RESUMEN
OBJECTIVE: To explore the status of depression in patients with advanced schistosomiasis and its influencing factors, so as to provide the evidence for improving psychological interventions. METHODS: A total of 206 patients with advanced schistosomiasis were investigated with the self-designed general information questionnaire, the Self-Rating Depression Scale, and WHOQOL-BREF Form. RESULTS: Among the 206 cases, the incidence of depression was 69.4%, and depression was negatively related to the quality of life (P = 0.000). The multiple logistic regression analysis showed that the times of hospitalization (ß = 0.442, P = 0.007) was a risk factor for depression, while the high education levels (ß = -0.583, P = 0.011) and the history of portal hypertension operation (ß = -0.917, P = 0.000) were the protective factors. CONCLUSION: The incidence of depression in advanced schistosomiasis patients is high, and it is influenced by various factors. Therefore, we should take corresponding interventions to reduce its occurrence.