND METHODS: The effectiveness of the bleaching system was assessed by quantitatively assessing the color change of model samples of hydroxyapatite (HAP) in the CIE L*a*b* system on a Spectron-M color analyzer after exposure to coloring food media. Safety assessment was carried out on samples made from teeth removed according to indications. RESULTS: The results of laboratory tests allow us to conclude that the Chairside Light Whitening System professional teeth whitening system fläsh. (WHITEsmile GmbH, Germany) has high whitening efficiency with a whitening degree of ~84%, which significantly exceeds the norm of GOST R 702.3.004-2021. the microhardness of the enamel of samples exposed to the whitening gel for 15 minutes changes extremely little. After exposure of the studied samples to the Chairside Light Whitening System fläsh whitening system for 45 minutes, an increase in digital microhardness indicators is observed, which indicates the dynamics of processes demineralizing the hard tooth structure. CONCLUSIONS: Chairside Light Whitening System fläsh professional teeth whitening system has high whitening efficiency with minimal impact on the teeth structure and high safety.

[Spectrophotometric assessment of photodynamic teeth bleaching]. / Otsenka effektivnosti fotodinamicheskogo otbelivaniya zubov.

THE AIM: Clinical analysis of the effectiveness of photodynamic tooth whitening according to the spectrophotometric method. MATERIAL AND METHODS: Photodynamic tooth whitening was performed in 35 patients aged 20-45 years, on the teeth of the frontal group. To record the optical characteristics of enamel, the spectrophotomerism method was used. RESULTS: The study reliably shows that the average change in color saturation «C¼ ranged from 0.5 to 2 units. The optical characteristic of luminosity "L" before and after photodynamic exposure remained within the limits of healthy enamel, and the optical characteristic of whiteness on the scale of whitened teeth was 2 units. CONCLUSION: The method of photodynamic therapy can be used in dental practice to conduct a teeth whitening procedure.

Protein Complex NDC80: Properties, Functions, and Possible Role in Pathophysiology of Cell Division.

Mitotic division maintains genetic identity of any multicellular organism throughout an entire lifetime. Each time a parent cell divides, chromosomes are equally distributed between the daughter cells due to the action of mitotic spindle. Mitotic spindle is formed by the microtubules that represent dynamic polymers of tubulin protein. Spindle microtubules are attached end-on to kinetochores - large multi-protein complexes on chromosomes. This review focuses on the four-subunit NDC80 complex, one of the most important kinetochore elements that plays a major role in the attachment of assembling/disassembling microtubule ends to the chromosomes. Here, we summarize published data on the structure, properties, and regulation of the NDC80 complex and discuss possible relationship between changes in the expression of genes coding for the NDC80 complex components, mitotic disorders, and oncogenesis with special emphasis on the diagnostic and therapeutic potential of NDC80.

[Analysis of photosensitizer gel penetration through the teeth structure]. / Analiz glubiny proniknoveniia gelia fotosensibilizatora v strukturu tkanei zubov.

As a result of the studies carried out on 20 extracted frontal teeth it was reliably shown that after 10 minutes the concentration of the photosensitizer in enamel at full depth reached values sufficient for performing photodynamic teeth whitening. At the same time, the penetration of the photosensitizer into the deep layers of dentin was not detected which allows to carry out the photodynamic bleaching procedure only within the enamel and enamel-dentine boundary, thus not affecting the pulp of the tooth.

[Surgical treatment of patients with drug abuse and mandible necrosis].

The article describes clinical and radiological classification of osteonecrosis of the mandible in patients with drug dependence, surgical options presented on the basis of classification proposed. Clinical case of simultaneous application of individual plate of nikelid titanium in patient with osteonecrosis of the mandible is presented.