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Int J Legal Med ; 129(3): 463-4, 2015 May.
Artículo en Inglés | MEDLINE | ID: mdl-25217341

RESUMEN

Allele frequencies and forensic parameters for 15 autosomal loci included in the AmpFlSTR® Identifiler kit were estimated in a sample of 57 unrelated Afro-descendants from Nor Yungas (Bolivia). Buccal swabs samples were obtained from voluntary donors, after consent was given. All loci were in Hardy-Weinberg equilibrium after Bonferroni correction. D21S11 was the most informative locus, while the least discriminating locus was D3S1358. The combined power of discrimination and the combined probability of exclusion were >0.99999999 and >0.99997, respectively. The multidimensional scaling (MDS) plot generated by Rst matrix supported that Afro-Bolivians of Nor Yungas preserved a stronger African descent compared to other admixed Latin American populations. These results amplified the Bolivian databases of autosomal STR loci and may provide a useful tool for human identification tests and population genetic studies.


Asunto(s)
Población Negra/genética , Cromosomas Humanos/genética , Dermatoglifia del ADN/métodos , Etnicidad/genética , Frecuencia de los Genes/genética , Genética de Población , Repeticiones de Microsatélite/genética , Bolivia , Femenino , Genética Forense , Tamización de Portadores Genéticos , Sitios Genéticos , Humanos , Masculino , Linaje
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