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Virchows Arch ; 449(3): 367-72, 2006 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-16855839

RESUMEN

Synovial sarcoma arising in the abdominal wall is a rare tumor. We report a case of a 38-year-old man who complained of abdominal pain. Physical examination revealed a firm mobile mass, 25 cm in diameter, in the left lower abdominal wall. The tumor was first thought to be a sarcoma arising from the omentum or mesentery. During surgery, a large tumor was found attached to the inner surface of the abdominal wall and compressing the gastrointestinal tract. On microscopic examination the tumor corresponded to a biphasic synovial sarcoma immunoreactive for cytokeratins (AE1/AE3, 7 and 19), epithelial membrane antigen and carcinoembryonic antigen in the epithelial tumor cells, for E-cadherin especially in their glandular structure, vimentin, CD99, and CD56 in the spindle cell component and for bcl-2 protein. The tumor recurred at the same site, and clinical course progressed to death 3 months after the initial diagnosis.


Asunto(s)
Neoplasias Abdominales/patología , Pared Abdominal/patología , Carcinosarcoma/patología , Sarcoma Sinovial/patología , Antígeno 12E7 , Neoplasias Abdominales/química , Neoplasias Abdominales/cirugía , Pared Abdominal/cirugía , Adulto , Antígenos CD/análisis , Biomarcadores de Tumor/análisis , Antígeno CD56/análisis , Cadherinas/análisis , Antígeno Carcinoembrionario/análisis , Carcinosarcoma/química , Carcinosarcoma/cirugía , Moléculas de Adhesión Celular/análisis , Resultado Fatal , Humanos , Queratinas/análisis , Masculino , Recurrencia Local de Neoplasia , Sarcoma Sinovial/química , Sarcoma Sinovial/cirugía , Tomografía Computarizada por Rayos X , Vimentina/análisis
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