Of These, Faith, Hope, and Love: Assessing and Providing for the Psychosocial and Spiritual Needs of Burn Patients.

Burn treatment has grown increasingly advanced and technologically capable. Clinicians must take into account, however, multidimensional patient needs that factor into long-term burn recovery. Important psychosocial factors associated with burn care include psychiatric comorbidities, such as anxiety and depression, healthy family relationships, social support, and community involvement. Spiritual factors and resources, such as time spent praying and/or meditating and access to pastoral services, are also important to consider. Further study is needed to identify specific psychosocial and spiritual needs of patients and to develop interventions or therapies that specifically provide for these needs.

Pressure ulcers and perineal reconstruction.

LEARNING OBJECTIVES: After reading this article, the participant should be able to: 1. Discuss the approach and rationale of pressure sore management, including specific techniques of bone biopsy and postoperative care resulting in a significant reduction in recurrence rates. 2. Develop a surgical plan for reconstructing defects of the perineum, taking into account the local tissue factors and the soft-tissue requirements for reconstruction. SUMMARY: As close as the buttocks and the perineum are anatomically, the clinical settings and the solutions to wound problems in these areas are quite different. The ubiquitous "pressure ulcer" presents more commonly as a clinical management problem than a reconstruction issue. On the other hand, the perineal defect is almost always a reconstruction challenge following tumor ablation. For these reasons, the authors have chosen to separate this Continuing Medical Education offering into two parts. The first part addresses the pressure ulcer, while the latter discusses the perineum.

Vastus lateralis flap reconstruction after girdlestone arthroplasty: thirteen consecutive cases and outcomes.

BACKGROUND: Pressure ulcers are found in approximately 4.7% of hospitalized populations. Up to 12.3% of hospitalized populations are at risk for developing these wounds. Decubitus ulcers are more common among the inpatient spinal cord injury group, with prevalence rates up to 30%. Surgical intervention is required when bone or the hip joint becomes involved. Girdlestone arthroplasty is a procedure that excises affected proximal femur and acetabular tissues; however, this resection typically results in a sizeable defect. The vastus lateralis flap has been extensively reviewed as a soft tissue filler option for this deficit. MATERIALS AND METHODS: Thirteen consecutive cases from a single institution using the vastus lateralis muscle flap reconstruction after Girdlestone arthroplasty were reviewed. A search of internal records identified 11 patients with 13 vastus lateralis flap reconstructions performed immediately after Girdlestone arthroplasty for stage 4 ulcers or chronic, infected wounds affecting the hip joint. All patients involved were subjected to a similar standardized post-procedure activity schedule. Complications were defined as minor (superficial wound breakdown) or major (requiring further operative procedures to close the wound). RESULTS: The majority of patients were male (91%) with a mean age of 43 years at the time of the procedure. All wounds involved the hip joint proper. Ninety-one percent of the patients had a history of spinal cord deficits. Thirty-one percent of the flaps had minor, superficial wound breakdown. Another 31% of the reconstructions required an additional operative procedure for major wound complications. One patient's wound was from multiple prior failed hip replacements. He eventually became ambulatory using a walker after reconstruction. Ultimately, 69% of the flaps healed satisfactorily without the need for further operative intervention. CONCLUSIONS: Surgical debridement is required for chronic wounds involving the proximal femur, acetabulum, and hip joint. This review demonstrates that the use of a single-stage procedure including Girdlestone arthroplasty with immediate vastus lateralis muscle flap reconstruction is a practical treatment option for chronic wounds involving the acetabular joint. The use of a postoperative protocol and subsequent sitting schedule contributed to the success of these reconstructions. Overall, this procedure is applicable to spinal cord injury/pathology patients and to failed total hip arthroplasty patients for future assisted ambulation.

Does systemic isotretinoin inhibit healing in a porcine wound model?

BACKGROUND: Within the plastic surgery community, it is widely believed that waiting a minimum of 6 to 12 months after patient cessation of systemic retinoid therapy is necessary before proceeding with elective surgery. OBJECTIVE: The authors investigate partial- and full-thickness wound healing after treatment with systemic isotretinoin in a porcine model. METHODS: Following institutional approval, 2 Hanford miniature pigs were obtained. One pig received isotretinoin at a dose of 2 mg/kg/d, administered orally along with pig feed over a 60-day period; the other (control) pig received only pig feed over the same time period. After the treatment period ended, a total of 24 full-thickness wounds and 24 partial-thickness wounds were made on each pig. The wounds were evaluated by photographic and histological analysis at 7, 14, and 28 days. RESULTS: The average full-thickness wound size in the control animal was 0.4346 cm(2) at 14 days and 0.0689 cm(2) at 28 days. The average full-thickness wound size in the isotretinoin-treated animal was 0.4685 cm(2) at 14 days and 0.0363 cm(2) at 28 days. The differences were not statistically significant between the 2 animals at either time point. On histological analysis, the healing characteristics of partial- and full-thickness wounds were similar at 7, 14, and 28 days for both animals. CONCLUSIONS: Invasive surgery might be safely performed even in the presence of recent isotretinoin therapy. This finding challenges the current practice of waiting longer than 6 months after completion of therapy to perform surgery.

Protocol management of late-stage pressure ulcers: a 5-year retrospective study of 101 consecutive patients with 179 ulcers.

BACKGROUND: Despite a 12 to 82 percent pressure ulcer recurrence rate, no standard protocol exists for postoperative management. The authors reviewed a single surgeon's experience using a standard protocol: surgery and immediate reconstruction regardless of nutrition, intraoperative bone culture guiding postoperative antibiotic use, and hospital admission for 3 weeks of flat bedrest before graduated sitting. METHODS: A 5-year retrospective chart review was performed on consecutive surgically treated pressure ulcers. A search of billing records identified 101 patients with 179 ulcers. Data abstracted included demographics, comorbidities, location and stage of ulcers, treatment history with outcomes, and laboratory data. RESULTS: Seventy-nine percent of the patients were men with a mean age of 49.4 years. Of 179 ulcers, 49.7 percent were ischial, 26.8 percent were sacral, and 19 percent were trochanteric; 87.7 percent of ulcers were stage 4. Primary closure was performed on 45.8 percent; others underwent flap closure. There was no correlation between positive bone cultures and recurrence or complications. The overall recurrence rate was 16.8 percent at a mean period of 435.9 days. New ulcer occurrence was 14.5 percent and the complication rate was 17.3 percent. Admission prealbumin and albumin did not correlate with recurrence or complication. Mean follow-up was 629 days. CONCLUSIONS: A standard clinical pathway for pressure ulcer treatment improves long-term outcomes; the authors' protocol's validity is supported by low recurrence and complication rates. Nutritional data do not predict outcome. Intraoperative bone cultures are the most valid method of diagnosing osteomyelitis; results should not delay definitive treatment. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.

Definitive diagnosis and management of axillary hyperhidrosis: the VapoMeter and suction-assisted arthroscopic shaving.

BACKGROUND: Axillary hyperhidrosis is a benign, yet significant, disability that not only impairs social interaction but also affects occupational activities. OBJECTIVES: The author provides a detailed description of axillary shaving, a procedure with proven results. He also describes the use of the VapoMeter (Delfin Technologies, Stamford, Connecticut), which accurately and easily measures sweating in g/m(2)/h. METHODS: Although a total of 45 patients have received this surgery since 2005, this report includes only the last eight patients (16 axilla) for whom both pre- and postoperative VapoMeter readings are available. RESULTS: The average preoperative VapoMeter reading was 473 g/m(2)/h (range, 98-998), which improved to an average of 58 g/m(2)/h postoperatively (range, 21-227). As a comparison, controls for all axilla had an average measurement of 23.7 g/m(2)/h (range, 18-31). CONCLUSIONS: When combined with the effective surgical technique of axillary shaving, the VapoMeter provides an objective measure to both definitively diagnose and confirm results of the shaving. With this protocol, patients who require surgical intervention for their hyperhidrosis can be reassured that the procedure is indeed effective in improving their condition.

Is there a simple, definitive, and cost-effective way to diagnose osteomyelitis in the pressure ulcer patient?

BACKGROUND: Despite advances in managing pressure ulcers, there is still no definitive way to diagnose bone infection (osteomyelitis) short of open biopsy. An effective, less invasive diagnostic method might result in cost savings and improved care; however, needle aspiration, computed tomography scan, magnetic resonance imaging, ultrasound, and bone scans have proven unsatisfactory in predicting osteomyelitis. The authors reviewed preoperative radiologic studies of stage IV pressure ulcer patients and their bone biopsy results to determine which radiologic studies are most diagnostic for osteomyelitis. METHODS: Patients (n = 44) having surgical débridement of stage IV ulcers with open bone biopsy after prior radiographic imaging (plain films, ultrasound, computed tomography, magnetic resonance imaging, and/or nuclear bone scans) were included. Studies were interpreted by a single musculoskeletal radiologist blinded to information from the medical record and following standard radiologic criteria for the diagnosis of osteomyelitis. RESULTS: The percentage of patients with biopsy-proven osteomyelitis identified with imaging was 50 percent using a computed tomography scan and 88 percent using a plain film of the bony area of involvement. The overall sensitivity of either radiologic study was 61 percent. The percentage of patients without osteomyelitis identified as not having the condition by imaging was 85 percent for the computed tomography scan and 32 percent for the plain film. Overall specificity of both studies was 69 percent. CONCLUSION: Preoperative radiologic studies for osteomyelitis in a pressure ulcer are far from definitive; however, if a radiologic study is used to make that diagnosis in a stage IV pressure ulcer, it would appear that a plain film would suffice.

Is oncologic safety compatible with a predictably viable mastectomy skin flap?

BACKGROUND: Necrosis with partial loss of mastectomy flaps is an all-too-common complication of otherwise advantageous skin-sparing mastectomies. Central to the problem of predictable flap viability is the thickness of the skin flaps. Seeking a balance between the preservation of adequate flap thickness and maintenance of oncologic principles, the authors sought guidelines to help the oncologic surgeon identify the non-breast-bearing subcutaneous layer of tissue between the epithelial/dermal tissue of the breast and its parenchyma. METHODS: Breast specimens of women receiving reduction mammaplasty were prospectively examined by an experienced, blinded breast pathologist. Subcutaneous tissue thickness was measured from caudal dermis to breast parenchyma and correlated with age, body mass index, and breast specimen weight. RESULTS: No significant correlation was found between body mass index, age, or breast sample weight and the thickness of the subcutaneous tissue. Measurements did reveal a consistent and distinct layer of non-breast-bearing subcutaneous tissue between the dermis and the breast parenchyma, with a median thickness of about 1 cm. CONCLUSION: Both oncologic safety and a viable skin flap can be achieved if the subcutaneous layer present in most breasts is used as a guide for elevating the skin flaps, with subsequent oncologically safe resection of the cancer-containing breast parenchyma.

Head and neck melanoma.

Nearly 20% of malignant melanoma in the human body occurs in the head and neck. Most studies divide the sites of origin of malignant melanoma in the head and neck into the following areas: the face, the scalp and neck, the external ear, and the eyelid or medial or lateral canthal area. Sixty-five percent of malignant melanomas occur in the facial region. Given that the face represents only 3.5% of total body surface area, the face is overrepresented when compared with other sites in the head and neck. Among the sites of origin in the head and neck, melanoma of the scalp and neck carries the highest mortality, with 10-year survival being only 60%. Melanomas of the ear, face, and eyelid have 10-year survival rates of 70%, 80%, and 90%, respectively.

Integrated plastic surgery residency applicant survey: characteristics of successful applicants and feedback about the interview process.

BACKGROUND: Integrated plastic surgery residency training is growing in popularity, bringing new challenges to program directors and applicants. The purpose of this study was to identify characteristics of successful applicants and to obtain feedback from applicants to improve the integrated plastic surgery residency training application and interview process. METHODS: An anonymous survey assessing applicant academic qualifications, number of interviews offered and attended, and opinions about the application and interview process was distributed electronically to the 2006 integrated plastic surgery residency training applicant class. The number of interviews offered was used as an indicator of potential applicant success. RESULTS: A 38 percent survey participation rate (139 of 367) was achieved. United States Medical Licensing Examination Step 1 score correlated with number of interview invitations (p < or = 0.001). Successful Alpha Omega Alpha designation (p < or = 0.001), high class rank (p = 0.034), presence of a plastic surgery residency program at the participant's school (p = 0.026), and authorship of one or more publications (p < or = 0.001) were associated with receiving greater number of interview invitations. Geographic location was an important consideration for applicants when applying to and ranking programs. Applicants desired interviews on weekdays and geographic coordination of interviews. CONCLUSIONS: Integrated plastic surgery residency training is highly competitive, with the number of interview invitations correlating with academic performance and, to a lesser extent, research. Applicant feedback from this survey can be used to improve the application and interview process.

Phenol-croton oil peel: establishing an animal model for scientific investigation.

BACKGROUND: Phenol-croton oil formulas for facial peeling contain a mixture of phenol, croton oil, hexachlorophene foam (Septisol; Steris Corp., Mentor, OH), and water. For years, it was felt that the active ingredient of the solution was phenol, with the view that croton oil was little more than an irritant. Hetter reported, based on clinical experience, that the addition of tiny amounts of croton oil to any concentration of phenol caused a deeper peel. He also noted that the number of applications of a phenol-croton oil solution also enhanced the peel effects. To date, there have been no animal studies that confirm these clinical observations. OBJECTIVE: The purpose of this study was to develop an animal model to further evaluate and refine the hypotheses of Hetter regarding the croton oil solution. METHODS: At the Medical College of Wisconsin, Milwaukee, WI, using a porcine animal model, 40 different solutions of phenol, water, croton oil, hexachlorophene foam, and ethyl alcohol, in 8 groupings, were applied to the flank according to grids. On days 1, 8, and 22, clinical observations were made and punch biopsies were obtained from all grids, including controls. All tissue samples were examined by a blinded dermatopathologist. RESULTS: The results were analyzed by both clinical and histologic observation. Solutions with any amount of croton oil added had a brisker inflammatory response than solutions without croton oil. The histologic examination of skin biopsies from the phenol-treated cells (with or without croton oil) demonstrated formation of sharply demarcated dermis with parallel collagen fiber bundles arranged horizontally when compared with the elastotic dermis of the control specimens. The depth of peel and time needed for healing were greater with 45 strokes than with 20 or 5 strokes. Replacing water with ethyl alcohol produced a less clinically significant peel. CONCLUSIONS: Phenol peels more deeply with increasing concentrations. Peel depth increases with increasing concentration of croton oil. Multiple applications of croton oil in phenol increases the depth of peel. The porcine model is a satisfactory model for studying chemoexfoliative agents.