[Peculiarities of regenerative processes after the plasty of osteochondral defects with combined cell-tissue grafts on the basis of autologous and allogeneic cell cultures from costal cartilage tissue].

From a position of in vivo regenerative medicine, the efficacy of plasty of osteochondral defects of the articular surface was evaluated in rabbits. The combined cell-tissue grafts were used with the demineralized spongy bone as a biomatrix and autologous or allogeneic cells from the rib cartilage tissue. Morphofunctional characteristics of the cell cultures obtained were studied using morphological, histochemical, immunohistochemical and flow cytometric methods. Cells had features typical to cartilage cell line. While the macroscopic appearance of the plasty area was similar, some differences of histogenesis were observed at the early stages after the placement of transplants containing autologous as well as allogeneic cells, into the osteochondral defect area. In both cases, the complete recovery of subchondral bone and hyaline cartilage took place.

[Oxygen therapy of gonarthrosis deformans]. / Kislorodoterapiia v lechenii deformiruiushchego gonartroza.

In the article is presented the comparative estimate of the oxygen therapy methods in treatment of the deforming gonarthrosis. The new method of treatment is described, including 4-5 courses of hyperbaric oxygenation therapy at 1-1.5 atms during 50 min and intraarticular introduction of oxygen. 3 groups of patients have been singled out. The proposed method have been applied with 32 patients. It turned out to be more effective and the course of treatment shorter as compared with the known methods: with application of hyperbaric oxygenation without local introduction of oxygen and localized introduction of oxygen in the joint without application of hyperbaric oxygenation.