[Methodological approaches to the morphological assessment of the skin under slight toxic effects]. / Metodicheskie podkhody k morfologicheskoi otsenke kozhi v usloviiakh slabogo toksicheskogo vozdeistviia.

One-fold treatment of rat skin with 3% water solution of potassium bichromate resulted in slight toxic effects in epidermocytes, sebaceous gland cells and epithelial follicles. System of indexes for the slight toxic effects to assess was worked up.

[Hygienic evaluation of mineralizing lime substances for correction of mineral composition of low-mineral drinking water]. / Gigienicheskaia otsenka mineralizuiushchikh materialov--izvestniakov dlia korrektsii solevogo sostava malomineralizovannoi pit'evoi vody.

4 out of 6 mineralizing lime materials that were studied have been recommended for the practical application with the aim to correct the mineral composition of drinking low-mineralized water. The possibility to predict the biological properties of multicomponent mineralizing materials has been established on the basis of results of analysis of their chemical composition.

[Protective and adaptive reactions of the air-conducting and respiratory portions of the lungs to exposure to atmospheric pollutants]. / Zashchitno-prisposobitel'nye reaktsii vozdukhonosnykh i respiratornykh otdelo legkikh pri vozdeistvii zagriaznitelei atmosfernogo vozdukha.

A complex structural-functional investigation of protective-adaptive reactions of various parts in the lungs has been performed under inhalation of some toxic substances. To a continuous inhalation effect of 1,2-dichlorpropane, 132 non-inbred white rats have been subjected. At the first stage of the investigation, using specific loading tests, periods for formation of increased and decreased resistivity of the experimental animals have been defined. Under the given scheme of the experiment the state of a maximal resistivity develops by the 30th day of the influence, then it gradually decreases and in 60 days becomes significantly lower than in the control animals. Synchronous changes in resistivity and in loading of the respiratory organs are revealed. The structural-functional investigation of the pneumatic and respiratory parts of the lungs during the period of formation (in 5 days of the influence), at maximum (in 30 days of the influence) and at decreased resistivity (in 60 days of the influence) makes it possible to establish that functional activity of the aero-hematic, aero-epithelial barriers and the surfactant system of the lungs increases during the period of elevated resistivity and decreases at the stage of reduced endurance to the loading. A suggestion is made that, together with other factors, increasing functional activity in the systems studied is an essential component for formation of the elevated stability of the organism against toxic inhalation.

[The ultrastructure of the white rat olfactory epithelium]. / Ul'trastruktura oboniatel'nogo épiteliia beloi krysy

As a result of electron microscope observation of olfactory mucosa in the white rat, variability of structure of the supporting cells was established. Among these cells secretory ones and those rich in endoplasmic reticulum were discovered. The differences revealed in dendrites and rods of olfactory cells seem to be associated with functional condition of these cells.