Asunto(s)
Carbapenémicos/farmacología , Infecciones por Klebsiella/microbiología , Klebsiella pneumoniae/enzimología , Complicaciones Infecciosas del Embarazo/microbiología , Resistencia betalactámica , beta-Lactamasas/biosíntesis , Antibacterianos/farmacología , Antibacterianos/uso terapéutico , Carbapenémicos/uso terapéutico , Femenino , Francia , Humanos , Recién Nacido , Infecciones por Klebsiella/diagnóstico , Klebsiella pneumoniae/aislamiento & purificación , Embarazo , Complicaciones Infecciosas del Embarazo/diagnóstico , TurquíaAsunto(s)
Costo de Enfermedad , Infertilidad/terapia , Programas Nacionales de Salud/economía , Técnicas Reproductivas , Francia/epidemiología , Humanos , Infertilidad/economía , Infertilidad/epidemiología , Infertilidad/psicología , Técnicas Reproductivas/efectos adversos , Técnicas Reproductivas/economía , Técnicas Reproductivas/psicología , Factores de RiesgoRESUMEN
BACKGROUND: This study was designed to determine the crude cumulative live-birth rates in a cohort initiating frozen donor semen treatment until completion. METHODS: This cohort study included 588 couples with primary infertility in one University Hospital centre. The treatment sequence involved first artificial insemination (AID) followed by IVF if necessary (IVF-D). Live birth, drop-out for personal or medical reasons and recourse to IVF-D were recorded for all patients. Live births and drop-out were expressed both as rates per cycle and crude cumulative rates. RESULTS: At the completion of AID and IVF-D cycles, 406 couples in the cohort (69%) achieved a live-birth and 182 couples (31%) discontinued treatment. In most cases, couples stopped treatment for personal reasons (74%) whereas fewer couples were denied further treatment for medical reasons (26%). CONCLUSIONS: This is the first report on the crude cumulative live-birth rate in a cohort after AID and IVF-D cycles. Although calculation based on crude cumulative live-birth rate shows lower results in comparison with life table analysis, this method allows patients to obtain an insight into their actual chances of achieving a successful pregnancy.