1.
Angew Chem Int Ed Engl
; 59(31): 12714-12719, 2020 Jul 27.
Artículo
en Inglés
| MEDLINE
| ID: mdl-32281220
RESUMEN
A highly effective C-O coupling reaction of (hetero)aryl electrophiles with primary and secondary alcohols is reported. Catalyzed by a NiII -aryl complex under long-wave UV (390-395â nm) irradiation in the presence of a soluble amine base without any additional photosensitizer, the reaction enables the etherification of aryl bromides and aryl chlorides as well as sulfonates with a wide range of primary and secondary aliphatic alcohols, affording synthetically important ethers. Intramolecular C-O coupling is also possible. The reaction appears to proceed via a NiI -NiIII catalytic cycle.