RESUMEN
The paper presents the results of investigating the impact of chemical ambient air pollution on congenital morphogenetic variants (CMVs) in 4-7-year-old children. CMVs have been ascertained to depend on the pattern and level of chemical ambient air pollution. Mild morphogenetic disorders develop in the conceptive, organogenetic, and early fetogenetic periods.
Asunto(s)
Contaminantes Atmosféricos , Desarrollo Embrionario/efectos de los fármacos , Desarrollo Fetal/efectos de los fármacos , Efectos Tardíos de la Exposición Prenatal/inducido químicamente , Contaminantes Atmosféricos/química , Contaminantes Atmosféricos/toxicidad , Niño , Preescolar , Desarrollo Embrionario/genética , Femenino , Desarrollo Fetal/genética , Humanos , Masculino , Embarazo , Efectos Tardíos de la Exposición Prenatal/epidemiología , Efectos Tardíos de la Exposición Prenatal/genética , Análisis de RegresiónRESUMEN
Adaptive capacities were studied in 6-7-year-ol apparently healthy children in relation to the number of congenital morphogenetic variants (CMVs). The most markedly reduced adaptive capacities were revealed in children with 5 CMVs or more.
Asunto(s)
Adaptación Fisiológica/efectos de los fármacos , Adaptación Psicológica/efectos de los fármacos , Contaminantes Atmosféricos/análisis , Sistema Nervioso Autónomo , Variación Genética , Morfogénesis/efectos de los fármacos , Adaptación Fisiológica/genética , Contaminantes Atmosféricos/efectos adversos , Sistema Nervioso Autónomo/efectos de los fármacos , Sistema Nervioso Autónomo/crecimiento & desarrollo , Sistema Nervioso Autónomo/fisiología , Niño , Monitoreo del Ambiente , Humanos , Metalurgia , Morfogénesis/genética , Federación de Rusia , Población UrbanaRESUMEN
The study was undertaken to examine the basic frequencies of congenital morphogenetic variants (CMVs) among preschool children. The basic frequencies were valid if the population frequency was more than 2-4 %. The least valid frequencies were characteristic of rare signs at a frequency of less than 1%. It is suggested that rare signs be integrated into an individual group and then their average be compared.
Asunto(s)
Enfermedades Ambientales/epidemiología , Morfogénesis/genética , Niño , Preescolar , Femenino , Frecuencia de los Genes , Humanos , Masculino , Federación de Rusia/epidemiologíaRESUMEN
Congenital morphogenetic variants (CMGV) and anthropometric indices as markers of individual development were analyzed in 4-7-year-old children, visiting the kindergarten, in 2 Magnitogorsk districts with varying chemical ambient air pollution. The basic characteristics of CMGV were found to be stable in relation to gender. The study indicated that the average number of CMGV, rare CMGV (at a rate of not greater than 1%) and individual CMGV depended on the degree of chemical ambient air pollution. It was larger in a more polluted area. Lower anthropometric indices (height and body weight) were observed in boys living in a more polluted area.
Asunto(s)
Desarrollo Infantil , Industrias , Población Urbana , Antropometría , Niño , Femenino , Humanos , MasculinoRESUMEN
The results of a medical genetic study of the spread of congenital morphogenetic types (CMGT) among 3-7-year-old children living in Magnitogorsk whose territory is highly polluted with chemical compounds are presented. In Magnitogorsk, the mean of CMGT cases per child is 2.89, which is much greater than the respective values for environmentally favorable cities and towns in Russia. The most common signs are as follows: diastema (137.79 cases per 1000 children), clinodactyly (135.98 per 1000), epicanthus (122.44 per 1000), and wide umbilical ring (110.71 per 1000).