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J Microbiol Immunol Infect ; 52(2): 312-319, 2019 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-30472096

RESUMEN

BACKGROUND: Genitourinary tuberculosis (GUTB) is rare but fatal if not diagnosed early. The purpose of this study was to investigate the outcomes of GUTB in Taiwan. METHODS: We retrospectively reviewed medical records of 57 patients who were diagnosed as GUTB from January 2002 to December 2016, over a 15-year period. Demographic data and clinical manifestations were recorded for analysis. RESULTS: There were 37 males and 20 females with a median age of 71 years. Kidney (24.6%) was the most involved organ. Fever (56.1%) was the major presentation. Sixteen (28.1%) patients presented unfavorable outcome. Compared with the favorable outcome group, the unfavorable outcome group had more malignancy (p = 0.013), fever (p = 0.020), anemia (p = 0007), thrombocytopenia (p = 0.003), and hypoalbuminemia (p = 0.015). In a multivariate analysis, fever (odds ratio: 42.716, 95% confidence interval: 1.032-1767.569; p = 0.048) was identified as prognostic factors for unfavorable outcome. CONCLUSION: GUTB is often in advanced stages with a high mortality in Taiwan. Establishing a diagnosis is difficult and requires thorough investigation. Fever is associated with unfavorable outcome.


Asunto(s)
Hospitales de Enseñanza , Tuberculosis Urogenital/tratamiento farmacológico , Tuberculosis Urogenital/epidemiología , Tuberculosis Urogenital/patología , Tuberculosis Urogenital/fisiopatología , Adulto , Anciano , Anciano de 80 o más Años , Anemia/epidemiología , Antituberculosos/farmacología , Antituberculosos/uso terapéutico , Femenino , Fiebre/epidemiología , Humanos , Hipoalbuminemia/epidemiología , Estimación de Kaplan-Meier , Enfermedades Renales/epidemiología , Enfermedades Renales/microbiología , Modelos Logísticos , Masculino , Pruebas de Sensibilidad Microbiana , Persona de Mediana Edad , Mortalidad , Análisis Multivariante , Neoplasias/epidemiología , Neoplasias/microbiología , Oportunidad Relativa , Pronóstico , Estudios Retrospectivos , Factores de Riesgo , Taiwán/epidemiología , Trombocitopenia/epidemiología , Resultado del Tratamiento , Sistema Urinario/cirugía
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