Improved mammalian family phylogeny using gap-rare multiple sequence alignment: A timetree of extant placentals and marsupials.

The timing of mammalian diversification in relation to the Cretaceous-Paleogene (KPg) mass extinction continues to be a subject of substantial debate. Previous studies have either focused on limited taxonomic samples with available whole-genome data or relied on short sequence alignments coupled with extensive species samples. In the present study, we improved an existing dataset from the landmark study of Meredith et al. (2011) by filling in missing fragments and further generated another dataset containing 120 taxa and 98 exonic markers. Using these two datasets, we then constructed phylogenies for extant mammalian families, providing improved resolution of many conflicting relationships. Moreover, the timetrees generated, which were calibrated using appropriate molecular clock models and multiple fossil records, indicated that the interordinal diversification of placental mammals initiated before the Late Cretaceous period. Additionally, intraordinal diversification of both extant placental and marsupial lineages accelerated after the KPg boundary, supporting the hypothesis that the availability of numerous vacant ecological niches subsequent to the mass extinction event facilitated rapid diversification. Thus, our results support a scenario of placental radiation characterized by both basal cladogenesis and active interordinal divergences spanning from the Late Cretaceous into the Paleogene.

Intraspecific variation in metabolic rate and its correlation with local environment in the Chinese scorpion Mesobuthus martensii.

Scorpions are well known for their reduced resting metabolic rate (RMR) in comparison to typical arthropods. Since RMR is a key physiological trait linked with evolutionary fitness, it is expected that there may exist intraspecific RMR variation given the ecological and geographical heterogeneities across the distributional range of a species. Nevertheless, it is unclear whether RMR variation exists among scorpion populations. Here, we compared the RMR (VCO2) of 21 populations of the Chinese scorpion Mesobuthus martensii (Scorpiones: Buthidae) at 25°C after at least 3 months of laboratory acclimation. The following results were obtained. First, there was significant difference in RMR between sexes when body-weight effects were factored out. Second, significant local variation in RMR was detected by analyses of both variance and covariance, with one population showing significantly reduced RMR and another significantly increased RMR. Third, regression analysis indicated that the local mean temperature and mean annual days of rainfall were the two significant factors associated with the aforementioned inter-population difference in RMR. The implication of such an association was discussed.

Brief Introduction of Medical Insurance System in China.

China has one of the largest numbers of cancer patients. The huge expenses of medical care for cancer patients has brought heavy economic burden to the family. This paper briefly introduces the tumor medical insurance situation in China from the construction and composition of China's medical security system, the access of cancer patients to get health insurance, the challenges and developmental trend of China's medical security system, and two case studies that highlight different financial situations.