[Experience of Endovascular Implantation of the WATCHMAN Device in Patients With Atrial Fibrillation].

Atrial fibrillation is one of most frequent heart rhythm disorders in clinical practice. In this article, we present data of review of relevant literature including consideration of prevention of thromboembolic complications. We also present our own experience of endovascular implantation of the WATCHMAN device in left atrial appendage of patients with atrial fibrillation.

[The use of computer pulse oximetry monitoring for screening of sleep apnea in patients of a hospital cardiology department].

In order to assess the overall prevalence of sleep apnea of obstructive and central origin in of patients hospital cardiology department we performed continuous pulse oximetry monitoring during sleep in all patients admitted over 2 months. Of the 139 patients reliable results were obtained in 125 (89.9%). In 72% of patients desaturation index was 5 or more, indicating probability of sleep apnea. In 36% of patients oxygen desaturation index was > or = 15, which corresponded to moderate forms of sleep apnea. And only 28% of patients had no pathological changes in the nocturnal oxygen saturation curve. Thus, in patients hospital cardiology department we revealed extremely high prevalence of sleep apnea of various origins. Showed the technical feasibility of the continuous pulse oximetry monitoring for mass screening of apnea during sleep.

[Effect of manual therapy on blood pressure in hypertensives with cervical osteochondrosis]. / Vliianie manual'noi terapii na arterial'noe davlenie u bol'nykh gipertonicheskoi bolezn'iu c sheinym osteokhondrozom.

The efficacy of drug (inderal, corinfar) treatment in combination with manual therapy (the course was 4-7 sessions) was examined in hypertensives with cervical osteochondrosis. The latter was evidenced by X-ray studies. Clinically, cervical osteochondrosis appeared as vertebrobasilar insufficiency. The vertebral artery bed displayed circulatory disorders documented by rheoencephalography, electroencephalography, ultrasound Doppler echography of the head and neck vessels. Treating the patients with drugs in combination with manual therapy resulted in improved circulation in the vertebral artery bed, lower clinical signs of vertebrobasilar insufficiency. There was a more persistent and more pronounced decrease in blood pressure with small-dose antihypertensive agents.

[The use of radioisotope study methods in cardiology practice]. / Primenenie radioizotopnykh metodov issledovaniia v kardiologicheskoi praktike.

Methods of radionuclide diagnosis modified with regard to the clinical problems and combined with new mathematic approaches to the processing of the data obtained make it possible to substantially enlarge the diagnostic information on myocardial contractility, central hemodynamics, the status and perfusion of the myocardium and to use it in combination with the latest research methods applied in cardiological patients.

[Effect of different immunomodulators on the subpopulations of immunocompetent cells. The immunomodulating therapy of respiratory diseases]. / Vliianie razlichnykh immunomoduliatorov na subpopuliatsii immunokompetentnykh kletok. Immunomoduliruiushchaia terapiia zabolevanii organov dykhaniia.

Subpopulation analysis of immunocompetent cells of peripheral blood was performed in 286 patients with bronchopulmonary diseases (acute and protracted pneumonia, chronic obstructive and non-obstructive bronchitis). All the examined manifested the presence of secondary immune deficiency of different nature. The authors describe the results of immunomodulatory therapy with levamisole, diuciphon, zixorin, catergen and prodigiosan. Discuss in detail possible causes of the development of immune deficiencies and the mechanisms of action of the immunomodulators.

[Analysis of immunocompetent cell subpopulations in chronic bronchitis patients during the use of different immunomodulating preparations]. / Analiz subpopuliatsii immunokompetentnykh kletok u bol'nykh khronicheskim bronkhitom na fone primeneniia razlichnykh immunomoduliruiushchikh preparatov.

Twenty-seven patients with chronic obstructive bronchitis and 47 patients with chronic non-obstructive bronchitis were subjected to subpopulation analysis of peripheral blood immunocompetent cells. Statistically significant changes in the content of T mu and T gamma cells, killer and suppressor activity of lymphocytes were discovered in patients with chronic bronchitis. One of the immunological differences between chronic obstructive and chronic non-obstructive bronchitis lies in the activity of Con A-induced suppressors, which is appreciably lowered in patients with chronic obstructive bronchitis.