Efficacy of Labial Split-Thickness Eversion Periosteoplasty for Soft Tissue Management in Posterior Mandibular Horizontal Ridge Augmentation Procedures: A Prospective Clinical Study.

Purpose: To evaluate the efficacy of split-thickness labial eversion periosteoplasty (EPP) for soft tissue closure in horizontal ridge augmentation of posterior mandibular regions using a bone shell onlay grafting technique. Materials and Methods: Sixteen patients (12 female and 4 male; mean age: 46.2 ± 8.7 years) with 18 horizontal bone defects in posterior mandibular regions were included for lateral onlay bone grafting using the bone shell technique. After lateral bone augmentation, the EPP was used for soft tissue closure and was prospectively followed up for wound healing efficacy using a modified scoring index. The scoring index included dichotomous (yes: 0 / no: 1) evaluation of the following items: (1) bleeding on palpation or spontaneously, (2) tissue color difference, (3) presence of hematoma, (4) presence of granulation tissue, (5) incomplete incision margin closure, (6) dehiscence with visible augmentation material, (7) presence of exudation, and (8) presence of suppuration. In addition, a visual analog scale (VAS) was used to quantify and record the amount of pain and swelling (0 = no pain/swelling and 5 = severe pain/swelling); VAS scores of 0, 1, and 2 were rated as 1 in the dichotomous scoring index, and VAS scores of 3, 4, and 5 were rated as 0. A summarized wound healing score consisting of all 10 items was assessed at days 2, 7, and 14 and at months 1 and 4 postoperatively, including a comparison of the follow-up evaluations. Results: The summarized healing score increased significantly (P < .01) between day 2 (score: 6.6 ± 1.1) and day 7 (score: 8.9 ± 1.0) but showed little difference between day 14 (score: 9.6 ± 0.6) and the 1- and 4-month follow-ups (score: 10.0 ± 0). There was no wound dehiscence and no incomplete incision margin adaptation. For the individual parameters evaluated, bleeding on palpation, hematoma, and exudation were the most frequent side effects at day 2 at 50%, 100%, and 22.2%, respectively, and at day 7 at 16.7%, 55.6%, and 22.2%, respectively. The average pain score and the swelling/edema score were initially 4.0 ± 0 and 3.0 ± 0.77 on day 2, with a significant decrease (P < .001) by day 7 (pain: 2.0 ± 0; edema/swelling: 2.0 ± 0.59) and day 14 (pain: 1.0 ± 0.42; edema/swelling: 2.0 ± 0.79) and complete absence (score: 0) at months 1 and 4. Conclusions: Labial split-thickness EPP facilitates flap advancement and enables tight soft tissue coverage in large horizontal posterior mandibular bone augmentations as a result of offset double-layer wound closure. Although this procedure is shown to be surgically demanding, the postoperative complication rate may be reduced significantly.

Clinical, radiographic, and histological/histomorphometric analysis of maxillary sinus grafting with deproteinized porcine or bovine bone mineral: A randomized clinical trial.

OBJECTIVE: The present study aimed to compare histomorphometrically evaluated new bone formation, radiographically measured graft stability, and clinical implant outcome between maxillary sinus grafting with either deproteinized porcine bone mineral (DPBM) or deproteinized bovine bone mineral (DBBM). MATERIALS AND METHODS: Thirty maxillary sinuses were initially included and randomly assigned to the test group (TG; DPBM, n = 15) or control group (CG; DBBM, n = 15). After a healing period (6 months), axially retrieved bone biopsies of the molar region were used for histological/histomorphometric analysis of new bone formations. Additionally, radiographically measured graft stability and clinical implant outcome were assessed. RESULTS: Twenty-three sinus sites with 10 sinuses of the TG and 13 of the CG were ultimately available for data and statistical analysis. In the TG, a slightly, but yet significantly (p = .040) higher proportion of new bone formation (TG: 27.7 ± 5.6% vs. CG: 22.9 ± 5.1%) and a lesser (p = .019) amount of connective (non-mineralized) tissue (TG: 47.5 ± 9.5% vs. CG: 56.1 ± 9.5%) was found than in the CG. However, both xenografts showed comparable (n.s.) residual bone graft (TG: 23.7 ± 7.2% vs. CG: 21.1 ± 9.85.6%), bone-to-graft contacts (TG: 26.2 ± 9.8% vs. CG: 30.8 ± 13.8%), similar graft height reduction over time (TG: 12.9 ± 6.7% CG: 12.4 ± 5.8%) and implant survival/success rate (100%). At the 3-year post-loading evaluation, the peri-implant marginal bone loss (TG: 0.52 ± 0.19 mm; CG: 0.48 ± 0.15 mm) and the peri-implant health conditions (TG: 87.5%/CG: 81.2%) did not differ between implants inserted in both xenografts used. CONCLUSIONS: The use of DPBM or DBBM for maxillary sinus augmentation is associated with comparable bone formation providing stable graft dimension combined with healthy peri-implant conditions.

Transsinusoidal lateral nasal floor augmentation for implant placement in the atrophic premaxilla: A within-patient, 5-year, prospective comparative study.

OBJECTIVES: To evaluate the clinical outcome for implants placed with transsinusoidal-lateral nasal cavity augmentation (NA) compared to implants placed in maxillary sinus augmentation (SA). MATERIALS AND METHODS: In 28 atrophic edentulous maxillary regions (14 patients bi-maxillary), a lateral window approach was used to perform transsinusoidal-lateral NA (TSLNA) combined with maxillary SA. After healing period of about 6 months, each patient received bimaxillary one anterior implant located in the pre-maxilla having lateral NA and 2-3 implants in the maxillary posterior region with SA. In a prospective follow-up evaluation, clinical implant outcome (survival/success rates) and peri-implant health (mucositis/peri-implantitis) were assessed and compared between implants placed in TSLNA (n = 28) and SA (n = 58). RESULTS: At the year-1, year-3, and year-5 evaluation, neither patient-based nor implant-based comparisons revealed differences for marginal bone level reduction between implants placed in TSLNA (5-year overall: 1.11 ± 0.26 mm) and SA (5-year overall: 1.07 ± 0.30 mm), although with a significant (p < .001) continuous reduction over the observation time. At the year-5 evaluation, all implants (n = 86) and restorations (n = 14) were still in situ (survival 100%) and showed an implant-based incidence of peri-implant mucositis/peri-implantitis of 14.3%/0% in TSLNA and 6.9%/3.4% in SA corresponding to 21.4%/0% and 28.6%/7.1% for implant-based evaluation. In addition, the implant success rate did not differ between NA and SA at implant- (100%/ 98.8%) and patient-based (100%/97.6%) evaluation. CONCLUSION: The findings obtained show TSLNA as an effective method for implant placement of adequate length and direction in the atrophic premaxilla providing for success rates comparable to those of implants placed in SA.

Forced surgical extrusion using an axial tooth extraction system as a practicable technique for preserving severely destroyed teeth? - Clinical outcomes up to 4.8 years.

OBJECTIVE: Several extrusion techniques have been described to restore teeth with insufficient coronal tooth structure and to avoid their extraction. Still, there is little evidence for a treatment concept combining surgical extrusion using an atraumatic axial extraction system. MATERIALS AND METHODS: A total of nine patients, each with an iso- or subgingival fractured tooth, were retrospectively examined. Treatment of the damaged tooth comprised an atraumatic forced surgical extrusion performed with an axial tooth extraction system and a more coronal positioning within the socket. The teeth were initially splinted and subsequently restored. The follow-up period was up to 57.1 months and averaged 36.5 (SD: ±13.5) months. RESULTS: All nine teeth were still in situ, without signs of inflammation. During the period of the provisional restoration, six prosthetic complications occurred, which were resolved with little effort, whereas, success rate for the definitive restoration was 100%. No biological complications were observed concerning the root apex or soft tissue. The radiographically measured mean extrusion distance was 3.4 (SD: ±1.0) mm, so that a sufficient prosthetic ferrule could be reestablished. CONCLUSIONS: Surgical extrusions using an axial tooth extraction system demonstrate low biological and prosthetic complications rates over observation time. CLINICAL SIGNIFICANCE: The presented extrusion approach preserves soft and hard tissue and is an efficient treatment option for severely destroyed teeth. Saving hopeless teeth by this relatively predictable and feasible procedure has hardly any disadvantages for patients, and in case of failure, an implant or fixed partial denture are still an option.

Platelet-rich fibrin vs. buccal advancement flap for closure of oroantral communications: a prospective clinical study.

OBJECTIVES: The primary aim was to evaluate the success of the defect closure (tight or open) of oroantral communications (OAC) after treatment with platelet-rich fibrin (PRF) clots or a buccal advancement flap (BAF). Secondary outcome measurements were the evaluation of the wound healing, the displacement of the mucogingival border (MGB), and the pain level. MATERIAL AND METHODS: Fifty eligible patients with an OAC defect larger than 3 mm were randomly assigned to either PRF (test group, n = 25) or BAF (control group, n = 25) for defect closure. In a prospective follow-up program of 21 days, the defect closure healing process, the wound healing course using Landry's wound healing index (score: 0-5), the displacement of the MGB, and the postoperative pain score were evaluated. RESULTS: Five patients in each group were lost to follow-up resulting in 40 patients (20 in each group) for continuous evaluation. On postoperative day 21 (study endpoint), no difference regarding success rate (defined as closure of OAC) was noticed between the test (90%; 18/20) and control group (90%; 18/20). A univariate analysis showed significant differences for age and defect size/height for the use of PRF between successful-tight and open-failed defect healing. At the final evaluation, a significantly (p = 0.005) better wound healing score, a lower displacement of the MGB as well as lower pain-score were seen for the use of PRF. CONCLUSIONS: Based on the findings of the current study, the use of platelet-rich fibrin represents a reliable and successful method for closure of oroantral communications. The use of PRF clots for defect filling is associated with lowered pain levels and less displacement of the mucogingival border. CLINICAL RELEVANCE: The defect size should be taken into account when choosing the number and size of PRF plugs.

Immediately loaded implants simultaneously placed in fresh extraction and healed sites supporting four-implant-supported fixed mandibular prostheses using the all-on-4 concept: A 5-year prospective study.

OBJECTIVES: To evaluate the peri-implant marginal bone level for immediately loaded implants placed simultaneously in both fresh extraction sites (FES) and healed sites (HS) supporting a 4-implant supported mandibular fixed prosthesis (4-ISFMP) using the all-on-4 concept. MATERIAL AND METHODS: A 5-year prospective study was conducted in 24 patients (96 implants) treated with 4-ISFMP including 55 implants inserted in FES and 41 implants in HS. At implant placement (baseline) and at the 1st -, 3rd - and 5th -year follow-up examinations, peri-implant marginal bone level was evaluated radiographically and compared between placement in FES and HS. Marginal bone loss was calculated as the difference in the marginal bone level evaluated at the follow-up periods. Additionally, implant and prosthesis survival rates as well as the presence of peri-implant mucositis (bleeding on probing+[BOP]) and peri-implantitis (BOP+ >2 mm MBL) were evaluated. RESULTS: 22/24 patients with 88/96 implants (dropout rate: 8.3%) were continually followed for 5 years (survival rate: 100%). Radiographically measured marginal bone level differed significantly between FES and HS at implant placement (1.46 ± 0.80 mm vs. 0.60 ± 0.70 mm; p < .001), at the 1-year (-0.04 ± 0.14 mm vs. -0.18 ± 0.20 mm; p = .002) and 3-year (-0.26 ± 0.49 mm vs. -0.58 ± 0.48 mm, p = .049), but not at the 5-year evaluation (-0.90 ± 0.66 mm vs. -1.00 ± 0.59 mm, p = .361). The marginal bone loss differed significantly (p < .001) between FES and HS between implant placement and the 1-year evaluation but not for the 1- to 3-year (p > .99) and the 3- to 5-year period (p = .082). At the 5-year follow-up evaluation, no implant/prosthesis failed (100% survival) and peri-implant mucositis and peri-implantitis were noted in 41.2% and 11.7% at patient level and in 17.6% and 4.5% at implant level respectively. CONCLUSION: Implants placed in FES showed a prolonged peri-implant remodelling process but provided for similar peri-implant marginal bone levels as implants placed in HS at the 5-year evaluation for immediately loaded 4-ISFMP.

The influence of different forms of sinus membrane perforation on the prevalence of postoperative complications in lateral window sinus floor elevation: A retrospective study.

BACKGROUND: Maxillary sinus membrane perforation (SMP) during lateral window sinus floor elevation (SFE) might be associated with postoperative complications (PC). OBJECTIVES: To evaluate the prevalence of PC and clinical implant outcome for different forms of SMP with lateral window SFE. MATERIAL AND METHODS: The prevalence of PC such as maxillary sinusitis, graft necrosis and wound infection was retrospectively evaluated for 434 lateral window SFE (334 patients) with 331 SFE (241 patients) without and 103 SFE (93 patients) with SMP. SMP was additionally classified into four subgroups regarding to membrane perforation size (small-moderate [<10 mm] vs. large [>10 mm]) and membrane biotype ([BT] thin vs. thick). Additionally, patient- and surgery-related risk factors affecting PC and the 1-year implant survival rate were evaluated for SFE without and with SMP and subgroups. RESULTS: A significantly higher prevalence including significant odds ratios of PC such as maxillary sinusitis (10/103 [9.7%] vs. 4/331 [1.2%]; p < 0.021; OR: 8.85; p < 0.021) and graft necrosis (7/103[6.8%] vs. 1/103[0.3%]; p < 0.017; OR:7.43; p < 0.017) was found for SFE with than without SMP. The SMP subgroup with large size and thin BT involved significantly (p < 0.005) more PC (15/20[75%]) than all other SMP subgroups (5/20[25%]). For the risk factors evaluated the univariate analysis demonstrated differences of PC for the presence versus absence of SMP (p < 0.001) and for thin versus thick sinus mucosa (p < 0.038; p < 0.006) but not for sex, smoking, sinus septa and surgical stage. In the multivariate risk factors analysis, PC were significantly related to risk factors such as large size with thin BT (OR:18.049; p < 0.007). The 1-year implant survival rate did not differ between SFE without (99.5%) and with SMP (99.1%), regardless of successfully repaired subtype of SMP. CONCLUSION: The synopsis of perforation size and membrane biotype is crucial in differentiating different forms of SMP assessing and anticipating different prevalences of PC in lateral window SFE.

Prevalence, risk factors, and repair mechanism of different forms of sinus membrane perforations in lateral window sinus lift procedure: A retrospective cohort study.

OBJECTIVES: To evaluate prevalences, affecting risk factors and efforts for repair mechanism for different forms of sinus membrane perforations (SMP) during sinus floor elevation (SFE) using the lateral window technique (LWT). MATERIAL AND METHODS: For 334/434 patients, SFE undergoing LWT prevalence of SMP was retrospectively evaluated including a subselection based on membrane perforation size (<10 mm: small-moderate/≥10 mm: large) and biotype (BT; thick BT/thin BT) into four subgroups (SMP1: thick BT/small-moderate; SMP2: thin BT/small-moderate; SMP3: thick BT/large; SMP4: thin BT/large). For the various subgroups, patient- and surgery-related/anatomic risk factors affecting SMP were evaluated and the scope of sinus membrane repair (SSMR) mechanisms rated with 1 (easy) to 5 (complex) was compared. RESULTS: For 103/434 SMP (27.6%) in 93/334 patients (30.8%) the prevalence of various forms of SMP differed significantly (p < 0.001) among the four subgroups. SMP4 with a prevalence of 45.6% (n = 47) was the most frequent type, while SMP3 had low prevalence with 4.85% (n = 5). Small/moderate SMPs with thick (SMP1: n = 26) or thin BT (SMP2: n = 23) were seen in 26.2% and 23.3%, respectively. Univariate analysis showed significant differences between subgroups with large perforations (SMP3/SMP4) and those with small/moderate perforations (SMP1/SMP2) regarding anatomic risk factors such as residual ridge height (p = 0.023) and history of previous oral surgical interventions (OSI; p = 0.026). Most evidently, multivariate analysis showed that induction of large SMP with thin biotype (SMP4) was significantly affected by the presence of sinus septa (p < 0.022, OR: 2.415), reduced residual ridge height (p < 0.001, OR: 1.842), and previous OSI (p < 0.001, OR: 4.545). SSMR differed significantly (p < 0.001) between SMP4 (4.62 ± 0.49) and the subgroups SMP1 (1.11 ± 0.32), SMP2 (1.08 ± 028), and SMP3 (2.2 ± 0.55). CONCLUSION: The most frequently found type of SMP had characteristics of thin biotype and large size associated with risk factors such as sinus septa, reduced residual ridge, and previous surgical interventions and required challenging repair mechanisms assessing clinical impact.

Influence of butt joint connections with long guiding areas on the stability of single crowns and 3-unit bridges - an in-vitro-study.

Purpose The aim of this study was to evaluate the stability of single crowns and 3-unit bridges in relation to the implant-abutment complex with and without tube in tube connection.Methods 60 specimens with a total of 90 implants (diameter 3.8 mm) were fabricated and distributed into 4 groups: CST (Crown with short tube), CLT (crown with long tube), BNT (Bridge without tube) and BLT (bridge with long tube). All superstructures consisted of one-piece hybrid abutment restorations out of monolithic zirconia, bonded on prefabricated titanium bases and were directly screwed into the implants. Specimen underwent artificial aging (2.000.000 cycles, 120 N, 30° off axis) and were subsequently loaded in an universal testing machine at an angle of 30° until failure. The specimens were examined for damage during and after artificial aging.Results During artificial aging, one test specimen of group CLT and two test specimens of group BNT failed. The average failure load was 498.8 (± 34.4) N for CLT, 418.8 (± 41.5) N for CST, 933.1 (± 26.2) N for BLT and 634.4 (± 29.0) N for BNT, with a statistical differences (p ˂ 0.001) between the crown and bridge groups. All tested samples exhibited macroscopic deformations at the implant shoulder, which were more pronounced in the specimens without a tube in tube connection.Conclusions Single crowns and 3-unit bridges with a long tube in tube connection showed significantly higher fatigue fracture strength compared to restorations with short or without tube in tube connection.

Risk Factor Analysis Affecting Sinus Membrane Perforation During Lateral Window Maxillary Sinus Elevation Surgery.

PURPOSE: To analyze risk factors affecting sinus membrane perforation (SMP) during sinus floor elevation (SFE) procedures using the lateral window technique (LWT). MATERIALS AND METHODS: For patients with SFEs using the LWT, patient-related risk factors (age/sex/smoking/diabetes) and surgical-anatomical-related risk factors (stage approach/sinus side/residual ridge height/sinus membrane thickness/previous surgical interventions) were compared between perforated and nonperforated sites and were evaluated for their influence affecting SMP. Additionally, SMPs were further subdivided into small/moderate (< 10 mm) or large (≥ 10 mm) in dimension, which were also analyzed for risk factors and consecutively for their influence on perforation. RESULTS: The study sample comprised 434 SFE procedures in 355 patients; 94/355 patients (26.5%) presented SMP in 103 of 434 SFE procedures (23.8%). SFE procedures with (n = 103) and without (n = 331) SMP did not differ for patient-related risk factors but differed significantly (P = .001) for surgical-anatomical factors as follows: residual ridge height (3.05 ± 1.35 mm vs 4.15 ± 1.46 mm), sinus membrane thickness (1.2 ± 0.5 mm vs 2.6 ± 1.1 mm), prevalence of staged procedures (78.6% vs 57.7%), presence of maxillary sinus septa (75.7% vs 14.2%), presence of thin (< 1.5 mm) mucosa biotype (62.1% vs 29%), and previous oral surgical interventions (37.9% vs 16.3%). In the multivariate analysis, significant associations of SMP were found with the presence of sinus septa (odds ratio [OR] = 31.992; P = .001), residual ridge height (OR = 1.563; P = .007), sinus membrane thickness (OR = 1.057; P = .001), presence of thin (< 1.5 mm) sinus biotype (OR = 8.883; P = .001), previous surgical interventions (OR = 4.689; P = .002), and smoking habits (OR = 2.238; P = .030). For inducing a large (≥ 10 mm) SMP, the presence of thin sinus membrane thickness/thin sinus membrane biotype (OR = 5.319; P = .006; OR = 22.222; P = .001) and reduced alveolar ridge height (OR = 0.629; P = .026) were assessed as being significant risk factors. CONCLUSION: In general, the presence of sinus septa, thin sinus mucosa, staged procedures, and previous surgical interventions are the main risk factors inducing SMP for SFE using the LWT. In particular, the presence of thin sinus membrane in conjunction with a staged procedure significantly increases the risk for a large SMP.

Mechanical stability of all-ceramic abutments retained with three different screw materials in two-piece zirconia implants-an in vitro study.

OBJECTIVES: To measure the abutment rotation and fracture load of two-piece zirconia implants screwed with three different abutment screw materials. MATERIAL AND METHODS: Thirty-six zirconia implants with 36 zirconia abutments were distributed into 3 test groups: group G connected with gold screws, group T with titanium screws, and group P with peek screws. In the first part of the study, the rotation angle of the abutments was measured. The second part of the study measured the maximum fracture force of adhesively bonded lithium disilicate crowns after artificial aging and fracture modes were reported. RESULTS: In group G, the median rotation angle was 8.0°, in group T 11.6°, and in group P 9.5°. After artificial aging, no screw loosening, crown, abutment, or implant fracture occurred. The median fracture force in group G was 250 N, in group T 263 N, and in group P 196 N. CONCLUSIONS: Rotation angles and fracture loads of two-piece zirconia implants with gold, titanium, or peek screws showed no significant differences; however, fracture loads showed inferior results for group P. CLINICAL RELEVANCE: The indication for the material peek as an abutment screw is still questionable and should be considered carefully.

Use of amniotic membrane for radial forearm free flap donor site coverage: clinical, functional and cosmetic outcomes.

OBJECTIVE: To evaluate the clinical, functional and aesthetic outcomes for radial forearm free flap (RFFF) donor sites covered with amniotic membrane (AM). MATERIAL AND METHODS: The healing process of patients with RFFF donor sites covered with AM was prospectively followed for 1 year. Additionally at the 12-month evaluation, objective scoring systems were used to assess the aesthetic (Vancouver scar scale, VSS: range 1-13) and functional outcome (skin sensibility, hand/wrist functionality [goniometer], grip strength [score 1 = excellent, 5 = poor]). By using a subjective rating system (score 1 = excellent, 5 = poor), the patient-reported aesthetic and functionality outcome was correlated with objective data analysis. RESULTS: Twenty-one out of 23 patients were followed for 12 months (dropout: 2 patients at 3 months). In 17/23 (73.9%) patients RFFF defect covered with AM showed an uneventful healing period (< 3 months). Prolonged healing periods (> 3 months < 6) for 6 patients (26.1%) were attributed to wound infections (4×), seroma (1×) and inflammation (1×). At the 1-year evaluation, there was a significant (p < 0.01) correlation between subjective (2.0 ± 0.71) and objective aesthetic scores (VVS 3.74 ± 2.18), and a successful grip strength (score 1.67 ± 0.86); however, thumb hyposensibility in 76.2% was seen. A high body mass index (BMI) was in conjunction with a negative (p = 0.012) and the use of antihypertensive medications provided positive effects (p = 0.041) on the aesthetic outcome. CONCLUSION: RFFF donor site defects covered using AM show excellent clinical, aesthetic and functional outcome representing patient comorbidities (BMI, antihypertensive drugs) might affect the aesthetic outcome. CLINICAL RELEVANCE: In relation to the excellent outcomes found, the use of AM offers an alternative treatment procedure for RFFF defect covering.

Implant health and factors affecting peri-implant marginal bone alteration for implants placed in staged maxillary sinus augmentation: A 5-year prospective study.

PURPOSE: Evaluating the extent of and the factors affecting marginal bone level (MBL) alterations and consecutively implant success and implant health for implants placed in staged maxillary sinus floor (SF) augmentation. MATERIALS AND METHODS: A 5-year prospective, cohort study was conducted on 85 patients with 124 maxillary sinus augmentation procedure and 295 implants placed. Peri-implant MBL alterations (reductions) were evaluated radiographically at the first year, third year, and fifth year postloading follow-ups and were considered to patient-related risk factors (age, gender, diabetes mellitus, smoking, rheumatic disorders, and history of periodontal disease [PD]), to clinican/surgically related risk factors (membrane perforations, sinus site, and residual ridge height), to implant/prosthesis-related features (implant length, diameter, location, keratinized gingiva, and restoration gap), and to the plaque score. Additionally, implant and prostheses survival/success rate and peri-implant health (mucositis/peri-implantitis) were assessed. RESULTS: About 267/295 implants (drop-out:n9 pat; 28 implants: 9%) were followed for 5 years (survival/success: 99.3%/96.5%), presenting significant (P < .001) differences of MBL alterations (-1.45 ± 0.38 mm) over time. The univariate analysis demonstrated differences of MBL alterations for smokers versus nonsmokers (P = .005), for patients with versus without history of PD (P = .001), and presence versus absence of plaque (P = .041). In the 5-year multivariate analysis, MBL alteration was influenced by time (P = .001) and was related to risk factors as smoking (P = .001; odds ratio [OR] = 6.563) and history of PD (P = .015; OR = 4.450). Significant ORs for MBL alterations were also found for a restoration gap used for a full-arch dentures (P = .001; OR = 8.275) associated with reduced (≤3 mm) residual ridge height (P = .015; OR = 1.365). The overall 5 year incidence of peri-implant mucositis and peri-implantitis was 25.3% and 3.7% at implant level and 30.3% and 6.6% at patient level, respectively. CONCLUSIONS: Apart from the high success rate and healthy status of implant placed in staged SF seen, MBL alteration increased over time and was negatively affected predominately by patient-specific risk factors such as smoking status and previous history of periodontitis.

Implant success and survival rates in daily dental practice: 5-year results of a non-interventional study using CAMLOG SCREW-LINE implants with or without platform-switching abutments.

BACKGROUND: The performance of dental implants in controlled clinical studies is often investigated in homogenous populations. Observational studies are necessary to evaluate the outcome of implant restorations placed in real-life situations, according to standard practice, and to assess the needs of the patients. The aim of this non-interventional study was to reveal the survival, success, and general performance of CAMLOG SCREW-LINE implants and their restorations in daily dental practice. METHODS: Seventeen private practices across five countries participated in this prospective multicenter study. Patients received implants in the maxilla and mandible which were restored either with platform-matching or platform-switching abutments. Patients were followed-up for up to 5 years post-loading. Radiographs and clinical parameters were evaluated and patient satisfaction was evaluated. RESULTS: From a total of 196 patients planned, 185 patients with 271 implants were restored with abutments and fulfilled the follow-up inclusion criteria. Three implant failures were recorded, resulting in a cumulative survival rate of 98.6% after 5 years post-loading. One persistent complication of peri-implantitis occurred. The soft tissue health remained stable, and the papilla height improved after loading. At 5-year follow-up, the mean crestal bone loss was - 0.28 ± 0.60 mm; over 99% of patients reported satisfaction with the restoration as excellent or good. CONCLUSIONS: Implants placed and restored with both platform-matching and platform-switching abutments in daily dental private practice achieved excellent clinical outcomes with highly satisfied patients after 5 years of function, confirming the results obtained in well-controlled clinical trials.

Clinical Outcome of Implants Placed in Staged Maxillary Sinus Augmentation Using Bovine Bone Mineral Mixed with Autogenous Bone at Three Different Ratios: A 5-Year Prospective Follow-up Study.

PURPOSE: To evaluate the 5-year clinical outcomes for implants placed in a staged sinus floor elevation (SFE) procedure and to compare three patient groups with sinus grafts with three different ratios of bovine bone mineral (BBM) and autogenous bone (AB) mixture. MATERIALS AND METHODS: A 5-year prospective cohort study was conducted on 81 patients with 119 staged SFEs non-randomly distributed to three groups based on the origin of the AB and the mixture ratio with BBM: group 1 (locally harvested AB [LHB] from osteotomy sites + BBM, ratio: 1:10), 31 patients, 37 SFEs; group 2: (LHB + intraorally harvested peripheral AB [IHPB] from retromolar/chin region + BBM, ratio: 1:4), 22 patients, 29 SFEs; and group 3 (LHB + extraorally harvested peripheral AB [EHPB] from iliac crest/tibia + BBM, ratio 1:1), 28 patients, 53 SFEs. After graft healing (5 to 7 months), 284 dental implants (group 1: 76, group 2: 61, group 3: 147 [overall: 2.3 implants/sinus]) were placed. After an additional healing period (5 to 7 months), all implants placed were functionally loaded and prospectively followed by clinical and radiographic evaluations assessing implant survival/success rate as well as peri-implant marginal bone level (MBL) alteration at 1, 3, and 5 years postloading. RESULTS: A total of 76/81 patients with 267/284 implants were followed for up to 5 years (dropouts: 5 patients/15 implants; implant loss = 2). The 5-year implant survival and implant success rate (group 1: 100%/98.6%; group 2: 98.3%/96.6%; group 3: 99.3%/95.7%) did not differ between the three graft mixture groups. The peri-implant marginal bone alteration (reduction) averaged over all 5 years was 1.40 ± 0.29 mm for group 1, 1.41 ± 0.22 mm for group 2, and 1.46 ± 0.46 mm for group 3 (P = .187). However, over time, a continual and significant MBL reduction (P = .045) was noted for all groups presenting peri-implant MBL changes between 1 year and 5 years of -0.17 mm (group 1), -0.12 mm (group 2), and -0.24 mm (group 3), respectively. CONCLUSION: According to the clinical results obtained, dental implants inserted in grafted (staged) SFE using a mixture of BBM with a minimal amount of AB harvested from local sites provide for similarly high 5-year implant/augmentation success rates as graft mixtures with AB harvested from peripheral intraoral or extraoral donor sites, confirming no need for additional bone harvesting.

Accuracy and reproducibility of four cone beam computed tomography devices using 3D implant-planning software.

OBJECTIVE: To measure the deviations of four different cone beam computed tomography (CBCT) devices in three dimensions by means of a three-dimensional (3D) implant-planning program. MATERIALS AND METHODS: A master radiographic template with two vertical, two transverse, and two sagittal radiopaque markers was fabricated for a human dry skull. The lengths of the markers were measured with a high-precision caliper. The skull and the template were scanned in each of the four CBCT devices (1. Gendex GXCB-500; 2. Sirona Galileos Comfort; 3. Sirona Orthophos XG 3D; 4. Carestream CS 9300) 19 times (10 scans without moving the skull, and 9 scans with repeated repositioning of the skull in the device, according to the manufacturers' instructions). A 3D implant-planning program was used to measure the lengths of the six markers digitally. Actual and digital measurements were compared to determine device-specific errors. The repositioning of the skull examined the reproducibility of the CBCT devices. Linear measurements were analyzed statistically (P < 0.05). RESULTS: Mean deviations without moving the skull (vertical/sagittal/transverse) for device 1 were 0.023 mm/0.000 mm/0.025 mm (0.07%/0.19%/0.24%), for device 2 were 0.410 mm/0.115 mm/0.080 mm (-1.75%/0.32%/0.88%), for device 3 were -0.665 mm/-0.215 mm/-0.675 mm (-2.71%/-1.82%/-4.42%), and for device 4 were -0.045 mm/-0.135 mm/-0.410 mm (-0.45%/-1.54%/-2.57%). The overall mean deviation for device 1 was 0.028 mm (0.16%), for device 2 was 0.072 mm (-0.95%), for device 3 was 0.518 mm (-2.97%), and for device 4 was -0.197 mm (-1.53%). The mean deviation after repositioning for device 1 was 0.004 mm (-0.65%), for device 2 was -0.250 mm (0.95%), for device 3 was 0.496 mm (-2.66%), and for device 4 was -0.265 mm (-1.92%). Thus, apart from device 3, the deviations increased. CONCLUSION: Deviations from the actual measurements were detected with each device. Therefore, respecting safety distances when placing implants is crucial.

Accuracy and mechanical performance of passivated and conventional fabricated 3-unit fixed dental prosthesis on multi-unit abutments.

PURPOSE: The aim of this study was to evaluate the fit and mechanical stability of conventional versus passive fitting 3-unit fixed dental prosthesis (FDP) screw-retained on implants. METHODS: Twenty acrylic models, each with two embedded implants, were fabricated and functioned as patient-models. Impressions were taken and 20 all-ceramic FDPs were pre-fabricated on the plaster casts. Respectively 10 FDPs were fixed on the plaster casts (group 1) and on the patient-models for passive fitting (group 2). The fit of each FDP was checked on the patient-model by means of visual control (grades 1-10) and microscopic examination. Furthermore, specimens were artificially aged for possible prosthodontic failures, followed by a fracture strength test. RESULTS: Group 2 [1.4 (±0.3)] showed significantly (p<0.001) better results in the visual examination of the marginal fit compared to group 1 [6.3 (±2.4)]. The microscopic marginal misfit was 160µm (±80µm) at the abutment margin and 150µm (±80µm) at the axial wall of the abutment for group 1, respectively, 0µm and 0µm up to 17µm for group 2 (p<0.001). No failure of the FDPs could be observed during artificial aging in both groups. The fracture load showed no significant difference (p=0.60) between group 1 [2583N (±664N)] and group 2 [2465N (±238N)]. CONCLUSIONS: Visual and microscopic examination detected huge differences in marginal fit between groups 1 and 2. However, no statistically verifiable differences could be detected in long-term stability of implant-supported FDPs irrespective of the fit.

Precise Placement of Single-Retainer Resin-Bonded Fixed Dental Prostheses with an Innovative Splint Design.

Single-retainer resin-bonded fixed dental prostheses (RBFDPs) are difficult to position due to the pressure of soft tissue at the pontic area and the single-retainer design. This clinical report describes an innovative technique for the insertion of single-retainer RBFDPs. An incisal inserting splint is used to position the RBFDPs reliably. With the help of grooves in the buccal and incisal area of the splint, the precise positioning of the splint on the adjacent teeth and the RBFDP can be controlled. Also, a hole in the retainer wing region of the splint gives access for pressure application on the wing during the bonding process. With the aid of this method, 25 single-retainer FBFDPs were inserted in the correct position in a case series. The splint described here allows the precise insertion of single-retainer RBFDPs and simplifies delivery.

Mandibular Full-Arch Fixed Prostheses Supported on 4 Implants with Either Axial Or Tilted Distal Implants: A 3-Year Prospective Study.

PURPOSE: This prospective study evaluated the clinical and radiographic outcome of distally cantilevered 4-implant-supported fixed mandibular prostheses (4-ISFMP) with distal implants either in axial or distally tilted direction. MATERIAL AND METHODS: Forty-one mandibulary edentulous patients received acrylic veneered 4-ISFMP with casted framework. Based on distal implant placement direction patients were assigned to 2 groups: 21 patients with four (2 anterior/2 posterior) axial implants (axial-group I) and 20 patients with 2 anterior axial/2 distal tilted implants (tilted-group II). Patients were prospectively followed for 3 years by annual examinations of implants and prosthetic survival rates including assessment for biological and mechanical complications. Additionally, peri-implant marginal bone resorption [MBR], pocket depth [PD], plaque index [PI], bleeding index [BI] and gingival index [GI], and calculus index [CI] were evaluated at each annual follow-up. RESULTS: 37/41 patients (19 axial-group I, 18 tilted-group II) and 148/164 implants were followed at the 1-, 2-, and 3-year evaluation (dropout rate: 11.8%) presenting no implant and denture loss (100% survival). The overall, MBR at year 1, 2, and 3 was 1.11 ± 0.4 mm, 1.26 ± 0.42 mm, and 1.40 ± 0.41 mm, respectively, representing a significant (p < .001) continuing time depending annual reduction. MBR and PD did not differ between anterior and posterior regions in both groups or for anterior and posterior regions between the groups. PI and CI were significantly (p < .001) higher for implants in anterior regions than for posterior regions in both groups. Moreover, posterior implant regions showed significantly (p < .001) higher PI and CI for axial-group I than for tilted-group II over time. Biological and mechanical complications as well as GI and BI did not differ between the groups over a 3-year follow-up period. CONCLUSION: For clinical implant and prosthesis outcome no statistical significant mean differences were noted for distally cantilevered 4-ISFMP supported by distal implants placed in tilted or axial direction.