RESUMEN
We report the case of a 49-year-old white man with a chromophobe renal cell carcinoma associated with sarcomatoid differentiation, an uncommon yet an aggressive form of dedifferentiated renal cell carcinoma. In opposite to the conventional renal cell carcinoma, which may not always demonstrate avid FDG activity, the sarcomatoid differentiated chromophobe renal cell carcinoma shows intense FDG uptake on PET. This case highlights the role of FDG PET/CT in staging and restaging this type of rare renal cell carcinoma.
Asunto(s)
Carcinoma de Células Renales/diagnóstico por imagen , Neoplasias Renales/diagnóstico por imagen , Tomografía Computarizada por Tomografía de Emisión de Positrones , Carcinoma de Células Renales/patología , Fluorodesoxiglucosa F18 , Humanos , Neoplasias Renales/patología , Masculino , Persona de Mediana Edad , RadiofármacosAsunto(s)
Fibromatosis Agresiva/complicaciones , Fibromatosis Agresiva/diagnóstico , Lipomatosis/diagnóstico , Lipomatosis/etiología , Neoplasias del Sistema Nervioso Periférico/complicaciones , Neoplasias del Sistema Nervioso Periférico/diagnóstico , Neuropatía Ciática/etiología , Femenino , HumanosRESUMEN
Lipomatosis of nerve is a rare benign tumor-like process characterized by infiltration of the epineurium by adipose and fibrous tissue leading to nerve enlargement. We describe a case of lipomatosis of the sciatic nerve compressed by an adjacent desmoid tumor. This case supports the hypothesis that lipomatosis of nerve may form as a result of irritation or compression by adjacent structures.
Asunto(s)
Fibromatosis Agresiva/complicaciones , Fibromatosis Agresiva/diagnóstico , Lipomatosis/diagnóstico , Lipomatosis/etiología , Neoplasias del Sistema Nervioso Periférico/complicaciones , Neoplasias del Sistema Nervioso Periférico/diagnóstico , Neuropatía Ciática/etiología , Adulto , Antineoplásicos/uso terapéutico , Femenino , Fibromatosis Agresiva/tratamiento farmacológico , Humanos , Lipomatosis/tratamiento farmacológico , Neoplasias del Sistema Nervioso Periférico/tratamiento farmacológico , Neuropatía Ciática/diagnóstico , Neuropatía Ciática/prevención & control , Resultado del TratamientoRESUMEN
The recent observation of high flexibility in buckled boron nitride nanotubes (BNNTs) contradicts the pre-existing belief about BN nanotube brittleness due to the partially ionic character of bonding between the B and N atoms. However, the underlying mechanisms and relationships within the nanotube remained unexplored. This study reports for the first time the buckling mechanism in multi-walled BNNTs upon severe mechanical deformation. Individual BNNTs were deformed inside a transmission electron microscope (TEM) equipped with an in situ atomic force microscopy holder. High-resolution TEM images revealed that bent BNNTs form multiple rippling upon buckling. The critical strain to form the first ripple was measured as 4.1% and the buckling process was reversible up to 26% strain. As opposed to carbon nanotubes, the BNNTs buckled into V-shaped ripples rather than smooth wavy shapes. The rippling wavelength was quantified in terms of the outer diameter and thickness of the nanotubes. The BNNTs showed a larger rippling wavelength compared to that of CNTs with the same number of walls. This difference was explained by the tendency of BN structures to reduce the number of thermodynamically unfavorable B-B and N-N bonds at the sharp corners in the rippling regions. The BNNTs' structure also exhibited a higher fracture strain compared to their counterpart.
