Asunto(s)
Neoplasias de Cabeza y Cuello , Neoplasias de Tejido Fibroso , Anciano , Diagnóstico Diferencial , Femenino , Neoplasias de Cabeza y Cuello/diagnóstico , Neoplasias de Cabeza y Cuello/diagnóstico por imagen , Neoplasias de Cabeza y Cuello/cirugía , Humanos , Inmunohistoquímica , Imagen por Resonancia Magnética , Neoplasias de Tejido Fibroso/diagnóstico , Neoplasias de Tejido Fibroso/diagnóstico por imagen , Neoplasias de Tejido Fibroso/cirugía , Tomografía Computarizada por Rayos XAsunto(s)
Granuloma/diagnóstico , Sarcoidosis/diagnóstico , Enfermedades de la Lengua/diagnóstico , Corticoesteroides/uso terapéutico , Diagnóstico Diferencial , Femenino , Granuloma/tratamiento farmacológico , Granuloma/patología , Granuloma/cirugía , Humanos , Persona de Mediana Edad , Sarcoidosis/tratamiento farmacológico , Sarcoidosis/patología , Sarcoidosis/cirugía , Lengua/patología , Enfermedades de la Lengua/tratamiento farmacológico , Enfermedades de la Lengua/patología , Enfermedades de la Lengua/cirugíaAsunto(s)
Adenocarcinoma/secundario , Neoplasias Gingivales/secundario , Neoplasias Renales/diagnóstico , Adenocarcinoma/diagnóstico , Adenocarcinoma/diagnóstico por imagen , Adenocarcinoma/patología , Anciano , Diabetes Mellitus Tipo 1/complicaciones , Femenino , Neoplasias Gingivales/diagnóstico , Humanos , Hipertensión/complicaciones , Neoplasias Renales/diagnóstico por imagen , Neoplasias Renales/patología , UltrasonografíaRESUMEN
We report the sudden onset of bilateral hearing loss in a patient with Crohn's disease while the intestinal disease was quiescent. Antibodies directed against collagen type II were detected in the serum. Dramatic improvement of his hearing was observed under corticosteroid therapy. Diagnosis of autoimmune sensorineural hearing loss was established. This condition could be considered as an extraintestinal manifestation of Crohn's disease. Early diagnosis is mandated, as prompt and intensive treatment with corticosteroids and/or immunosuppressive drugs is effective and could prevent irreversible hearing loss.
Asunto(s)
Enfermedades Autoinmunes/etiología , Enfermedad de Crohn/complicaciones , Pérdida Auditiva Sensorineural/etiología , Enfermedad Aguda , Adulto , Audiometría , Enfermedades Autoinmunes/tratamiento farmacológico , Enfermedades Autoinmunes/fisiopatología , Enfermedad de Crohn/tratamiento farmacológico , Glucocorticoides/uso terapéutico , Pérdida Auditiva Sensorineural/tratamiento farmacológico , Pérdida Auditiva Sensorineural/fisiopatología , Humanos , Masculino , Prednisona/uso terapéuticoRESUMEN
We report a new case of primary atypical carcinoid of the larynx. This rare neuro-endocrine neoplasm of the larynx was initially mis diagnosed in 50% of the cases published. Since, characteristically these are lesions of the epilarynx causing dysphonia at early stages of development, the diagnosis should be kept in mind when the work-up for dysphonia reveals a small tumor of the epiglottis or aryepiglottic folds. The histological diagnosis should be oriented by Grimelius staining and confirmed immunoperoxidase marker studies for chromogranin and cytokeratin. Although, atypical carcinoids of the larynx are aggressive malignant tumors, the prognosis for early lesions of less than 1 cm is excellent. However, unlike early squamous cell carcinomas, these tumors do not respond well to radiation therapy. Primary surgery is the treatment of choice.
Asunto(s)
Cartílago Aritenoides , Tumor Carcinoide/diagnóstico , Neoplasias Laríngeas/diagnóstico , Adulto , Tumor Carcinoide/complicaciones , Tumor Carcinoide/terapia , Terapia Combinada , Estudios de Seguimiento , Humanos , Neoplasias Laríngeas/complicaciones , Neoplasias Laríngeas/cirugía , Masculino , Pronóstico , Trastornos de la Voz/etiologíaRESUMEN
A study of dysosmia and dysgeusia in the elderly was undertaken in 50 patients, according to a simplified protocol based on an interview, a complete ENT examination, chemical gustrometry and recognition olfactometry. As far as olfaction was concerned, 11% of the patients interviewed said they were hyposmic, whereas following the olfactometric examination, hyposmia was found in 25% of the patients. As far as gustation was concerned, 5% of the patients complained of parageusia. The chemical gustrometric examination revealed 4% of cases of hypogeusia. As a conclusion to this study, it appears that olfactory and gustatory disorders are well tolerated in the elderly, and are not a cause for referral. The recognition olfactometric examination permits the detection of hyposmia with a relatively remarkable frequency.