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1.
Eur Rev Med Pharmacol Sci ; 27(18): 8523-8530, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37782168

RESUMEN

OBJECTIVE: We aimed to investigate the relationship between intraoperative body temperature and thiol/disulfide balance in geriatric patients scheduled for elective transurethral prostate resection surgery with spinal anesthesia. PATIENTS AND METHODS: 71 patients classified as categories 1 and 2, according to American Society of Anesthesiologists (ASA) classification, were included in the study. The core temperature of the patients was recorded in the operating room after monitoring, at 5 and 30 minutes after spinal anesthesia. Total thiols, native thiols, disulfide amounts, disulfide/native thiol, disulfide/total thiol, and native thiol/total thiol were calculated as percentages after monitorization (Tpreoperative) and at 60 minutes after spinal anesthesia (Tintraoperative). RESULTS: The disulfide levels in the Tintraoperative period (29±8.9 mmol/L) were higher than the disulfide levels measured in the Tpreoperative period (18.2±8.8 mmol/L) (p<0.001). In the Tpreoperative period, the disulfide/native thiol (%) level was 4.6±2, while the disulfide/total thiol (%) level was 4.2±1.6. In the Tintraoperative period, the disulfide/native thiol (%) level was 8±2.3, while the disulfide/total thiol (%) level was 6.8±1.7. Native thiol/total thiol (%) levels for the Tpreoperative and Tintraoperative periods were 91.5±3.3 mmol/L and 86.3±3.4 mmol/L, respectively. A correlation was found between native, total thiol levels and patient age in the Tpreoperative and Tintraoperative periods. CONCLUSIONS: Oxidative stress can be reduced in geriatric patients with the possibility of developing involuntary perioperative hypothermia by regularly monitoring body temperature and applying warming techniques.


Asunto(s)
Anestesia Raquidea , Resección Transuretral de la Próstata , Masculino , Humanos , Anciano , Temperatura Corporal , Disulfuros , Compuestos de Sulfhidrilo , Estrés Oxidativo , Biomarcadores
2.
Clin Exp Obstet Gynecol ; 39(2): 168-70, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-22905456

RESUMEN

PURPOSE OF INVESTIGATION: To evaluate the effectiveness of bilateral uterine arteries and ovarian artery ligation followed by B-Lynch compression suturing in controlling atonic postpartum hemorrhage. METHODS: In this retrospective study, the data of eight patients that had uterine atony during cesarean section and treated by bilateral uterine and ovarian artery ligation followed by B-Lynch compression suturing during the period from February 2009 to September 2010 were collected and analyzed. RESULTS: Eight cases were treated by the above protocol; the average age of the patients was 25.25 +/- 5.09 years, and the mean gestational age was 35.75 +/- 3.80 weeks. Seven of the patients were primiparous. They were hospitalized on average 5.25 +/- 2.31 days. The mean operation time was 61.25 +/- 24.60 minutes and mean estimated blood loss was 2787.5 +/- 1573.38 ml. Internal iliac artery ligation was necessary in one patient only. Hysterectomy was not performed in any of the patients. Five patients had intraoperative or postoperative blood transfusion. CONCLUSION: The addition of uterine artery and ovarian artery ligation to the B-Lynch suture may be considered as a major hemostatic step before proceeding to hysterectomy in cases of uterine atony bleeding, and all gynecologic surgeons should be familiar with it.


Asunto(s)
Ovario/irrigación sanguínea , Hemorragia Posparto/terapia , Arteria Uterina/cirugía , Inercia Uterina , Adulto , Arterias , Pérdida de Sangre Quirúrgica , Femenino , Hemostasis Quirúrgica , Humanos , Histerectomía , Ligadura , Hemorragia Posparto/fisiopatología , Embarazo , Estudios Retrospectivos , Suturas , Inercia Uterina/fisiopatología , Adulto Joven
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