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1.
Materials (Basel) ; 11(11)2018 Nov 11.
Artículo en Inglés | MEDLINE | ID: mdl-30423884

RESUMEN

In this study, the effect of austenite grain size on acicular ferrite (AF) nucleation in low-carbon steel containing 13 ppm Mg is determined. The average austenite grain size was calculated using OM Leica software. Results show that the predicted and experimental values of austenite grain size are extremely close, with a deviation of less than 20 µm. AF formation is difficult to induce by either excessively small and large austenite grain sizes; that is, an optimal austenite grain size is required to promote AF nucleation probability. The austenite grain size of 164 µm revealed the highest capacity to induce AF formation. The effects of the maximum distance of carbon diffusion and austenite grain size on the microstructure of Mg-containing low carbon steel are also discussed. Next, the pinning ability of different inclusion types in low-carbon steel containing 22 Mg is determined. The in situ observation shows that not every inclusion could inhibit austenite grain migration; the inclusion type influences pinning ability. The grain mobility of each inclusion was calculated using in situ micrographs of confocal scanning laser microscopy (CSLM) for micro-analysis. Results show that the austenite grain boundary can strongly be pinned by Mg-based inclusions. MnS inclusions are the least effective in pinning austenite grain boundary migration.

2.
Biofactors ; 44(1): 5-15, 2018 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-29322567

RESUMEN

Stilbenes are a large group of compounds with the C6 C2 C6 skeleton, in which two aromatic rings are connected by an ethylene bridge. Resveratrol and its structural analog, pterostilbene, are by far the two most widely researched stilbenes in terms of their beneficial bioactivities. However, the bioefficacy of these compounds is greatly reduced when consumed orally due to their poor aqueous solubility, which leads to poor bioavailability. To overcome the limitation, strategies improving their solubility, absorption, and systemic concentration were applied when designing a suitable edible delivery system. This review will summarize the findings from the studies evaluating the oral bioavailability of stilbenes with emphasize on the resveratrol and pterostilbene. It will also include the edible delivery systems currently available and their effect on the oral bioavailability. © 2018 BioFactors, 44(1):5-15, 2018.


Asunto(s)
Sistemas de Liberación de Medicamentos/métodos , Liposomas/química , Nanopartículas/química , Estilbenos/farmacocinética , Administración Oral , Animales , Disponibilidad Biológica , Emulsiones , Semivida , Humanos , Liposomas/administración & dosificación , Nanopartículas/administración & dosificación , Ratas , Resveratrol , Solubilidad , Estilbenos/sangre , Porcinos
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