1.
Eksp Klin Farmakol
; 77(11): 23-6, 2014.
Artículo
en Ruso
| MEDLINE
| ID: mdl-25668944
RESUMEN
We have conducted for the first time an experimental study of pharmacokinetics of dicholine succinate (DCS) for different ways of its administration in rats The quantitative evaluation of DCS and its metabolites was performed by the radioactive isotope technique. Various parameters of DCS pharmacokinetics were estimated, including the dose dependence of drug content in the blood plasma, total bioavailability, distribution kinetics, and the main ways of DCS excretion.