Effects of Photobiomodulation Therapy on Performance in Successive Time-to-Exhaustion Cycling Tests: A Randomized Double-Blinded Placebo-Controlled Trial.

The goal of this study was to investigate the effects of photobiomodulation therapy (PBMT) on performance, oxygen uptake (VO2) kinetics, and lower limb muscle oxygenation during three successive time-to-exhaustions (TTEs) in cyclists. This was a double-blind, randomized, crossover, placebo-controlled trial study. Sixteen cyclists (~23 years) with a cycling training volume of ~460 km/week volunteered for this study. In the first session, cyclists performed a maximal incremental test to determine maximal oxygen uptake and maximal power output (POMAX). In the following sessions, cyclists performed three consecutive TTEs at POMAX. Before each test, PBMT (135 J/thigh) or a placebo (PLA) was applied to both thighs. VO2 amplitude, O2 deficit, time delay, oxyhemoglobin (O2Hb), deoxyhemoglobin (HHb), and total hemoglobin (tHb) were measured during tests on the right vastus lateralis. The PBMT applied before three successive TTE increased performance of the first and second TTE (~10-12%) tests, speed of VO2 and HHb kinetics during the first test, and increased peripheral muscle oxygenation (increase in HHb and tHb) in the first and second exhaustion tests. However, the PBMT effects were attenuated in the third TTE, as performance and all the other outcomes were similar to the ones from the PLA intervention. In summary, PBMT application increased the first and second successive TTEs, speed of VO2, and muscle oxygenation.

Manipulation of Stroke Rate in Swimming: Effects on Oxygen Uptake Kinetics.

The study aimed to assess the effect of different front crawl stroke rates (SRs) in the oxygen uptake (̇VO2) kinetics and ̇VO2 peak, the total time to exhaustion (TTE), and blood lactate concentration ([La]) at 95% of the 400-m front crawl test (T400) mean speed (S400). Twelve endurance swimmers performed a T400 and four trials at 95% of the S400: (i) free SR, (ii) fixed SR (100% of the average free SR trial), (iii) reduced SR (90% of the average free SR trial), and (iv) increased SR (110% of the average free SR trial). ̇VO2 was accessed continuously with breath-by-breath analysis. The results highlighted: (i) the time constant at increased SR (13.3±4.2 s) was lower than in the reduced SR condition (19.5±2.6 s); (ii) the amplitude of the primary phase of ̇VO2 kinetics in the fixed SR (44.0±5.8 ml·kg-1·min-1) was higher than in the increased SR condition (39.5±6.4 ml·kg-1·min-1); and (iii) TTE was lower in the fixed SR (396.1±189.7 s) than the increased SR condition (743.0±340.0 s). The results indicate that controlled SR could be considered a swimming training strategy, focusing on physiological parameters overload.

Dose-response effect of photobiomodulation therapy on neuromuscular economy during submaximal running.

The purpose of this study was to verify the photobiomodulation therapy (PBMT) effects with different doses on neuromuscular economy during submaximal running tests. Eighteen male recreational runners participate in a randomized, double-blind, and placebo-controlled trial, which each participant was submitted to the same testing protocol in five conditions: control, placebo, and PBMT with doses of 15, 30, and 60 J per site (14 sites in each lower limb). The submaximal running was performed at 8 and 9 km h-1 during 5 min for each velocity. Muscle activation of the vastus lateralis (VL), vastus medialis (VM), rectus femoris (RF), biceps femoris (BF), and gastrocnemius lateralis (GL) was collected during the last minute of each running test. The root mean square (RMS) was normalized by maximal isometric voluntary contraction (MIVC) performed a priori in an isokinetic dynamometer. The RMS sum of all muscles (RMSLEG) was considered as main neuromuscular economy parameter. PBMT with doses of 15, 30, and 60 J per site [33 diodes = 5 lasers (850 nm), 12 LEDs (670 nm), 8 LEDs (880 nm), and 8 LEDs (950 nm)] or placebo applications occurred before running tests. For the statistical analysis, the effect size was calculated. Moreover, a qualitative inference was used to determine the magnitude of differences between groups. Peak torque and RMS during MIVCs showed small effect sizes. According to magnitude-based inference, PBMT with dose of 15 J per site showed possibly and likely beneficial effects on neuromuscular economy during running at 8 and 9 km h-1, respectively. On other hand, PBMT with doses of 30 and 60 J per site showed possible beneficial effects only during running at 9 km h-1. We concluded that PBMT improve neuromuscular economy and the best PBMT dose was 15 J per site (total dose of 420 J).