Genetic susceptibility testing for beryllium: worker knowledge, beliefs, and attitudes.

BACKGROUND: We sought to gain insight into workers' knowledge, beliefs, and attitudes on the subject of testing for genetic susceptibility to beryllium. METHODS: Five focus groups were held with 30 current and former beryllium workers and nine family members. Audio recordings were transcribed and assessed by hierarchical coding using an inductive approach. RESULTS: Some workers were unclear about the distinction between genotoxicity and heritability. A key finding is that they perceived the benefits of a positive test result to be related to enhanced autonomous decision-making. The major concern cited by participants was potential abuse of genetic information by employers. Complete financial separation of a prospective testing entity from the employer was seen as crucial. CONCLUSIONS: A window of opportunity exists to create regional partnerships for translational research on genetic susceptibility testing. Such partnerships would involve labor, management, public health scientists, primary care professionals, and other stakeholders. They would be critical to identifying testing strategies that maximize worker autonomy along with the public health advantages of genetic testing.

Ankle brachial index measurement in primary care setting: how long does it take?

BACKGROUND: Peripheral arterial disease (PAD) affects over 8 million people in the United States and has been found to be associated with an increased incidence of coronary and carotid artery disease. The ankle brachial index (ABI) measurement is a highly specific noninvasive screening and diagnostic test for PAD, but is rarely performed in primary care office settings. This study sought to determine the actual performance time involved in completing an ABI in a primary care office. METHODS: Data were collected by one provider on a convenience sample of women who met the inclusion criteria. The time was recorded at the beginning and upon the completion of the ABI procedure for each patient. Analysis of the time data was completed and barriers to performing the ABI were recorded by the provider. RESULTS: The average time to complete an ABI was 5 minutes, with a range of 3-11 minutes. In 83.8% of patient encounters, the ABI procedure took less than 6 minutes to complete. Barriers identified by the provider included the additional time needed to explain the test and assist patients into the proper testing position. CONCLUSIONS: The actual performance time for an ABI in a primary care setting takes an average of 5 minutes, but additional time may be required for patient preparation and education. With proper scheduling and training, the ABI can be completed in a timely manner. The ABI is an important screening/diagnostic test that can be performed in primary care and potentially impact patient treatment plans.

Enhancing research in a family medicine program: one institution's story.

BACKGROUND AND OBJECTIVES: To enhance research productivity among East Tennessee State University's faculty, the Department of Family Medicine developed and implemented a multi-component initiative to expand multidisciplinary primary care research. METHODS: The research support infrastructure expanded to include a family physician research director, three PhD faculty researchers, two research assistants, a statistician, and a grant/science writer. A monthly seminar series, quarterly workshops, and a formal mentoring program paired more-experienced with less-experienced faculty researchers. Through a competitive mechanism in which junior faculty submitted proposals, a multidisciplinary committee selected two family physician researchers to receive protected time to develop their research. RESULTS: From 2001-2006, more than 25 experienced researchers served as mentors, lecturers, consultants, or reviewers. Fifteen mentor-mentee pairs were formed. Of 30 family medicine faculty, the number actively engaged in research, including project design, data collection, oral presentation of results, or journal article submissions, increased from seven (23%) to 19 (63%). From 2001-2006 the number of presentations at professional meetings increased, and articles in peer-reviewed journals increased nearly fivefold. Grant submissions increased, with 19 faculty members participating in grant-writing teams. Based on the success of this initiative, the program has expanded to include faculty members in general internal medicine and general pediatrics. CONCLUSIONS: Our multi-component initiative successfully builds and sustains a primary care research program.

Medication, allergy, and adverse drug event discrepancies in ambulatory care.

BACKGROUND AND OBJECTIVES: A first step in reducing medication errors is for health care workers to be aware of a patient's medications, allergies, and any previously documented adverse drug events (ADEs). This study sought to determine the frequency of medication and allergy/ADE-related discrepancies in a family medicine residency clinic. METHODS: Patients were contacted prior to appointments and asked to bring in prescription and over-the-counter medications. A research assistant interviewed 157 patients and recorded each drug a patient was taking, together with dosage, dosing frequency, known allergies, and demographic information. This information was then compared to similar information in the medical record. RESULTS: Overall, 97% of patients had at least one discrepancy between medications listed in the medical record and medications they were taking, and 32% had an allergy/ADE discrepancy. Discrepancies were highest for women, those with cardiovascular disease, and those hospitalized within the last year. Only the total number of medications was predictive of a discrepancy, however, accounting for 25% of the variability. CONCLUSIONS: A higher medication discrepancy rate existed in this family medicine residency clinic than the 26%--76% rate that is documented in the literature. The results point to a need for better medication, allergy, and ADE awareness.