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Eur J Ophthalmol ; 31(2): NP119-NP122, 2021 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-31390886

RESUMEN

PURPOSE: To report three cases of juvenile myasthenia gravis aged between 18 and 24 months with ocular symptoms as their first presentation. METHOD: A case series. RESULTS: We present a case series of juvenile myasthenia gravis in a tertiary centre in Malaysia. Two of the three cases consist of a pair of twins who presented with ptosis of bilateral eyes; the first twin presented 4 months later than the second twin. These two cases were positive for anti-acetylcholine receptor antibodies and had generalized myasthenia gravis, whereas the other case was negative for receptor antibodies and was purely ocular myasthenia gravis. CONCLUSION: Juvenile myasthenia gravis is relatively rare in toddlers. Early diagnosis and commencement of treatment is important to slow the progression of the disease and avoiding life-threatening events.


Asunto(s)
Blefaroptosis/diagnóstico , Enfermedades en Gemelos/diagnóstico , Miastenia Gravis/diagnóstico , Gemelos Monocigóticos , Autoanticuerpos/sangre , Blefaroptosis/tratamiento farmacológico , Blefaroptosis/genética , Preescolar , Inhibidores de la Colinesterasa/uso terapéutico , Enfermedades en Gemelos/tratamiento farmacológico , Enfermedades en Gemelos/genética , Quimioterapia Combinada , Femenino , Glucocorticoides/uso terapéutico , Humanos , Lactante , Miastenia Gravis/tratamiento farmacológico , Miastenia Gravis/genética , Prednisolona/uso terapéutico , Bromuro de Piridostigmina/uso terapéutico , Receptores Colinérgicos/inmunología
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