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PLoS One ; 13(10): e0205305, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-30300407

RESUMEN

We aimed to compare the clinical outcomes between endovascular treatment and inframalleolar bypass surgery for critical limb ischemia (CLI) in patients with thromboangiitis obliterans (TAO) and to assess the role of bypass surgery in the era of innovative endovascular treatment. Between January 2007 and December 2017, a total of 33 consecutive patients with the diagnosis of TAO presenting with CLI who underwent endovascular treatment (endovascular group, n = 22) or bypass surgery to the pedal or plantar vessels (bypass group, n = 11) were included and analyzed retrospectively. The primary endpoint was defined as a major amputation of the index limb, and the secondary endpoint was defined as graft occlusion, regardless of the number of subsequent procedures. In the bypass group, six patients (55%) had undergone previous failed endovascular procedures and/or arterial bypass surgery to the index limb before inframalleolar bypass, and two patients (18%) received microvascular flap reconstruction after bypass surgery. During the median follow-up period of 32 months (range 1-115 months), there were no significant differences in primary and secondary endpoints between the two groups although the bypass group had a higher Rutherford class than the endovascular group. Kaplan-Meier survival analysis showed that there were similar limb salvage (P = 0.95) and graft patency rates (P = 0.39). In conclusion, endovascular treatment is a valid strategy leading to an acceptable limb salvage rate for TAO patients, and surgical bypass to distal target vessels could play a vital role in cases of previous failed endovascular treatment or extensive soft tissue loss of the foot.


Asunto(s)
Procedimientos Endovasculares/métodos , Isquemia/cirugía , Vena Safena/cirugía , Tromboangitis Obliterante/cirugía , Injerto Vascular/métodos , Adulto , Anciano , Amputación Quirúrgica/mortalidad , Amputación Quirúrgica/estadística & datos numéricos , Procedimientos Endovasculares/mortalidad , Femenino , Oclusión de Injerto Vascular/mortalidad , Oclusión de Injerto Vascular/patología , Humanos , Isquemia/mortalidad , Isquemia/patología , Recuperación del Miembro/mortalidad , Recuperación del Miembro/estadística & datos numéricos , Extremidad Inferior/irrigación sanguínea , Extremidad Inferior/patología , Extremidad Inferior/cirugía , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Vena Safena/patología , Análisis de Supervivencia , Tromboangitis Obliterante/mortalidad , Tromboangitis Obliterante/patología , Injerto Vascular/mortalidad
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