1.
Scand J Rheumatol
; 52(6): 703-704, 2023 11.
Artículo
en Inglés
| MEDLINE
| ID: mdl-37376955
Asunto(s)
Artritis Reumatoide , Leucemia Linfocítica Crónica de Células B , Humanos , Artritis Reumatoide/complicaciones , Artritis Reumatoide/tratamiento farmacológico , Leucemia Linfocítica Crónica de Células B/complicaciones , Leucemia Linfocítica Crónica de Células B/tratamiento farmacológico , Pirimidinas/uso terapéutico
2.
Int J Lab Hematol
; 29(3): 215-20, 2007 Jun.
Artículo
en Inglés
| MEDLINE
| ID: mdl-17474900
RESUMEN
Multiple myeloma (MM) is a malignant plasma cell disorder that involves multiple genetic abnormalities. Chimeric transcription factors, created by gene fusion as a result of chromosomal translocations, have been implicated in the pathogenesis of the disease. Here, we report the conventional cytogenetic analysis of a MM patient that showed a complex set of novel chromosomal rearrangements, including t(13;16)(q14;q24) and t(1;15)(q10;q26). This is probably the result of fusion of previously known genes, and would contribute to prognostic significance of the disease.