[Modern surgical tactics in Crohn's disease in coloproctological centre of Ukraine].

Surgical tactics in Crohn's disease (CD) was elaborated by the authors, basing, on analysis of modern views on pathogenesis, peculiarities of clinical course, possibility of diagnosis and experience of treatment of the disease. It envisages a modern diagnosis of the disease, prognostication of the recurrence and postoperative complications occurrence, the indications optimization, the choice of surgical treatment method Application of the surgical tactics elaborated for CD in 121 patients have permitted to improve objective estimation of the disease severity, to prognosticate the complications occurrence, to optimize indications for surgical treatment and the choice for method o conditionally radical, restorational, reconstructive--restoration stages of operative intervention, to reduce the disease recurrence rate, postoperative complications and postoperative lethality.

[Modern surgical tactics in Crohn's disease].

Surgical tactics of Crohn's disease (CD) treatment was elaborated on base of modern information analysis, concerning pathogenesis, peculiarities of clinical course, possibilities of diagnosis, experience in the disease treatment. The tactics provides a timely diagnosis of the disease, prognostication for the recurrence occurrence and postoperative complications, the indications and the method of surgery optimization. Application of the elaborated surgical tactics in CD in 121 patients have permitted to improve the objective estimation of the disease severity, to prognosticate complications, to optimize surgical indications, as well as a choice of the method of a conditionally-radical, restorational, reconstructive-restorational stages of operative intervention, to reduce the disease recurrences rate, postoperative complications, postoperative lethality.

[Application of antiseptic decasan in purulent infections of pararectal region].

The results of studying of antiseptic preparation Decasan for the treatment of patients, suffering purulent infections of pararectal region, are adduced. Efficacy of Decasan was analyzed in 102 patients. The results of investigation obtained are trusting hig antiseptic efficacy of preparation, witnessing possibility of its application as a preparation of choice for the treatment of patients, suffering purulent infections of pararectal region.

[Surgical policy in reconstructive surgery on the colon].

Thirty-year experience with 1685 reconstructive operations on the colon is analyzed. Novel surgical policy has increased the rate of primary-reconstructive operations for the last 5 years from 78.8 to 87.9%, decreased the number of postoperative complications from 33 to 21.8%, intestinal anastomosis-dependent complications -- from 22.6 to 8.4%, postoperative lethality -- from 6.9 to 2.4%, raised the rate of good functional results from 64 to 88.2%.

[Compression anastomoses of the large intestine under complicated conditions]. / Kompressionnye tolstokishechnye anastomozy v oslozhnennykh usloviiakh.

Results of the application of apparatus AKA-2 for the formation of compressive anastomoses under complicated conditions are discussed. Among them are: acute and chronic ileus, peritonitis, diabetes mellitus etc. Common negative factors for all the patients were symptoms of secondary immune deficiency and specific endogenous intoxication resulting from chronic internal irradiation by radionuclides (consequences of the disaster in Chernobyl atomic power station in 1986). In 1987-1990 operations were performed on 84 patients. Compressive colonic anastomoses were made with apparatus AKA-2. All the patients lived in Kiev and neighbouring regions from 1986. From the patients operated upon 81% had colorectal cancer localized in left portions of the colon, 19% of the patients had inflammatory diseases of the colon. The application of compressive colonic anastomoses under the complicated conditions proved to be sufficiently reliable in the nearest and late terms of observations.

[T-cell immunodeficiency and the status of the reparative processes in patients with Crohn's disease of the large intestine]. / T-kletochnyi immunodefitsit i sostoianie reparativnykh protsessov u bol'nykh bolezn'iu Krona tolstoi kishki.

Clinico-immunological examination of 35 patients with chronic colostasis at the stage of subcompensation and 10 patients with Crohn's disease of the colon before and after operative treatment (subtotal colectomy) revealed that presence of marked T-cellular immunodeficiency mainly due to helper subpopulation and inversion of helper-suppressor index in patients operated on for Crohn's disease of the colon, inhibiting the reparative processes and weakening anti-infection defense in these patients.

[Subdiaphragmatic vagotomy in acute experimental pancreatitis]. / Poddiafragmal'naia vagotomiia pri ostrom pankreatite v éksperimente.

Subdiaphragmatic vagotomy influences on the course and outcome of acute pancreatitis were studied experimentally in 26 mongrel dogs. Truncal and selective vagotomy was performed in the animals with experimentally induced pancreatitis. Histological and histochemical methods showed that truncal vagotomy produced a positive effect on the course and outcome of experimental pancreatitis.

[Diagnostic possibilities of roentgeno-endoscopic and morphologic methods of examining the colon in nonspecific colitis]. / Diagnosticheskie vozmozhnosti rentgenoéndoskopicheskogo i morfologicheskogo metodov issledovaniia tolstoi kishki pri nespetsificheskikh kolitakh.

The paper is concerned with comparative assessment of the diagnostic potentialities of the x-ray, endoscopic and pathomorphological methods of investigation. The results of the examination of 100 patients operated upon for nonspecific ulcerative colitis (54) and Crohn's disease (46) were analyzed. The advantages of these methods were demonstrated. A conclusion was made of the necessity of the use of the above methods for specified diagnosis of nonspecific colitis.