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1.
Annu Int Conf IEEE Eng Med Biol Soc ; 2019: 6314-6317, 2019 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-31947286

RESUMEN

Thermal imaging is used in medical diagnosis and preventive screening, e.g. breast cancer, cardiovascular disease, and orthopedics. Segmentation algorithms fail to recognize body parts of interest when the temperature difference between the body parts and the background is insufficient. We propose to perform segmentation in two stereoscopically acquired RGB images and to triangulate corresponding points extracted from those images into world coordinates. The thereby acquired world coordinates are projected into the thermal image plane for a more robust segmentation result. Our worked example is the segmentation of human hands. The extension of the thermal setup with two additional RGB cameras improves segmentation in our particular case, but could also make segmentation of other body parts in thermal images more robust. Comparing significant points like fingertips and the junctions between the fingers and the metacarpus, we come up with an average deviation of 1.03 pixel ± 0.82 pixel in x-axis direction and 1.04 pixel ± 0.62 pixel in y-axis direction, roughly corresponding to a mean Euclidean distance of 1.4 mm on the hands.


Asunto(s)
Algoritmos , Mano/diagnóstico por imagen , Interpretación de Imagen Asistida por Computador , Termografía , Humanos
2.
Biomed Tech (Berl) ; 62(2): 213-223, 2017 Apr 01.
Artículo en Inglés | MEDLINE | ID: mdl-28306515

RESUMEN

This paper presents a decentralized safety concept for networked intensive care setups, for which a decentralized network of sensors and actuators is realized by embedded microcontroller nodes. It is evaluated for up to eleven medical devices in a setup for automated acute respiratory distress syndrome (ARDS) therapy. In this contribution we highlight a blood pump supervision as exemplary safety measure, which allows a reliable bubble detection in an extracorporeal blood circulation. The approach is validated with data of animal experiments including 35 bubbles with a size between 0.05 and 0.3 ml. All 18 bubbles with a size down to 0.15 ml are successfully detected. By using hidden Markov models (HMMs) as statistical method the number of necessary sensors can be reduced by two pressure sensors.


Asunto(s)
Alarmas Clínicas , Cuidados Críticos/métodos , Circulación Extracorporea/métodos , Monitoreo Fisiológico/métodos , Síndrome de Dificultad Respiratoria/diagnóstico , Síndrome de Dificultad Respiratoria/terapia , Terapia Asistida por Computador/métodos , Animales , Retroalimentación Fisiológica , Humanos , Monitoreo Fisiológico/instrumentación , Seguridad del Paciente , Reconocimiento de Normas Patrones Automatizadas/métodos , Resultado del Tratamiento
3.
Biomed Tech (Berl) ; 62(2): 199-212, 2017 Apr 01.
Artículo en Inglés | MEDLINE | ID: mdl-28121615

RESUMEN

A new concept is presented for cooperative automation of mechanical ventilation and extracorporeal membrane oxygenation (ECMO) therapy for treatment of acute respiratory distress syndrome (ARDS). While mechanical ventilation is continuously optimized to promote lung protection, extracorporeal gas transfer rates are simultaneously adjusted to control oxygen supply and carbon dioxide removal using a robust patient-in-the-loop control system. In addition, the cooperative therapy management uses higher-level algorithms to adjust both therapeutic approaches. The controller synthesis is derived based on the introduced objectives, the experimental setup and the uncertain models. Finally, the autonomous ARDS therapy system capabilities are demonstrated and discussed based on in vivo data from animal experiments.


Asunto(s)
Oxigenación por Membrana Extracorpórea/métodos , Pulmón/fisiopatología , Modelos Biológicos , Respiración Artificial/métodos , Síndrome de Dificultad Respiratoria/fisiopatología , Síndrome de Dificultad Respiratoria/terapia , Mecánica Respiratoria , Animales , Terapia Combinada/instrumentación , Terapia Combinada/métodos , Simulación por Computador , Diseño de Equipo , Análisis de Falla de Equipo , Oxigenación por Membrana Extracorpórea/instrumentación , Retroalimentación Fisiológica , Humanos , Respiración Artificial/instrumentación , Síndrome de Dificultad Respiratoria/diagnóstico , Integración de Sistemas , Terapia Asistida por Computador/instrumentación , Terapia Asistida por Computador/métodos , Resultado del Tratamiento
4.
Biomed Tech (Berl) ; 54(5): 289-97, 2009 Oct.
Artículo en Alemán | MEDLINE | ID: mdl-19807292

RESUMEN

In some cases of severe acute respiratory distress syndrome, hypoxemia occurs despite optimized conservative therapy; however, extracorporeal membrane oxygenation (ECMO) can assure sufficient gas exchange. To increase safety and reliability of devices, the oxygenator design was optimized integrating new plasma-resistant composite membranes and new blood pumps are used with longer durability and reduced blood cell damage. Another approach is the use of an arterio-venous pumpless extracorporeal lung assist (pECLA) using an oxygenator with reduced pressure drop to simplify management and to avoid pump-related complications. First attempts were made to integrate basic control and safety concepts in ECMO circuits, but this does not seem to be sufficient to overcome the specific problems of ECMO (long-term use and limited supervision of the intensive care unit). The integration of sophisticated automated control and safety concepts in combination with revised ECMO circuits could allow a more reliable application of ECMO of the intensive care unit without continuous observation by a perfusionist. Easier intra- and interhospital transfer of patients with running ECMO would be another advantage.


Asunto(s)
Diseño Asistido por Computadora , Oxigenación por Membrana Extracorpórea/instrumentación , Hipoxia/rehabilitación , Modelos Biológicos , Terapia Asistida por Computador/instrumentación , Terapia Asistida por Computador/métodos , Simulación por Computador , Diseño de Equipo , Análisis de Falla de Equipo , Seguridad de Equipos/instrumentación , Seguridad de Equipos/métodos , Oxigenación por Membrana Extracorpórea/efectos adversos , Oxigenación por Membrana Extracorpórea/métodos , Retroalimentación , Humanos
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