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1.
Appl Opt ; 59(20): 5957-5966, 2020 Jul 10.
Artículo en Inglés | MEDLINE | ID: mdl-32672739

RESUMEN

We applied the Hurst exponent technique to an experimental study of rough metallic surface profiles and the speckle patterns generated by them. Characterization of important statistical properties of the surface profile and speckle patterns were performed. We observed a clear correlation between the Hurst exponent of a surface profile and the one calculated from the associated speckle patterns. Therefore, in principle, information of the Hurst exponent of the profile can be obtained from the Hurst exponent of speckle patterns. Range and sampling analyses were performed in the Hurst exponent calculations showing the robustness of the method. As an additional application, we performed a basic simulation to show that the Hurst exponent is sensitive to surface waviness.

2.
Nature ; 546(7658): 406-410, 2017 06 15.
Artículo en Inglés | MEDLINE | ID: mdl-28538727

RESUMEN

Transmission of Zika virus (ZIKV) in the Americas was first confirmed in May 2015 in northeast Brazil. Brazil has had the highest number of reported ZIKV cases worldwide (more than 200,000 by 24 December 2016) and the most cases associated with microcephaly and other birth defects (2,366 confirmed by 31 December 2016). Since the initial detection of ZIKV in Brazil, more than 45 countries in the Americas have reported local ZIKV transmission, with 24 of these reporting severe ZIKV-associated disease. However, the origin and epidemic history of ZIKV in Brazil and the Americas remain poorly understood, despite the value of this information for interpreting observed trends in reported microcephaly. Here we address this issue by generating 54 complete or partial ZIKV genomes, mostly from Brazil, and reporting data generated by a mobile genomics laboratory that travelled across northeast Brazil in 2016. One sequence represents the earliest confirmed ZIKV infection in Brazil. Analyses of viral genomes with ecological and epidemiological data yield an estimate that ZIKV was present in northeast Brazil by February 2014 and is likely to have disseminated from there, nationally and internationally, before the first detection of ZIKV in the Americas. Estimated dates for the international spread of ZIKV from Brazil indicate the duration of pre-detection cryptic transmission in recipient regions. The role of northeast Brazil in the establishment of ZIKV in the Americas is further supported by geographic analysis of ZIKV transmission potential and by estimates of the basic reproduction number of the virus.


Asunto(s)
Infección por el Virus Zika/transmisión , Infección por el Virus Zika/virología , Virus Zika/aislamiento & purificación , Américas/epidemiología , Número Básico de Reproducción , Brasil/epidemiología , Variación Genética , Genoma Viral/genética , Humanos , Microcefalia/epidemiología , Microcefalia/virología , Epidemiología Molecular , Filogeografía , Análisis Espacio-Temporal , Virus Zika/genética , Infección por el Virus Zika/epidemiología
3.
Appl Opt ; 56(2): 330-335, 2017 Jan 10.
Artículo en Inglés | MEDLINE | ID: mdl-28085872

RESUMEN

In this work, we report on the analysis of speckle patterns produced by illuminating different rough surfaces with an optical vortex, a first-order (l=1) Laguerre-Gaussian beam. The generated speckle patterns were observed in the normal direction exploring four different planes: the diffraction plane, image plane, focal plane, and exact Fourier transform plane. The digital speckle patterns were analyzed using the Hurst exponent of digital images, an interesting tool used to study surface roughness. We show a proof of principle that the Hurst exponent of a digital speckle pattern is more sensitive with respect to the surface roughness when the speckle pattern is produced by an optical vortex and observed at a focal plane. We also show that Hurst exponents are not so sensitive with respect to the topological charge l. These results open news possibilities of investigation into speckle metrology once we have several techniques that use speckle patterns for different applications.

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