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Virus Genes ; 42(1): 71-5, 2011 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-21053063

RESUMEN

We sequenced the genome of LATC06 generated by in vitro passage in Vero cells of the lapinized-avianized (LA) strain and compared its sequence to those of other rinderpest viruses. The LATC06 genome consists of 15882 nucleotides. Its transcriptional regulatory control sequences (TRSs) at gene boundaries are identical to those of the Kabete O strain. Cleavage sites for generating F1/F2 proteins were identified in the same amino acid position (aa 108) as F proteins in LATC06, L13, RBT1, Kabete O, and RBOK strains. There are three predicted N-glycosylation sites of H proteins in LA (Japan) and LATC06 strains. The six epitopes of H protein in the LA (Japan) strain that elicit immunodominant humoral responses are also found in the LATC06 strain.


Asunto(s)
Genoma Viral , Virus de la Peste Bovina/genética , Animales , Chlorocebus aethiops , Epítopos/genética , Glicoproteínas/genética , Hemaglutininas Virales/genética , Proteínas de la Membrana , Proteínas de la Nucleocápside/genética , Filogenia , Proteína Disulfuro Isomerasas , ARN Viral/genética , Peste Bovina/virología , Análisis de Secuencia de ARN , Homología de Secuencia de Aminoácido , Células Vero , Proteínas Virales de Fusión/genética
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